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Chemo Sucks. Science Is Changing That

Video vocabulary

driver

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US / ˈdraɪvə(r) /

UK / ˈdraɪvɚ /

A1
  • noun
  • People who move cattle from one place to another
  • Someone who operates a vehicle
  • A club with a wooden head used when playing golf

exact

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US / ɪɡ'zækt /

UK / ɪɡˈzækt /

A2
  • adjecitve
  • Completely correct; accurate; specific
  • verb
  • To get something, sometimes using force

why

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US / waɪ /

UK / hwaɪ, waɪ /

A1
  • adverb
  • Question word to ask for a reason
  • exclamation
  • (Used to express surprise or approval)

replace

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US / rɪ'pleɪs /

UK / rɪˈples /

A2
  • verb
  • To use instead of something else
  • To return an item to its original location

extremely

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US / ɪkˈstri:mli /

UK / ɪk'strimlɪ /

B1
  • adverb
  • In a way that is much more than usual or expected

through

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US / θru: /

UK / θru /

A2
  • adjecitve
  • having finished using or doing something
  • adverb
  • From the beginning of something until the end
  • preposition
  • Over, in, across an entire thing or place
  • Allowing you to pass between, or to
  • By a particular way or process; by the use of

monoclonal

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US / ˌmɒnəʊˈkləʊnəl /

UK / ˌmɑːnoʊˈkloʊnəl /

A1
  • adjecitve
  • Forming or derived from a single clone

time

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US / taɪm /

UK / taɪm /

A1
  • noun
  • Speed at which music is played; tempo
  • Point as shown on a clock, e.g. 3 p.m
  • Number of hours, minutes needed to do something
  • Occasion when something happens
  • Period or occasion that something occurred
  • Period in history or the past
  • Something measured in minutes, hours, days, etc.
  • How long an event takes; duration
  • verb
  • To check speed at which music is performed
  • To choose a specific moment to do something
  • To measure how long an event takes, e.g. a race
  • To schedule something to occur at a specific moment

anywhere

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US / ˈeniweə(r) /

UK / ˈeniwer /

A1
  • adverb
  • To any extent or degree (often used with not)
  • In, at or to any place
  • other
  • Use to indicate limits or variation

promise

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US / 'prɒmɪs /

UK / ˈprɑmɪs /

A1
  • verb
  • To say you will certainly do something

cellular

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US / 'seljələ(r) /

UK / ˈsɛljəlɚ /

B2
  • adjecitve
  • Concerning a cell of a living thing
  • (Of radio signals) functioning without wires

grow

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US / ɡrəʊ /

UK / ɡro /

A1
  • verb
  • To get bigger and more mature; make plants do this
  • To improve; to develop better skills over time
  • To develop and become bigger or taller over time

though

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US / ðəu /

UK / ðo /

A1
  • adverb
  • Although, despite the fact that

spare

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US / speə(r) /

UK / spɛr /

A2
  • adjecitve
  • Being extra or in reserve
  • noun
  • Extra part; something in reserve for replacements
  • verb
  • To make (money or time) available for
  • To save from being hurt or punished
  • To allow someone not to do something unpleasant

job

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US / dʒɒb /

UK / dʒɑ:b /

A1
  • noun
  • Something that must be done
  • Regular work at which you earn money

just

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US / dʒʌst /

UK / dʒʌst /

A1
  • adjecitve
  • Proper or appropriate; as is deserved
  • Doing or being what is right or fair
  • Legally correct; having enough evidence
  • adverb
  • Almost; nearly
  • Exactly at the time of
  • Exactly (the same as, like)

short

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US / ʃɔ:t /

UK / ʃɔrt /

A1
  • adverb
  • Less than what is needed
  • Suddenly stopping what you are saying or doing
  • verb
  • (Of electric circuit) to spark because faulty
  • adjecitve
  • Measuring a small distance
  • Happening for a small amount of time
  • Unfriendly or rude

alike

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US / əˈlaɪk /

UK / əˈlaɪk /

A2
  • adjecitve
  • Similar in appearance, manner or form
  • adverb
  • Equally; applied equally to several people/things

kill

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US / kɪl /

UK / kɪl /

A1
  • noun
  • Animal killed by a person or other animal
  • verb
  • To cause someone to experience a lot of pain
  • To end the life of a person or other living thing
  • To be very funny
  • To prevent something from continuing or operating
  • To do something unimportant to pass time quickly

system

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US / 'sɪstəm /

UK / ˈsɪstəm /

A1
  • adjecitve
  • Working in an organized, logical way
  • noun
  • Set of organized, planned ideas that work together

test

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US / test /

UK / test /

A1
  • noun
  • A medical examination
  • Action to establish the truth or nature of
  • Examination; questions to measure knowledge
  • verb
  • To be given a medical examination
  • To try to establish the truth or nature of
  • To ask a series of questions to measure knowledge

much

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US / mʌtʃ /

UK / mʌtʃ /

A1
  • adjecitve
  • Very; to a high level or degree
  • adverb
  • A lot; large amount; a high degree of
  • Nearly; basically
  • On many occasions; often
  • noun
  • A large amount; a great quantity

math

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US / mæθ /

UK / mæθ /

A2
  • noun
  • Study or science of numbers and shapes

equation

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US / ɪˈkweɪʒn /

UK / ɪˈkweʒən, -ʃən /

B1
  • noun
  • Mathematical statement showing things to be equal
  • Complex set of different facts, ideas or issues

mutate

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US / mju:'teɪt /

UK / ˈmjutet,mjuˈtet /

B2
  • verb
  • To develop into another thing; change

traditional

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US / trəˈdɪʃənl /

UK / trəˈdɪʃənəl /

A2
  • adjecitve
  • Involved in a custom or event common to a people

specifically

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US / spəˈsɪfɪkli /

UK / spəˈsɪfɪkli /

A2
  • adverb
  • As regards a particular thing; closely related to
  • In particular

approachable

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US / əˈprəʊtʃəbl /

UK / əˈproʊtʃəbl /

B1
  • adjecitve
  • Easy to talk to or deal with

circumstance

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US / 'sɜ:kəmstəns /

UK / ˈsɚkəmˌstæns /

A2
  • noun
  • Condition or fact that affects a situation

molecule

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US / ˈmɒlɪkju:l /

UK / ˈmɑlɪˌkjul /

B2
  • noun
  • Two or more atoms chemically combined

send

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US / send /

UK / sɛnd /

A1
  • verb
  • To cause to behave or respond in a particular way
  • To cause mail or packages to go to another place
  • To move something quickly in a particular way
  • To give information or greetings to someone

since

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US / sɪns /

UK / sɪns /

A1
  • adverb
  • At a point before the present time
  • conjunction
  • For this reason; because
  • preposition
  • From the time in the past that

graph

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US / græf /

UK / ɡræf /

A2
  • noun
  • Image expressing numerical data in lines or shapes
  • verb
  • To show data using images

cycle

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US / ˈsaɪkl /

UK / ˈsaɪkəl /

A2
  • noun
  • Series of regular and repeated actions
  • Bicycle, bike
  • verb
  • To go through a series of events repeatedly
  • To ride on a bicycle

convince

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US / kən'vɪns /

UK / kənˈvɪns /

A2
  • verb
  • To persuade someone, or make them feel sure

amazing

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US / ə'meɪzɪŋ /

UK / ə'meɪzɪŋ /

A2
  • adjecitve
  • Surprising in a pleasing way
  • verb
  • To cause wonder; to surprise completely

begin

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US / bɪ'ɡɪn /

UK / ˈbeɡɪn /

A1
  • verb
  • To do the first part of an action; to start

therapy

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US / 'θerəpɪ /

UK / ˈθɛrəpi /

B2
  • noun
  • Treatment to help cure an illness

personal

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US / ˈpɜ:sənl /

UK / ˈpɚsənəl /

A2
  • adjecitve
  • Done by or to a particular person; individual
  • Concerning a person's private life or feelings

computer

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US / kəmˈpju:tə(r) /

UK / kəmˈpjutɚ /

A1
  • noun
  • Machine for storing data, accessing the internet

those

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US / ðəʊz /

UK / ðoz /

A1
  • determiner
  • The people or things we are talking about
  • pronoun
  • The objects far from the speaker

depend

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US / dɪˈpend /

UK / dɪˈpend /

B1
  • verb
  • Be controlled or determined by (someone/something)

amount

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US / ə'maʊnt /

UK / əˈmaʊnt /

A1
  • noun
  • Quantity of something
  • verb
  • To add up to a certain figure

chromosome

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US / ˈkrəʊməsəʊm /

UK / ˈkroʊməsoʊm /

C2
  • noun
  • Cell structures that carry the genetic material

smart

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US / smɑ:t /

UK / smɑ:rt /

A2
  • adjecitve
  • Fashionable; well-dressed; well-groomed
  • Looking clean, neat and stylish
  • (Of phones, weapons) with clever features
  • Associated with rich, popular and stylish people
  • Clever; with intelligence
  • adverb
  • Energetic or quick in motion or movement
  • In a clever way; with intelligence
  • noun
  • Feeling of being hurt and upset
  • Sharp, burning pain
  • verb
  • To feel hurt or upset
  • To hurt with an unexpected sharp or burning pain

definitely

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US / ˈdefɪnətli /

UK / ˈdefɪnətli /

A2
  • adverb
  • Without question; beyond doubt

success

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US / sək'ses /

UK / səkˈsɛs /

A2
  • noun
  • Achievement of a desired purpose or goal
  • A successful person; one who achieved their aims

stuff

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US / stʌf /

UK / stʌf /

A1
  • noun
  • Generic description for things, materials, objects
  • verb
  • To push material inside something, with force

replicate

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US / 'replɪkeɪt /

UK / ˈrɛplɪˌket /

A1
  • verb
  • To make one or more exact copies of itself
  • To repeat something (e.g. experiment, process)

fact

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US / fækt /

UK / fækt /

A1
  • noun
  • Something that is known or proved to be true

for

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US / fə(r) /

UK / fɔr,fə /

A1
  • preposition
  • Used to show the purpose, or need of something

individualize

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US / ˌɪndɪˈvɪdʒuəlaɪz /

UK / ˌɪndəˈvɪdʒuəˌlaɪz /

A1
  • verb
  • To make something personal to you; personalize

combination

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US / ˌkɒmbɪ'neɪʃn /

UK / ˌkɑmbəˈneʃən /

B1
  • noun
  • Series of letters or numbers needed to open a lock
  • Act or result of mixing things together

fond

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US / fɒnd /

UK / fɑ:nd /

B1
  • adjecitve
  • Happy and loving; To like someone or something very much

well

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US / wel /

UK / wɛl /

A1
  • adjecitve
  • Being in a fortunate, good condition or state
  • Healthy and in good condition
  • adverb
  • In an acceptable, proper, or successful manner
  • In a complete, total, or full manner
  • A great and considerable degree
  • In a successful way, in a good or satisfactory way
  • exclamation
  • Used to begin or continue a particular statement
  • Used to show you want to start saying something
  • Used to express that you are waiting for a reply
  • You say this to change the topic of a conversation
  • Used to indicate you are making a final remark
  • noun
  • Long deep hole in the ground to get water
  • verb
  • To cause your eyes to fill with tears

gauntlet

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US / ˈgɔ:ntlət /

UK / ˈɡɔntlɪt, ˈɡɑnt- /

C1
  • noun
  • Thick heavy glove worn to protect hands and arms

clear

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US / klɪə(r) /

UK / klɪr /

A1
  • adjecitve
  • Empty; without anything in it or on it
  • Being certain and without doubt
  • Being without any streaks, spots, or cracks
  • Easy to understand; well-explained; obvious
  • adverb
  • Completely; entirely; through the whole of
  • Away from; free from
  • verb
  • To recover from or remove a problem
  • To get rid of the entire contents of
  • To give permission for something to happen
  • To make a place or surface empty by removing
  • To prove that someone is not guilty or to blame

mathematical

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US / ˌmæθə'mætɪkl /

UK / ˌmæθəˈmætɪkəl /

A2
  • adjecitve
  • Concerning numbers and equations

england

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US / 'ɪŋɡlənd /

UK / ˈɪŋɡlənd /

A1
  • proper noun
  • A European country that forms the largest and most southern part of Great Britain and of the United

lymphoma

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US / lɪmˈfəʊmə /

UK / lɪmˈfoʊmə /

C1
  • noun
  • Type of cancer that affects the lymph nodes

part

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US / pɑ:t /

UK / pɑ:rt /

A1
  • adjecitve
  • To some degree; half; not fully
  • noun
  • Division of a book
  • Ratio of something, e.g. 3 of gin, 1 of tonic
  • A line in a person's hair, made with a comb
  • Character an actor plays on stage, movie, or TV
  • Some, but not all of a specific thing
  • Role in causing something to happen
  • verb
  • To make a line in a person's hair, by using a comb
  • To move two things apart creating a space
  • To leave someone, or to break off a relationship

with

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US / wɪð /

UK / wɪð, wɪθ /

A1
  • preposition
  • As an employee of a certain company
  • Against something or someone
  • By using something as a means
  • Due to; because of
  • Including
  • Possessing as a feature
  • Related to
  • (Of the manner/attitude by which you do something)
  • Used to express that people or things are together

manage

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US / ˈmænɪdʒ /

UK / ˈmænɪdʒ /

A1
  • verb
  • To survive hardships and difficulties; to cope
  • To run or operate a business by directing others

challenge

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US / 'tʃælɪndʒ /

UK / ˈtʃæləndʒ /

A2
  • noun
  • An activity you wish to try that may be hard to do
  • Act of formally inviting someone to compete
  • A question to determine correctness of something
  • verb
  • To formally invite someone to compete at something
  • To question the correctness of something

hodgkin

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US / ˈhɒdʒkɪn /

UK / ˈhɑːdʒkɪn /

A1

review

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US / rɪˈvju: /

UK / rɪˈvju /

A2
  • noun
  • Examination of soldiers and supplies
  • Opinion, as in a paper, about movie, book, or play
  • Studying again to remind yourself about something
  • verb
  • To carefully look at the quality of something
  • To formally examine something in the military
  • To write an opinion about movie, book, or play
  • To study again to remind yourself about something

estimate

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US / 'estɪmət /

UK / ˈɛstəˌmet /

A2
  • noun
  • Guess or calculation of cost, size or value
  • verb
  • To guess or calculate the cost, size or value of

interactive

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US / ˌɪntərˈæktɪv /

UK / ˌɪntɚˈæktɪv /

A2
  • adjecitve
  • Acting or influencing others

mechanism

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US / 'mekənɪzəm /

UK / ˈmɛkəˌnɪzəm /

B1
  • noun
  • Part of a machine that performs a certain function
  • System or process for achieving a certain result

slightly

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US / ˈslaɪtli /

UK / ˈslaɪtli /

B1
  • adverb
  • Only a little

have

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US / həv /

UK / hæv /

A1
  • verb
  • To drink, smoke, eat or use something
  • To experience the effects of something
  • To organize an event, or join in an activity
  • To own, possess, or hold something
  • To cause to happen or produce a particular effect

hundred

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US / 'hʌndrəd /

UK / ˈhʌndrɪd /

A1
  • number
  • 100

notice

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US / 'nəʊtɪs /

UK / ˈnotɪs /

A1
  • noun
  • Time by when you must leave, e.g. if you are fired
  • Paper with an announcement, e.g. pinned to a board
  • verb
  • To become aware by sight, touch, or hearing

model

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US / ˈmɒdl /

UK / ˈmɑ:dl /

A2
  • adjecitve
  • Being an excellent example of
  • noun
  • Person who wears fashion to show it to the public
  • A small scale copy of a full original
  • verb
  • To wear and display clothes at a fashion show
  • To make a small scale copy of a full original

before

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US / bɪˈfɔ:(r) /

UK / bɪˈfɔr,-ˈfor /

A1
  • adverb
  • At a time earlier than the present; previously
  • conjunction
  • In advance of something happening
  • preposition
  • In front of someone or something

problem

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US / ˈprɒbləm /

UK / ˈprɑbləm /

A1
  • adjecitve
  • Causing trouble
  • noun
  • Something difficult to deal with or causes trouble
  • Question to show understanding of a math concept

chemotherapy

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US / ˌki:məʊˈθerəpi /

UK / ˌki:moʊˈθerəpi /

B2
  • noun
  • Treatment of diseases using chemicals

without

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US / wɪˈðaʊt /

UK / wɪðˈaʊt, wɪθ- /

A1
  • preposition
  • Not with; not having

know

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US / nəʊ /

UK / noʊ /

A1
  • verb
  • To be familiar with a person or place, thing
  • To feel sure or be convinced about something
  • To discover or be aware of something
  • To be able to distinguish
  • To have knowledge of things

plan

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US / plæn /

UK / plæn /

A1
  • noun
  • Drawing of how something should be done or made

penicillin

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US / ˌpenɪ'sɪlɪn /

UK / ˌpɛnɪˈsɪlɪn /

C1
  • noun
  • Medicine that treats infection by killing bacteria

immunotherapy

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US / ˌɪmjunoʊˈθɛrəpi /

UK / /

A1
  • noun
  • Therapy designed to produce immunity to a disease or to enhance resistance by the immune system

almost

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US / 'ɔ:lməʊst /

UK / ˈɔlˌmost, ɔlˈmost /

A1
  • adverb
  • Only a little less than, nearly, not quite

hand

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US / hænd /

UK / hænd /

A1
  • noun
  • Cards given to a player in a card game
  • Piece of a clock that points to the time
  • Someone who performs physical tasks or work
  • Body part at the end of a person's arm
  • Help for someone performing a particular action
  • Condition of having power or influence
  • Member of the crew of a ship
  • verb
  • To give something to someone personally

mind

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US / maɪnd /

UK / maɪnd /

A1
  • noun
  • One's opinion or way of thinking about something
  • Part of humans that allows us to think or feel
  • verb
  • To be bothered or upset by something
  • To take care of someone e.g. as a bodyguard

alive

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US / ə'laɪv /

UK / əˈlaɪv /

A2
  • adjecitve
  • Living; not dead

premium

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US / ˈpri:miəm /

UK / ˈprimiəm /

B1
  • adjecitve
  • Having a higher than normal quality
  • noun
  • Money paid as a fee for insurance

next

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US / nekst /

UK / nɛkst /

A1
  • adverb
  • The one that follows another in time or order
  • At a time or place directly after the present one
  • noun
  • The one that follows after
  • adjecitve
  • Immediately after the previous one
  • First occurrence after the present one

quickly

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US / ˈkwɪkli /

UK / ˈkwɪklɪ /

A1
  • adverb
  • Without taking a lot of time; fast

steady

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US / 'stedɪ /

UK / ˈstɛdi /

B2
  • adjecitve
  • Happening or developing at a regular rate
  • Continuing without stopping or changing over time
  • Firmly fixed or supported; not likely to fall over
  • noun
  • Your boyfriend or girlfriend
  • verb
  • To make constant, unchanging or staying the same
  • To hold something/someone so they stop moving

testicular

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US / tes'tɪkjələ(r) /

UK / tɛˈstɪkjəlɚ /

C1
  • adjecitve
  • Concerning or involving the testicles

often

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US / ˈɔfən /

UK / ˈɔfən,ˈɑfən,ˈɔftən,ˈɑf- /

A1
  • adverb
  • Many times; frequently; on many occasions

cure

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US / kjʊə(r) /

UK / kjʊr /

B1
  • noun
  • Something that solves a problem or makes it better
  • Medical treatment making a sick person healthy
  • verb
  • To fix or improve a problem
  • To make someone healthy or make a disease go away
  • To keep food from going bad by drying or salting

away

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US / ə'weɪ /

UK / əˈwe /

A1
  • adjecitve
  • Not present
  • adverb
  • Disappear completely
  • Doing something with a lot of energy
  • Not here; far from here; in a different direction
  • To a different area, location

tangle

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US / ˈtæŋgl /

UK / ˈtæŋɡəl /

B2
  • verb
  • To involve in troubles that are hard to escape
  • (Of string, etc.) to be knotted up and hard to undo

guarantee

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US / ˌɡærən'ti: /

UK / ˌɡærənˈti /

A2
  • noun
  • A promise to repair a broken product
  • Promise that something will be done as expected
  • verb
  • To promise to repair a broken product
  • To promise that something will happen or be done
  • To promise to pay if another person fails to do so

biology

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US / baɪˈɒlədʒi /

UK / baɪˈɑlədʒi /

A2
  • noun
  • The study of living things

design

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US / dɪˈzaɪn /

UK / dɪˈzaɪn /

A1
  • noun
  • The way something is planned, to fulfill a purpose
  • verb
  • To plan in a particular way to fulfill a purpose
  • To think of a plan

all

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US / ɔ:l /

UK / ɔl /

A1
  • adverb
  • Completely; totally
  • determiner
  • Being every one of something
  • pronoun
  • 100% of something; the complete amount

viewer

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US / ˈvju:ə(r) /

UK / ˈvjuɚ /

A2
  • noun
  • Special machine to look at pictures
  • Someone who watches, e.g. television

damage

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US / ˈdæmɪdʒ /

UK / ˈdæmɪdʒ /

A2
  • noun
  • Physical harm that is done to something
  • verb
  • To harm physically; to hurt or break something

their

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US / ðɛː /

UK / ðer /

A1
  • determiner
  • Belonging to them

batch

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US / bætʃ /

UK / bætʃ /

B2
  • noun
  • Amount of something that is produced at one time
  • A group of things made or done together
  • verb
  • To combine or arrange together into a group

move

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US / mu:v /

UK / muv /

A1
  • noun
  • Act of moving a playing piece in chess, etc.
  • An action; doing something
  • Step taken to achieve a goal
  • verb
  • To cause someone to have certain emotions
  • To cause something to change to a different place
  • To change where people live or a business operates
  • To take action to do or achieve something

harmful

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US / ˈhɑ:mfl /

UK / ˈhɑ:rmfl /

A2
  • adjecitve
  • Likely to cause damage or injury

scishow

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US / /

UK / /

A1

work

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US / wɜ:k /

UK / wɚk /

A1
  • adjecitve
  • Activity completed in order to make money
  • noun
  • The product of some artistic or literary endeavor
  • Everything created by an author, artist, musician
  • Activity you do in order to make money
  • Place of employment
  • Final product or result of a some labor or effort
  • verb
  • To bring into a specific state of success
  • To be functioning properly, e.g. a car
  • To do your job in your company or workplace
  • To make an effort to do something
  • To operate a machine or device

old

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US / əʊld /

UK / old /

A1
  • adjecitve
  • Having existed for a long time, not young or new
  • Age of a person since birth

link

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US / lɪŋk /

UK / lɪŋk /

A2
  • noun
  • Any one of the rings that are part of a chain
  • Connection between two or more things or people
  • Webpage item you click to go to another webpage
  • verb
  • To join or connect together

between

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US / bɪˈtwi:n /

UK / bɪˈtwin /

A1
  • preposition
  • From one person, thing, or place, to another
  • In the space that separates two objects
  • Among two or more people who share something

personally

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US / ˈpɜ:sənəli /

UK / ˈpəsənəli /

A2
  • adverb
  • By a specific person, and not by anyone else
  • Knowing someone as a friend, or closely

pretty

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US / 'prɪtɪ /

UK / ˈprɪti /

A1
  • adjecitve
  • Being attractive to the eye in a simple way
  • adverb
  • Very; to a great degree

transcribe

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US / træn'skraɪb /

UK / trænˈskraɪb /

B2
  • verb
  • To make a written copy of something spoken

general

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US / 'dʒenrəl /

UK / ˈdʒɛnərəl /

A1
  • adjecitve
  • Widespread, normal or usual
  • noun
  • Top ranked officer in the army

account

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US / ə'kaʊnt /

UK / əˈkaʊnt /

A1
  • noun
  • An advantage
  • Arrangement with a bank to keep your money for you
  • An invoice for things bought
  • Arrangement whereby you can use online services
  • A description, often written, of events; report

intimately

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US / 'ɪntɪmɪtlɪ /

UK / ˈɪntəmɪtlɪ /

B2
  • adverb
  • Privately and personally

symptom

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US / 'sɪmptəm /

UK / ˈsɪmtəm, ˈsɪmp- /

B1
  • noun
  • Sign that suggests that there is a problem

bit

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US / bɪt /

UK / bɪt /

A1
  • noun
  • Device put in a horse's mouth to control it
  • Small piece of something
  • verb
  • (E.g. of fish) to take bait and be caught

diagnose

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US / ˈdaɪəgnəʊz /

UK / ˌdaɪəgˈnoʊs /

B1
  • verb
  • To determine the cause of an illness or problem

its

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US / ɪts /

UK / ɪts /

A1
  • adjecitve
  • Referring to or belonging to ‘it’
  • determiner
  • Of something; belonging or related to something
  • other
  • Possessive form of “it”

acute

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US / əˈkju:t /

UK / əˈkjut /

B1
  • adjecitve
  • (Of an angle in math) of less than 90 degrees
  • Strong; very serious or severe

thank

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US / θæŋk /

UK / θæŋk /

A1
  • verb
  • To tell someone you are grateful to them

look

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US / lʊk /

UK / lʊk /

A1
  • noun
  • Person's beauty or physical attractiveness
  • Particular style of dress, clothes, or appearance
  • The way someone, something appears to be
  • Act of searching for or examining something
  • verb
  • To appear to be; seem

receptor

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US / rɪˈseptə(r) /

UK / rɪˈseptər /

B2
  • noun
  • A nerve ending that changes stimuli into impulses

possible

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US / ˈpɒsəbl /

UK / ˈpɑsəbəl /

A1
  • adjecitve
  • Being able or appropriate for a task or purpose
  • Having a chance of happening, or being true

risk

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US / rɪsk /

UK / rɪsk /

A1
  • noun
  • Actions that cause potential problems
  • verb
  • To do something potentially dangerous or foolish

suffix

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US / ˈsʌfɪks /

UK / ˈsʌfɪks /

B2
  • noun
  • Part of a word after the root, e.g. -ment, -ly

background

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US / ˈbækgraʊnd /

UK / ˈbækˌɡraʊnd /

A2
  • noun
  • Images, color, or information behind the main one
  • Someone's personal work and educational history
  • A position not as important as the main event
  • Past events that influence things in the present

avenue

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US / 'ævənju: /

UK / ˈævəˌnu, -ˌnju /

B1
  • noun
  • Wide street
  • Way to approach something or some issue
  • other

regular

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US / ˈregjələ(r) /

UK / ˈrɛɡjəlɚ /

A2
  • adjecitve
  • Having an equal amount of space or time in between
  • Occurring or being done frequently
  • Being normal, usual, or average
  • noun
  • Customers who frequently visit a place
  • Soldier who has a permanent job in the army

medicine

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US / ˈmedsn /

UK / ˈmɛdɪsɪn /

A2
  • noun
  • Something used in treating illness or pain
  • Science of preventing, treating, or curing disease

very

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US / 'verɪ /

UK / ˈvɛri /

A1
  • adjecitve
  • Concerning a large degree or amount
  • adverb
  • A lot; much; many
  • Used to stress or emphasize a noun

virus

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US / 'vaɪrəs /

UK / ˈvaɪrəs /

B1
  • noun
  • File secretly put on computers to cause harm
  • Living organism that causes disease or sickness

way

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US / weɪ /

UK / we /

A1
  • adverb
  • Used to emphasize the amount of something
  • noun
  • Particular aspect of something being thought about
  • One of various choices that could be made
  • Particular existing condition or state
  • (Often long) distance or length of time
  • How something is done
  • Route to go to a place
  • Small street
  • Usual behavior, emotions or habits of someone

they

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US / ðeɪ /

UK / ðe /

A1
  • pronoun
  • Two or more people, animals, or things

everything

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US / 'evrɪθɪŋ /

UK / ˈɛvriˌθɪŋ /

A1
  • pronoun
  • All of the things mentioned

personalize

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US / ˈpɜ:sənəlaɪz /

UK / ˈpɜ:rsənəlaɪz /

C1
  • verb
  • To make personal or more personal

option

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US / 'ɒpʃn /

UK / ˈɑpʃən /

A2
  • noun
  • A choice
  • Right to buy or sell at a certain price and time

building

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US / ˈbɪldɪŋ /

UK / ˈbɪldɪŋ /

A1
  • noun
  • A structure with a roof and walls, e.g. a house
  • verb
  • To establish e.g. a reputation, over time
  • To construct a house, office, factory

space

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US / speɪs /

UK / spes /

A1
  • noun
  • Empty area kept for a specific reason, like a car
  • Empty area with nothing in it
  • Area in the sky where the stars are
  • Area between written words on a page
  • verb
  • To make a certain distance or time between

common

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US / 'kɒmən /

UK / ˈkɑmən /

A1
  • adjecitve
  • Shared; Belonging to or used by everyone
  • Typical, normal; not unusual
  • noun
  • Area in a city or town that is open to everyone
  • Field near a village owned by the local community

show

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US / ʃəʊ /

UK / ʃo /

A1
  • noun
  • False display of love, emotion or action
  • An event for displaying or promoting goods
  • Play, opera or theater production
  • Presentation that is broadcast on TV or radio
  • verb
  • To be easily seen or displayed
  • To display your emotions or feelings
  • To let someone see something; display
  • To explain or teach how something is done
  • To lead someone somewhere; point them to something
  • To prove something to be true, correct
  • To reveal or allow something to be seen

year

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US / jə: /

UK / jɪr /

A1
  • noun
  • Unit of time equal to 12 months or 365 or 366 days
  • Used to refer to the age of a person

interfere

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US / ˌɪntə'fɪə(r) /

UK / ˌɪntɚˈfɪr /

B1
  • verb
  • To get involved in something not your business

newly

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US / ˈnu:li:, ˈnju:- /

UK / ˈnuli, ˈnju- /

A2
  • adverb
  • Very recently; just done or made

ones

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US / wʌnz /

UK / wʌnz /

A1
  • number
  • Number 1, a single person or thing

free

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US / fri: /

UK / fri /

A1
  • adjecitve
  • Living, happening without being controlled
  • Costing no money
  • Not working; not busy
  • verb
  • To release (e.g. bird) from a cage or prison

this

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US / ðɪs /

UK / ðɪs /

A1
  • adjecitve
  • Used to indicate something already been discussed
  • Used to indicate something happening around now
  • adverb
  • An indication by a physical motion or gesture
  • A specific amount of
  • determiner
  • Person, thing, or idea near you
  • pronoun
  • Person, thing that has already been discussed

five

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US / faɪv /

UK / faɪv /

A1
  • number
  • 5

simply

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US / ˈsɪmpli /

UK / ˈsɪmpli /

A1
  • adverb
  • In an easy or clear manner

cheap

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US / tʃi:p /

UK / tʃip /

A1
  • adjecitve
  • Not costing a lot of money
  • Having a low quality or value
  • Not liking to spend money; mean; stingy

inhibitor

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US / ɪnˈhɪbɪtə(r) /

UK / ɪnˈhɪbɪtɚ /

B1
  • noun
  • Substance that retards or stops an activity

cancerous

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US / 'kænsərəs /

UK / ˈkænsɚrəs /

B1
  • adjecitve
  • Being a growth caused by abnormal cell division

mutation

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US / mju:'teɪʃn /

UK / mjuˈteʃən /

B2
  • noun
  • Change that changes genetic structure

you

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US / jʊ /

UK / ju /

A1
  • pronoun
  • Person someone is speaking or writing to
  • Person or people in general

little

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US / 'lɪtl /

UK / ˈlɪtl /

A1
  • adjecitve
  • Being short in length of time
  • Not great in size, amount, or degree; small
  • Being very young or younger than others
  • adverb
  • By an amount or degree that is not very much
  • Not often; rarely
  • noun
  • A person's name

arm

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US / ɑ:m /

UK / ɑrm /

A1
  • noun
  • Part of your body from your shoulder to your hand
  • A branch of another object e.g. company
  • The side part of a chair where your arms go
  • The influence or power an authority has
  • verb
  • To activate a weapon or bomb for use
  • To give a gun or other weapon to a person or group

message

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US / 'mesɪdʒ /

UK / ˈmɛsɪdʒ /

A2
  • noun
  • Main idea or theme in a story, book, or film
  • Piece of information that is told/given to someone
  • verb
  • To communicate using text

specific

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US / spəˈsɪfɪk /

UK / spɪˈsɪfɪk /

A2
  • adjecitve
  • Precise; particular; just about that thing
  • Concerning one particular thing or kind of thing

division

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US / dɪ'vɪʒn /

UK / dɪˈvɪʒən /

B1
  • noun
  • How many times a number is contained in another
  • One part of an organization
  • Act of dividing or separating into parts
  • Something that acts as a separating line or point

molecular

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US / mə'lekjələ(r) /

UK / məˈlɛkjəlɚ /

B2
  • adjecitve
  • About or caused by molecules

how

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US / haʊ /

UK / haʊ /

A1
  • adjecitve
  • To what degree? in what amount?
  • adverb
  • (Used to explain the way to do something)
  • exclamation
  • For what purpose or reason?
  • (Used to ask someone or something's condition)

the

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US / ðə /

UK / ðə /

A1
  • article
  • Used to refer to something already mentioned
  • Used to show there is only one of something
  • determiner
  • Used to describe all of a family

below

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US / bɪ'ləʊ /

UK / bɪˈlo /

A1
  • preposition
  • In a lower position, place, or level

treat

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US / tri:t /

UK / trit /

A1
  • noun
  • Something you buy for others as a surprise present
  • something that tastes good and that is not eaten often
  • verb
  • To pay for the food or enjoyment of someone else
  • To use medical methods to try to cure an illness
  • To act in a certain way toward someone

flip

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US / flɪp /

UK / flɪp /

B2
  • noun
  • Act of turning your body in the air; somersault
  • Movement of something from one position to another
  • verb
  • To turn your body in the air, as in gymnastics
  • To move into a different position quickly
  • To move a button or switch to turn on or off

goal

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US / ɡəʊl /

UK / ɡol /

A2
  • noun
  • Something you try to do or achieve; an aim
  • (Sports) net into which you put a ball to score
  • (Sports) act of scoring by putting a ball in a net

effective

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US / ɪˈfektɪv /

UK / ɪˈfɛktɪv /

A1
  • adjecitve
  • Working efficiently to produce a desired result

breast

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US / brest /

UK / brɛst /

B1
  • noun
  • Fleshy part of a woman's body for feeding babies
  • (Poetic) upper front part of the body; the heart

three

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US / θri: /

UK / θri /

A1
  • number
  • Number 3

unfortunately

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US / ʌnˈfɔ:tʃənətli /

UK / ʌnˈfɔːrtʃənətli /

B1
  • adverb
  • In a way that is to be regretted; unluckily

fair

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US / feə(r) /

UK / fɛr /

A1
  • adjecitve
  • Neither very good nor very bad; average
  • (Of skin) light colored; not dark
  • Quite good; quite a lot
  • Treating all people the same way
  • (Of hair) light colored; blonde
  • (Of weather) sunny; not raining
  • noun
  • Event for companies to show their products
  • Event to sell things to help a charity

immune

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US / ɪˈmju:n /

UK / ɪˈmjoon /

B1
  • adjecitve
  • Having a special protection from, e.g. the law

also

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US / 'ɔ:lsəʊ /

UK / ˈɔlso /

A1
  • adverb
  • In addition; too; in a similar way

body

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US / ˈbɒd.i /

UK / ˈbɑdi /

A1
  • noun
  • An object distinct from other objects
  • A group of people involved in an activity together
  • Main part of something
  • A person's physical self

may

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US / meɪ /

UK / me /

A1
  • noun
  • 5th month of the year
  • other
  • Used to express a desire
  • Expresses permission, possibility or probability
  • Used to show that a thing could be true

level

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US / 'levl /

UK / ˈlɛvəl /

A2
  • adjecitve
  • (Sports) equal to another
  • Being steady and determined (e.g. a voice)
  • noun
  • Specific height of something
  • Amount of ability you have compared to others
  • Floor or deck within a building
  • Tool used to determine if something is lying flat
  • verb
  • To aim a gun at someone
  • To destroy a building; flatten an area completely
  • To make things flat or even
  • To make a score equal to another, in sports

order

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US / 'ɔ:də(r) /

UK / ˈɔrdɚ /

A1
  • noun
  • Religious or social group, as of nuns
  • Instructions to others to do what you want
  • State in which things are neat and organized
  • What you ask to buy, e.g. food in restaurant
  • Social or political control of an area
  • verb
  • To put things in a sequence, e.g. a, b, c
  • To give instructions to others to do what you want
  • To ask for something you want to buy, e.g. a meal

half

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US / hɑ:f /

UK / hæf, hɑf /

A1
  • adjecitve
  • Not complete
  • adverb
  • Partly; somewhat
  • noun
  • One of two equal periods of game time in a sport
  • The part you get when one is divided into two;

one

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US / wʌn /

UK / wʌn /

A1
  • pronoun
  • You; we; people in general; someone
  • The thing or person previously referred to
  • adjecitve
  • Used to refer to people generally
  • Being a strong example of (something mentioned)
  • number
  • Number 1

make

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US / meɪk /

UK / mek /

A1
  • noun
  • Product made by a particular company; brand
  • verb
  • To arrange or prepare something e.g. dinner
  • To get to (a place) on time
  • To gain the status of (teacher, lawyer, etc.)
  • To create something by putting things together
  • To earn a certain amount of money at a job
  • To cause or force a person to do something
  • To cause something to happen or be formed

patient

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US / 'peɪʃnt /

UK / ˈpeʃənt /

A2
  • adjecitve
  • Not getting annoyed when things take a long time
  • noun
  • Person who receives medical treatment or care

alone

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US / ə'ləʊn /

UK / əˈlon /

A1
  • adjecitve
  • Apart from others
  • Without equal
  • adverb
  • Without anyone or anything else

term

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US / tɜ:m /

UK / tɚm /

A1
  • noun
  • Conditions applying to an agreement, contract
  • Length of time something is expected to happen
  • Fixed period of weeks for learning at school
  • The (precise) name given to something
  • verb
  • To call; give a name to

less

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US / les /

UK / lɛs /

A1
  • adjecitve
  • Smaller in amount or degree
  • adverb
  • To a smaller degree
  • noun
  • A smaller amount
  • preposition
  • With the subtraction of

big

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US / bɪɡ /

UK / bɪɡ /

A1
  • adjecitve
  • Popular
  • Serious
  • Large

into

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US / 'ɪntə /

UK / ˈɪntu /

A1
  • preposition
  • Moving or going inside something
  • In the same direction as; in the direction of
  • So as to become; taking the state of

genetic

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US / dʒəˈnetɪk /

UK / dʒəˈnɛtɪk /

B1
  • adjecitve
  • Of, relating to, or controlled by genes

identify

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US / aɪ'dentɪfaɪ /

UK / aɪˈdɛntəˌfaɪ /

B1
  • verb
  • To indicate who or what someone or something is

person

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US / 'pɜ:sn /

UK / 'pɜ:rsn /

A1
  • noun
  • Man, woman or child

preemptive

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US / prɪ'emptɪv /

UK / pri:'emptɪv /

B1
  • adjecitve
  • Acting so as to prevent bad things happening

other

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US / 'ʌðə(r) /

UK / ˈʌðər /

A1
  • adjecitve
  • A thing different from that mentioned
  • determiner
  • (Something) else; not the first (one)
  • pronoun
  • Being the one and only thing of that category

chemical

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US / ˈkemɪkl /

UK / ˈkɛmɪkəl /

A2
  • adjecitve
  • Made of various elements
  • noun
  • Basic substance produced by mixing elements

miserable

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US / ˈmɪzrəbl /

UK / ˈmɪzərəbəl, ˈmɪzrə- /

A2
  • adjecitve
  • Very unhappy

than

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US / ðən /

UK / ðən /

A1
  • conjunction
  • Used to compare two things that are not equal

ridiculously

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US / rɪ'dɪkjələslɪ /

UK / rɪˈdɪkjələslɪ /

B1
  • adverb
  • Extremely; so much so that people might laugh

deep

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US / di:p /

UK / dip /

A1
  • adjecitve
  • Complex and important
  • Extreme or intense
  • Going far down from the surface
  • Low in pitch, as a sound
  • adverb
  • At a certain distance beneath the surface

subscription

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US / səbˈskrɪpʃn /

UK / səbˈskrɪpʃən /

B1
  • noun
  • Regular payment for a service, magazine etc.

develop

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US / dɪ'veləp /

UK / dɪˈvɛləp /

A1
  • verb
  • To explain something in steps and in detail
  • To create or think of something
  • To grow bigger, more complex, or more advanced
  • To make a photograph from film

gene

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US / dʒi:n /

UK / dʒin /

B1
  • noun
  • Part of cell controlling development of a thing

countless

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US / ˈkaʊntləs /

UK / ˈkaʊntlɪs /

B1
  • adjecitve
  • Being too many to be numbered or imagined

try

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US / traɪ /

UK / traɪ /

A1
  • noun
  • Act of putting the ball over the rugby goal line
  • verb
  • To make an effort, to attempt to do something
  • To examine someone or something in a court of law
  • To test to see if it is good or you like it
  • To make a person go through hardship; test
  • To examine something to see if it works

million

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US / ˈmɪljən /

UK / ˈmɪljən /

A1
  • number
  • 1,000,000

publish

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US / 'pʌblɪʃ /

UK / ˈpʌblɪʃ /

A2
  • verb
  • To prepare and make available a book magazine etc.
  • To release information to the general public

tool

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US / tu:l /

UK / tul /

A2
  • noun
  • Device used to make things, e.g. a hammer
  • verb
  • To provide a workshop with the right equipment

side

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US / saɪd /

UK / saɪd /

A1
  • adjecitve
  • In addition to the central or most important thing
  • Next to, or very close to, the right or left of
  • noun
  • Position or opinion that is opposite to another
  • Right or left part of a person's body
  • Feature of someone's personality
  • Straight edge of an object
  • One of two or more groups fighting each other
  • verb
  • To decide to agree with one point, not the other

after

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US / 'ɑ:ftə(r) /

UK / ˈæftɚ /

A1
  • adverb
  • Later than another time, or behind something
  • conjunction
  • Following something before
  • preposition
  • When an event happened or time has passed

tamoxifen

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US / təˈmɒksɪfen /

UK / təˈmɑːksɪfen /

A1
  • adjecitve

stick

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US / stɪk /

UK / stɪk /

A2
  • noun
  • Long thin piece of wood from a tree
  • verb
  • To push a sharp or pointed object into something
  • To join together using glue or paste
  • To remain in one place or position for a long time

too

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US / tu: /

UK / tu /

A1
  • adverb
  • In addition, also; with emphasis
  • Say that something is more than you want

feel

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US / fi:l /

UK / fil /

A1
  • verb
  • To be aware of or experience an emotion, sensation
  • To sense through direct contact; touch

will

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US / wɪl /

UK / wɪl /

A1
  • noun
  • Desire or choice of someone
  • Document saying who gets your money when you die
  • Strong desire to do something; determination
  • Desire to do something; strong wish to do
  • other
  • Used with verbs to express the future
  • verb
  • To leave property to someone after your death
  • To use mental effort to make something happen
  • Am (is, are) likely to do
  • To influence someone to do something
  • To make something happen by strongly wanting it

collateral

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US / kəˈlætərəl /

UK / kəˈlætərəl /

C1
  • noun
  • Property you offer as security against a loan

science

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US / 'saɪəns /

UK / ˈsaɪəns /

A2
  • noun
  • Study of the physical world, based on facts

grateful

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US / ˈgreɪtfl /

UK / ˈɡretfəl /

B1
  • adjecitve
  • Feeling or showing thanks; thankful

exactly

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US / ɪgˈzæktli /

UK / ɪɡˈzæktli /

A1
  • adverb
  • No more and no less than; precisely

many

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US / 'menɪ /

UK / ˈmɛni /

A1
  • determiner
  • Used to refer a large number of things

here

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US / hɪə(r) /

UK / hɪr /

A1
  • adverb
  • In this place; at this location, position or time

area

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US / 'eərɪə /

UK / ˈɛriə /

A1
  • noun
  • Amount of measured space
  • A specific section or space; part of a region
  • A subject or field of study

use

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US / ju:s /

UK / ju:s /

A1
  • noun
  • Ability to employ something
  • Need to enable it to work
  • Permission to do something with something
  • Act of spending money
  • Operation of a machine for its function
  • verb
  • To have; to eat, drink, consume etc.
  • To need to operate or work
  • To operate a machine, e.g. a computer
  • To treat a person badly
  • To do something with, for a task or purpose

walk

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US / wɔ:k /

UK / wɔk /

A1
  • noun
  • Journey on foot done for pleasure or exercise
  • verb
  • To move with your legs at a slowish pace

normal

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US / 'nɔ:ml /

UK / ˈnɔrməl /

A1
  • adjecitve
  • Standard or regular way of doing something
  • Having standard mental or physical ability, health

while

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US / waɪl /

UK / hwaɪl, waɪl /

A1
  • conjunction
  • In spite of the fact that; although
  • During the time that; at the same time
  • noun
  • Short amount of time

basic

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US / 'beɪsɪk /

UK / ˈbesɪk /

A1
  • adjecitve
  • At the most important or easiest (beginner) level

certain

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US / ˈsə:tn /

UK / ˈsɚtn /

A1
  • adjecitve
  • Definite, fixed
  • Referring to an unspecified amount or quantity
  • Being sure about something; without doubt

respond

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US / rɪ'spɒnd /

UK / rɪˈspɑnd /

A2
  • verb
  • To answer something or someone
  • To have a good reaction to e.g. medical treatment

thousand

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US / ˈθaʊznd /

UK / ˈθaʊzənd /

A1
  • number
  • Number 1,000

strategy

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US / 'strætədʒɪ /

UK / ˈstrætədʒi /

A2
  • noun
  • Careful plan or method for achieving a goal
  • other
  • Branch of military dealing with command

drug

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US / drʌɡ /

UK / drʌɡ /

A2
  • noun
  • Illegal substance taken for effect on the mind
  • Chemical used as a medicine
  • verb
  • To give drugs to someone to make them sleep

processes

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US / ˈprəʊsesɪz , prəˈsesɪz /

UK / ˈprɑːsesɪz , prəˈsesɪz /

B1
  • other
  • Sets of changes that occur slowly and naturally
  • verb
  • To organize and use data in a computer
  • To deal with official forms in the way required
  • To prepare by treating something in a certain way
  • To adopt a set of actions that produce a result
  • To convert by putting something through a machine

ever

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US / 'evə(r) /

UK / ˈɛvɚ /

A1
  • adverb
  • At any time; at all times in the future

once

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US / wʌns /

UK / wʌns /

A1
  • adverb
  • One time; one instance
  • At a time in the past
  • conjunction
  • When; as soon as

plus

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US / plʌs /

UK / plʌs /

A2
  • noun
  • A benefit or advantage
  • preposition
  • In addition; add
  • In addition to; Indicates a number above
  • Having a value greater than zero

combine

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US / kəmˈbaɪn /

UK / kəmˈbaɪn /

A2
  • verb
  • To mix several things together to form one thing

actually

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US / ˈæktʃuəli /

UK / ˈæktʃuəli /

A1
  • adverb
  • Used to add new (often different) information

skill

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US / skɪl /

UK / skɪl /

A2
  • noun
  • Ability to do something well

balance

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US / ˈbæləns /

UK / ˈbæləns /

A2
  • noun
  • Instrument for weighing things
  • Being stable; having equal weight on both sides
  • Money remaining after paying costs
  • verb
  • To be steady by having equal weight on both sides
  • To make two or more things equal

always

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US / 'ɔ:lweɪz /

UK / ˈɔlwez,-wɪz,-wiz /

A1
  • adverb
  • For a very long time
  • At all times; in every situation
  • For ever

new

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US / nju: /

UK / nu, nju /

A1
  • adjecitve
  • Not old, recently born, built or made
  • Being or doing something for the first time
  • Not felt, seen or known previously
  • Having been recently bought or obtained

stem

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US / stem /

UK / stɛm /

B1
  • noun
  • Long thin central part of a plant, bearing leaves
  • Long thin part supporting something e.g. a light
  • Main part of a word, e.g. 'use' in 'useful'
  • verb
  • To remove the stem of a flower or fruit
  • To start from or be the origin of
  • To stop something bad from spreading or developing

healthy

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US / ˈhelθi /

UK / ˈhɛlθi /

A1
  • adjecitve
  • In good condition physically, or financially; well

small

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US / smɔ:l /

UK / smɔl /

A1
  • adjecitve
  • Little in size; not big
  • (Of letters) not written in capital letters
  • Being insignificant or minor
  • (Of a business) with few people or things; local
  • (Of voice) being soft and quiet
  • (Of a child) being young

divide

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US / dɪ'vaɪd /

UK / dɪˈvaɪd /

A2
  • verb
  • To split numbers by another number, e.g. 6 / 2 = 3
  • To separate something into equal pieces

either

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US / ˈaɪðə(r) /

UK / ˈiðɚ, ˈaɪðɚ /

A1
  • adjecitve
  • One of two (used when there is a choice of two)
  • adverb
  • (After negative statements) likewise, in addition
  • conjunction
  • Used as the first of two connected things
  • determiner
  • Used as the first of two connected things
  • pronoun
  • The one or the other

mean

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US / mi:n /

UK / min /

A1
  • adjecitve
  • Being good at
  • Nasty; unkind
  • Not liking to spend money; cheap; stingy
  • noun
  • Average of a set of numbers
  • verb
  • To express a particular idea or thought
  • To intend to do something in particular
  • To have a particular meaning or value

like

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US / laɪk /

UK / laɪk /

A1
  • adjecitve
  • Being equal in status or kind to something else
  • Similar; the same
  • adverb
  • For example
  • preposition
  • Used as a filler; used to ad emphasis
  • In a way similar to the way something is done
  • Such as; for example
  • verb
  • To want to
  • To find something pleasing; to prefer something

shrink

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US / ʃrɪŋk /

UK / ʃrɪŋk /

B1
  • noun
  • A rude name for a psychiatrist
  • other
  • To make something smaller than it was before
  • verb
  • To become smaller
  • To make or become smaller than it was before

find

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US / faɪnd /

UK / faɪnd /

A1
  • noun
  • Object discovered by chance
  • Things that have been discovered from searching
  • verb
  • To become aware of something that is happening
  • To discover or meet by chance
  • To decide if someone is guilty of a crime, or not
  • To learn through study, research, or effort
  • To discover something by looking for it

happen

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US / 'hæpən /

UK / ˈhæpən /

A1
  • verb
  • To take place or occur

even

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US / 'i:vn /

UK / ˈivən /

A1
  • adjecitve
  • Being equal in influence, power, possibility etc.
  • Being divided equally or fairly
  • (Of teams/contest) with similar chances of success
  • Smooth, level, or regular
  • Can be divided by 2; ending in 2, 4, 6, 8, or 0
  • At a regular, equally steady manner
  • Remaining steady and unchanging
  • adverb
  • (When this is surprising) as well; too
  • (Used to compare two things/stress the difference)
  • verb
  • To make something level; to flatten
  • To make something equal

fancy

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US / 'fænsɪ /

UK / ˈfænsi /

A2
  • adjecitve
  • Unusual and attractive in design
  • verb
  • To want to have or do something; feel like
  • To imagine or suppose that something will happen
  • To believe or imagine something that is not true

suck

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US / sʌk /

UK / sʌk /

B1
  • noun
  • Drawing of liquid into a tube or hole
  • phrasal verb
  • To trick or deceive someone into doing something
  • verb
  • To be very bad, undesirable or unpleasant
  • To be very bad, undesirable, or unpleasant
  • To pull or remove something with great power
  • To attract someone; make someone interested
  • To draw into your mouth through a small hole

similar

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US / ˈsɪmələ(r) /

UK / ˈsɪməlɚ /

A1
  • adjecitve
  • Nearly the same; alike

vein

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US / veɪn /

UK / ven /

B1
  • noun
  • Tube that returns blood from the body to the heart
  • Mood or particular turn of mind
  • Thin line of something that has a different color

example

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US / ɪgˈzɑ:mpl /

UK / ɪɡˈzæmpəl /

A1
  • noun
  • Thing, person which represents a category

shut

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US / ʃʌt /

UK / ʃʌt /

A2
  • verb
  • To stop being open for business
  • To close something, e.g. a door

solve

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US / sɒlv /

UK / sɑ:lv /

A2
  • verb
  • To figure out a way to handle a difficult problem

leukaemia

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US / luːˈkiːmiə /

UK / luːˈkiːmiə /

B2
  • noun
  • Blood cancer in which white blood cells increase

get

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US / ɡet /

UK / ɡɛt /

A1
  • verb
  • To become affected by illness or disease
  • To begin to feel or understand an emotion or idea
  • To send or bring someone or something home, etc.
  • To go somewhere to obtain something
  • To (cause to) do a particular thing
  • To obtain, receive or be given something
  • To currently have
  • To prepare for use
  • To understand something being said or read

cell

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US / sel /

UK / sɛl /

A2
  • noun
  • Smallest unit of living things in biology
  • Group of people - often from a secret organization
  • Prisoner's room in a jail
  • Shortened form of 'cellphone'

storey

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US / 'stɔ:rɪ /

UK / ˈstɔri, ˈstori /

B1
  • noun
  • One of many floors or levels in a building

aware

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US / əˈwɛə /

UK / əˈwɛr /

A2
  • adjecitve
  • Knowing or feeling that something exists

tell

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US / tel /

UK / tɛl /

A1
  • verb
  • To (strongly) advise a person to do something
  • To be able to guess
  • To say or communicate information to someone
  • To inform, but without speaking; indicate
  • To have a negative effect on someone
  • To order someone to do something; command
  • To recognize something based on certain signs
  • To report something to an authority
  • To explain something or teach someone something

lesson

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US / 'lesn /

UK / ˈlɛsən /

A1
  • noun
  • Something done to learn or teach something; class
  • Wisdom or knowledge received from an experience

down

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US / daʊn /

UK / daʊn /

A1
  • adjecitve
  • Being sad, sick, or unhappy
  • Not operating, working, or functioning as expected
  • adverb
  • In a sitting or lying position
  • Towards or on the ground, floor, or bottom
  • Written or copied onto a piece of paper or book
  • noun
  • A period of play in American Football
  • The soft, smooth hairs that cover a bird's body
  • preposition
  • Along something's path, course, or direction
  • Going from a higher position to a lower position
  • verb
  • To eat or drink very quickly and without stopping

stratosphere

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US / ˈstrætəsfɪə(r) /

UK / ˈstrætəˌsfɪr /

A1
  • noun
  • Layer of Earth's atmosphere

different

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US / ˈdɪfrənt /

UK / ˈdɪfrənt /

A1
  • adjecitve
  • Not of the same kind; unlike other things

type

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US / taɪp /

UK / taɪp /

A1
  • noun
  • Printed letters or blocks used for printing them
  • Group of things or people sharing common features
  • verb
  • To identify something belonging to a group
  • To write by touching keys on a keyboard

own

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US / əʊn /

UK / on /

A1
  • adjecitve
  • Belong to oneself
  • determiner
  • Yours, his, hers, etc.; not belonging to another
  • pronoun
  • (Something) belong to myself
  • verb
  • To have something as your property

least

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US / li:st /

UK / list /

A1
  • adverb
  • In the smallest or lowest way
  • noun
  • Something that is of the lowest or smallest degree

block

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US / blɒk /

UK / blɑk /

A2
  • noun
  • Solid piece of material used for building
  • A piece of wood, chocolate etc.
  • Hard piece of wood, stone etc. with straight edges
  • Building made up of offices or apartments
  • Area of a city divided by four streets
  • verb
  • To stop from going forward or making progress

tend

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US / tend /

UK / tɛnd /

A2
  • verb
  • To move or act in a certain manner
  • To take care of
  • To regularly behave in a certain way

everywhere

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US / ˈevriweə(r) /

UK / ˈevriwer /

A1
  • adverb
  • Every place

about

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US / ə'baʊt /

UK / əˈbaʊt /

A1
  • adverb
  • To be ready to; going to
  • Nearly; approximately; roughly
  • Near; next to; close to
  • In every direction; in the area of
  • preposition
  • Concerning or of (a topic)

dna

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US / ˌdiː en ˈeɪ /

UK / ˌdiː en ˈeɪ /

B2
  • noun
  • Chemical in living cells with genetic information

quadratic

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US / kwɒˈdrætɪk /

UK / kwɑˈdrætɪk /

A1
  • adjecitve
  • Polynomial of the second degree

detangle

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US / /

UK / /

A1
  • transitive verb
  • Remove tangles from (hair)

recruit

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US / rɪ'kru:t /

UK / rɪˈkrut /

B1
  • noun
  • Person who has just joined the military
  • Person who has just begun a new activity or job
  • verb
  • To convince and help people to join the military
  • To find new employees, volunteers or members
  • To find people to join an organization or business

annual

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US / ˈænjuəl /

UK / ˈænjuəl /

A2
  • adjecitve
  • Happening once a year, or every year
  • noun
  • Book (in a series) released each year

absolutely

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US / ˈæbsəlu:tli /

UK / ˈæbsəˌlutli, ˌæbsəˈlutli /

A2
  • adverb
  • Completely; totally; very

right

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US / raɪt /

UK / raɪt /

A1
  • adjecitve
  • Correct or true
  • The south side of you looking at the rising sun
  • adverb
  • Exactly in a place or time
  • Being appropriate for a particular event
  • In a straight or direct manner
  • noun
  • Something you are legally or morally allowed to do
  • Ideal of what is just and good
  • Political view based on conservatism
  • verb
  • To fix something previously wrong or unjust
  • To make upright, as a boat that has turned over

people

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US / 'pi:pl /

UK / ˈpipəl /

A1
  • noun
  • Persons sharing culture, country, background, etc.
  • Men, Women, Children

similarly

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US / ˈsɪmələli /

UK / ˈsɪmələrli /

A2
  • adverb
  • In a way almost the same as something else

poison

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US / ˈpɔɪzn /

UK / ˈpɔɪzən /

A2
  • noun
  • Substance that can kill when eaten/drunk
  • verb
  • To affect something in a very negative way
  • To hurt or kill with a dangerous substance

hard

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US / hɑ:d /

UK / hɑː(r)d /

A1
  • adjecitve
  • Difficult to do; difficult to understand
  • (Of facts) not able to be misunderstood; clear
  • (Of alcohol) strong
  • Involving or requiring lots of work, effort, care
  • Being full of pain, trouble, and problems
  • Strong
  • (Of edge) clear; sharp
  • Difficult to bend, break or cut; solid
  • adverb
  • With lots of force, power, or impact

supercharge

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US / /

UK / /

C2
  • verb
  • To add an oxygen compressor to an engine

forewarn

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US / fɔːˈwɔːn /

UK / fɔːrˈwɔːrn /

C2
  • verb
  • To warn or give early warning in advance

tumour

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US / ˈtju:mə(r) /

UK / ˈtuːmər /

B1
  • noun
  • Abnormal growth of cells; cancer

growth

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US / grəʊθ /

UK / groʊθ /

A2
  • noun
  • Improvement, development in a skill over time
  • A mass on the skin or body part related to illness
  • Act of growing

impact

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US / 'ɪmpækt /

UK / ˈɪmˌpækt /

A2
  • noun
  • A striking effect or result to hit with force
  • Very strong influence
  • Act or force of one thing hitting something else
  • verb
  • To hit or strike someone or something with force

place

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US / pleɪs /

UK / ples /

A1
  • noun
  • Particular location, area or region
  • verb
  • To put someone in a particular type of situation
  • To put something in a certain location or position

then

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US / ðen /

UK / ðɛn /

A1
  • adverb
  • A time that is not now
  • Following another thing in time or arrangement
  • Following on reasonably from what was just stated
  • At that time, not now

courtesy

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US / ˈkɜ:təsi /

UK / ˈkɜ:rtəsi /

B2
  • noun
  • Polite and respectful behavior

fight

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US / faɪt /

UK / faɪt /

A1
  • noun
  • An argument or quarrel
  • Act of trying to hurt someone by hitting them
  • A struggle to do a difficult task
  • verb
  • To argue or quarrel with someone about something
  • To try to hurt someone by hitting them
  • To struggle to do a difficult task

method

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US / 'meθəd /

UK / ˈmɛθəd /

A2
  • noun
  • (Organized and planned) way of doing something

estrogen

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US / 'i:strədʒən /

UK / ˈɛstrədʒən /

A1
  • noun
  • General term for female steroid sex hormones that are secreted by the ovary and responsible for typi

that

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US / ðæt /

UK / ðæt, ðət /

A1
  • adjecitve
  • The person or thing being talked about
  • Used to identify something both the speakers know
  • adverb
  • Used to reinforce adjectives and adverbs
  • To such a degree
  • conjunction
  • Used to connect a noun clause
  • Used to introduce an adverbial clause
  • Used to introduce a noun clause
  • determiner
  • Used as a noun to refer to something
  • pronoun
  • Referring an object far away
  • Used to refer to the relative pronoun ‘which’

give

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US / ɡɪv /

UK / ɡɪv /

A1
  • noun
  • Degree of flexibility in something, a material
  • verb
  • To hand over or present something to someone
  • To cause someone to have or experience something

category

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US / ˈkætəgəri /

UK / ˈkætɪˌɡɔri, -ˌɡori /

B1
  • noun
  • Groups of things that are similar in some way

our

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US / 'aʊə(r) /

UK / aʊr /

A1
  • determiner
  • Belonging to us

research

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US / rɪ'sɜ:tʃ /

UK / rɪˈsɚtʃ, ˈriˌsɚtʃ /

A2
  • noun
  • Study done to discover new ideas and facts
  • Work done to find or discover knowledge
  • verb
  • To study in order to discover new ideas and facts

same

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US / seɪm /

UK / sem /

A1
  • adjecitve
  • Being equal in quality and amount
  • Identical; not different
  • Not changing; constant

neat

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US / ni:t /

UK / nit /

A2
  • adjecitve
  • That you approve of; cool
  • (Of alcohol) not weakened with water or a mixer
  • Not messy; clean and orderly; simple and effective

now

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US / naʊ /

UK / naʊ /

A1
  • adverb
  • At the present time or moment
  • Right away or in the next possible moment
  • Used to refer to something that just happened
  • Time between the present and a moment in the past
  • conjunction
  • Resulting from or because of something

deliver

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US / dɪ'lɪvə(r) /

UK / dɪˈlɪvɚ /

A2
  • verb
  • To give birth to a child; help a woman give birth
  • To save someone from a problem or crisis
  • To keep a promise; do what you say you would
  • To present something to a group, as a speech
  • To take something to a person or place

effect

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US / ɪ'fekt /

UK / ɪˈfɛkt /

A1
  • noun
  • An advantage, benefit
  • Change brought about by a cause; result

but

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US / bət /

UK / bʌt,bət /

A1
  • conjunction
  • Used before you say something different, opposite

aspirin

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US / 'æsprɪn /

UK / ˈæspərɪn, -prɪn /

B2
  • noun
  • Medicine used to treat pain and fever

life

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US / laɪf /

UK / laɪf /

A1
  • noun
  • All the living things e.g. animals, plants, humans
  • Period of time things live, from birth to death

experience

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US / ɪk'spɪərɪəns /

UK / ɪkˈspɪriəns /

A1
  • noun
  • Thing a person has done or that happened to them
  • An event at which you learned something
  • Knowledge gained by living life, doing new things
  • verb
  • To gain knowledge by doing things

currently

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US / ˈkʌrəntli /

UK / ˈkʌrənt(ə)li /

A2
  • adverb
  • Happening or being in the present time

video

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US / 'vɪdɪəʊ /

UK / ˈvɪdiˌo /

A2
  • adjecitve
  • Of a moving film, with sound
  • noun
  • Recording capturing action with sound
  • verb
  • To make a moving film of, with sound

especially

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US / ɪˈspeʃəli /

UK / ɛˈspɛʃəli, ɪˈspɛʃ- /

A1
  • adverb
  • More than usual; extremely

forearm

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US / 'fɔ:rɑ:m /

UK / fɔrˈɑrm, for- /

C1
  • noun
  • Lower part of your arm attached to your hand

towards

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US / tə'wɔ:dz /

UK / 'təuədz, twɔ:dz /

A1
  • preposition
  • In the direction of someone or something

platform

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US / 'plætfɔ:m /

UK / ˈplætˌfɔrm /

B1
  • noun
  • Flat, raised structure that people stand on
  • Area from which you board a train at a station

good

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US / ɡʊd /

UK / ɡʊd /

A1
  • adjecitve
  • Proper, appropriate or right
  • (Of an amount) enough; plenty
  • Excellent; high quality
  • Acting well or properly; of moral character
  • In a positive or happy emotional state
  • noun
  • Advantage or benefit

understand

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US / ˌʌndə'stænd /

UK / ˌʌndɚˈstænd /

A1
  • verb
  • To know the meaning of language, what someone says

size

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US / saɪz /

UK / saɪz /

A1
  • noun
  • How big or small a thing is
  • Standard measurements for clothing, shoes
  • verb
  • To make something to fit a particular measurement
  • To organize or group from small to large

not

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US / nɒt /

UK / nɑt /

A1
  • adverb
  • Word indicating the negative
  • (Used to form the negative of verbs)

trial

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US / ˈtraɪəl /

UK / ˈtraɪəl, traɪl /

A2
  • adjecitve
  • Being made or done as a test or experiment
  • noun
  • Hearing and judgment of a case in court
  • Act or process of testing or experimenting
  • verb
  • To be made or done as a test or experiment

disease

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US / dɪˈzi:z /

UK / dɪˈziz /

A2
  • noun
  • Illness that affects a person, animal, or plant

attach

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US / ə'tætʃ /

UK / əˈtætʃ /

A2
  • verb
  • To be associated or connected with

would

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US / wʊd /

UK / wʊd /

A1
  • other
  • Used to indicate something imagined
  • Used to ask or request something politely
  • Verb used to indicate possibility, request etc.
  • Used to indicate a preference
  • Used to indicate a reaction
  • Indicates something that occurred repeatedly
  • Used to indicate willingness or ability to do

stomach

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US / 'stʌmək /

UK / ˈstʌmək /

A2
  • noun
  • Place in the body where food is processed
  • verb
  • to be able to accept something unpleasant

signal

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US / 'sɪɡnəl /

UK / ˈsɪɡnəl /

A2
  • adjecitve
  • Most important or most noticeable
  • noun
  • Movement of a hand or other means to send messages
  • Act/sound that tells people to do/start something
  • Road-side lights that direct traffic to go or stop
  • Sound and light waves carrying TV and radio data
  • verb
  • To be evidence/an indication something will happen
  • To make a noise or motion to tell someone to start

want

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US / wɔnt /

UK / wɑnt, wɔnt /

A1
  • noun
  • Something you desire or wish for
  • State or condition of poverty
  • verb
  • To desire or wish for something; hope for a thing

can

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US / kæn /

UK / kən,kæn /

A1
  • noun
  • A metal container for storing food
  • other
  • Able to; have the skill to; have the time to
  • verb
  • To have permission to
  • To be possible to do
  • To preserve food by sealing it in a metal container

description

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US / dɪˈskrɪpʃn /

UK / dɪˈskrɪpʃən /

A2
  • noun
  • Explanation of what something is like, looks like

generally

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US / /

UK / /

A2
  • adverb
  • Usually; as a rule; by, to or for most people

brilliant

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US / 'brɪlɪənt /

UK / ˈbrɪljənt /

A2
  • adjecitve
  • Having a great amount of intelligence or talent
  • Being very bright, like a diamond; shining

quiver

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US / 'kwɪvə(r) /

UK / ˈkwɪvɚ /

B2
  • noun
  • Container for arrows, worn across the back
  • verb
  • To shake with a slight, rapid, trembling movement

support

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US / səˈpɔ:t /

UK / səˈpɔrt, -ˈport /

A1
  • noun
  • Assistance or advice given to someone
  • Evidence that helps prove something is true
  • A thing to hold up or prevent from falling down
  • verb
  • To give assistance or advice to someone
  • To help prove or show that something is true
  • To hold up or prevent from falling down

follicle

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US / ˈfɒlɪkl /

UK / ˈfɑlɪkəl /

C1
  • noun
  • Small spherical group of cells containing a cavity

protein

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US / ˈprəʊti:n /

UK / ˈprəʊˌtiːn /

B1
  • noun
  • Group of molecules made from amino acids

feeling

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US / ˈfi:lɪŋ /

UK / ˈfilɪŋ /

A1
  • noun
  • Sensation or emotion you experience
  • verb
  • To be aware of or experience an emotion, sensation
  • To sense through direct contact; touch

online

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US / ˌɒnˈlaɪn /

UK / ˌɑ:nˈlaɪn /

B1
  • adjecitve
  • Connected to the internet

whether

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US / ˈweðə(r) /

UK / ˈhwɛðɚ, ˈwɛð- /

A1
  • conjunction
  • If something will happen or not

slash

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US / slæʃ /

UK / slæʃ /

B2
  • noun
  • Line ( / ) used in writing
  • Long, deep cut, caused by a sharp object
  • verb
  • To cut violently with a sharp object
  • To decrease something by a large amount

help

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US / help /

UK / hɛlp /

A1
  • noun
  • Something given to enable a person to do something
  • Assistance given to someone in need
  • Someone who makes something easier or possible
  • verb
  • To act to enable a person to do something; assist
  • To make something better or less difficult

call

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US / kɔ:l /

UK / kɔl /

A1
  • noun
  • A order or request for action
  • The sound an animal makes, often when in danger
  • A correct prediction, e.g. a decision in a game
  • A short visit to a place or person
  • A decision by a referee or umpire in a game
  • verb
  • To make a request or order for action
  • (Animal) to make sounds to warn of danger
  • To announce the date of an election
  • To make a judgment about something
  • To give someone or something a name
  • To guess in advance the result or outcome
  • To visit a place or person for a short time
  • To phone someone
  • To speak, announce or shout in a loud voice

keep

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US / ki:p /

UK / kip /

A1
  • noun
  • Large, strong tower in the middle of a castle
  • Money spent on you so you can live in a place
  • verb
  • To continue doing something; not to stop
  • To stop balls going in a goal in sports
  • To not give back or return something
  • (Of food) to not spoil or not rot
  • To take possession of something to own, e.g. a pet
  • To have and continue to hold something
  • To do something that you have promised or agreed
  • To stay in a certain place or condition
  • To maintain the rules

another

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US / əˈnʌðə(r) /

UK / əˈnʌðɚ /

A1
  • adjecitve
  • One more, but not this
  • determiner
  • One more added
  • pronoun
  • One more (thing)

mess

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US / mes /

UK / mɛs /

A2
  • noun
  • Something that is untidy, dirty or unclean
  • verb
  • To make something untidy or dirty

particular

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US / pəˈtɪkjələ(r) /

UK / pɚˈtɪkjəlɚ, pəˈtɪk- /

B2
  • adjecitve
  • One specific (one)
  • Having firm ideas about what is desirable
  • Being special or more than is typical

linear

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US / ˈlɪniə(r) /

UK / ˈlɪniər /

B1
  • adjecitve
  • Made of lines
  • Series of progressing from one stage to another

invader

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US / ɪnˈveɪdə(r) /

UK / ɪnˈvedɚ /

B1
  • noun
  • Someone who enters to cause harm

affect

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US / ə'fekt /

UK / əˈfɛkt /

A2
  • verb
  • To cause a change in something else

doctor

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US / ˈdɒktə(r) /

UK / ˈdɑːktɚ /

A1
  • noun
  • Person paid to help people become or stay healthy
  • Person awarded the highest university degree
  • verb
  • To treat someone's illness
  • To change something in order to trick someone

and

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US / ənd /

UK / ənd, ən,ænd /

A1
  • conjunction
  • Used to refer to two or more things
  • Plus; in addition; on top of that
  • Used to introduce an action that follows another

journal

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US / ˈdʒə:nl /

UK / ˈdʒɚnəl /

B1
  • noun
  • A diary; record of what you do every day
  • Magazine of academic papers

put

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US / pʊt /

UK / pʊt /

A1
  • phrasal verb
  • to make a light stop shining by pressing or moving a switch
  • verb
  • To move or place a thing in a particular position
  • To rate something in importance or value
  • To write or say something in a certain manner

flag

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US / flæɡ /

UK / flæɡ /

A2
  • noun
  • Piece of cloth representing a team, country etc.
  • verb
  • To indicate something should get special attention
  • To work, run etc. more slowly or with less power

two

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US / tu: /

UK / tu /

A1
  • number
  • 2

leave

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US / li:v /

UK / liv /

A1
  • noun
  • Permission to do something
  • Vacation time; time off work
  • verb
  • To go away from; depart
  • To gift property to someone after you die
  • To allow something to continue happening
  • To let something remain unused or available
  • To let something or someone remain somewhere

anything

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US / ˈeniθɪŋ /

UK / ˈɛniˌθɪŋ /

A1
  • pronoun
  • A thing of any kind

only

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US / ˈəunli /

UK / ˈonli /

A1
  • adverb
  • Just one; just that amount or thing; not more than
  • Not very important or serious
  • Just that type of thing, person
  • Short time ago; not before a certain time
  • conjunction
  • Except; but

any

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US / 'enɪ /

UK / ˈɛni /

A1
  • adjecitve
  • One, or some, no matter which
  • pronoun
  • One (thing) of many; some

something

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US / ˈsʌmθɪŋ /

UK / ˈsʌmθɪŋ /

A1
  • adverb
  • In some degree or measure
  • noun
  • a person or thing of some value or consequence
  • pronoun
  • Thing that is not yet known or named
  • Approximately

form

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US / fɔ:m /

UK / fɔrm /

A1
  • noun
  • Sports team or person's current winning record
  • Document you complete when making an application
  • Visible shape or style; type; kind
  • verb
  • To organize something such as a club or group
  • To develop; to come into a shape or substance
  • To make something into a particular shape

back

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US / bæk /

UK / bæk /

A1
  • adjecitve
  • Farthest from the front e.g. in a classroom
  • adverb
  • Have returned to a place you were before
  • noun
  • The part of a chair that the upper body leans upon
  • Location at the rear of something
  • The reverse of side something
  • Area on the rear of your body
  • verb
  • To bet money on something
  • To go backwards in a car
  • To support and encourage someone or some cause

baddie

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US / ˈbædi /

UK / ˈbædi /

C2
  • noun
  • Main bad character in a film or work of fiction

early

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US / ˈɜ:li /

UK / ˈɜ:rli /

A1
  • adjecitve
  • Happening or appearing before
  • adverb
  • Coming/happening before others in a time sequence
  • Happening sooner than expected

significantly

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US / sɪgˈnɪfɪkəntli /

UK / sɪɡˈnɪfəkəntlɪ /

A2
  • adverb
  • In a way that is important or noticeable
  • In a way that is meaningful

cancer

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US / 'kænsə(r) /

UK / ˈkænsɚ /

B1
  • noun
  • Any growth caused by abnormal cell division

from

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US / frəm /

UK / frʌm, frɑm,frəm /

A1
  • preposition
  • Starting at a particular place, time or level

major

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US / 'meɪdʒə(r) /

UK / ˈmedʒɚ /

A2
  • adjecitve
  • Main league; esp. referring to American baseball
  • Important, serious, or large in scope, size
  • noun
  • High-ranking officer in the army
  • Main subject you study at university
  • verb
  • To study a particular subject at university

most

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US / məʊst /

UK / most /

A1
  • adverb
  • Very; extremely
  • Greatest possible degree
  • pronoun
  • Nearly all of something

sometimes

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US / ˈsʌmtaɪmz /

UK / ˈsʌmˌtaɪmz /

A1
  • adverb
  • Only at certain times; occasionally

mostly

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US / ˈməʊstli /

UK / ˈmoʊstli /

A2
  • adverb
  • In large part; mainly or chiefly

sucker

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US / ˈsʌkə(r) /

UK / ˈsʌkɚ /

C1
  • noun
  • Part of an animal used for holding onto surfaces
  • Someone who is easily fooled

nucleus

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US / ˈnju:kliəs /

UK / ˈnu:kliəs /

B2
  • noun
  • Center of an atom
  • Control center of a cell
  • Most important part of something larger

rest

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US / rest /

UK / rɛst /

A1
  • noun
  • Time when one relaxes, sleeps, or is inactive
  • State in which there is a lack of motion
  • Part of something remaining after some was used
  • verb
  • To stop working or avoid activity to recover
  • (Of dead person) to lie in a grave
  • To lean, support or place something against
  • To not be tired because you had enough sleep

hair

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US / heə(r) /

UK / her /

A1
  • noun
  • Long thin strands growing on your head or body
  • Short distance; a very small amount

doxorubicin

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US / ˌdɒksəˈruːbəsɪn /

UK / ˌdɑːksəˈruːbɪsɪn /

A1
  • noun
  • Antibiotic used as an anticancer drug

come

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US / kʌm /

UK / kʌm /

A1
  • verb
  • To arrive at a place
  • (Of mail) to be delivered
  • To move toward someone; go with someone
  • To reach a certain point or state

version

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US / ˈvə:ʃən /

UK / ˈvɚʒən, -ʃən /

A2
  • noun
  • Different way that someone interprets something
  • New or different form of something
  • An updated form of some software

antibody

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US / ˈæntibɒdi /

UK / ˈæntibɑ:di /

B1
  • noun
  • Substance produced by the body to fight disease

lymphocytic

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US / ˌlɪmfəʊˈsɪtɪk /

UK / ˌlɪmfəˈsaɪtɪk /

A1
  • adjecitve
  • Concerning lymphocytes

out

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US / aʊt /

UK / aʊt /

A1
  • adverb
  • No longer stylish (e.g. fashion)
  • Away from home, business, or the usual place
  • In a direction/movement away from inside or center
  • noun
  • Act when a batter cannot continue playing
  • verb
  • To tell people a secret

normally

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US / ˈnɔ:məli /

UK / ˈnɔːrməli /

B1
  • adverb
  • In the manner that is usual or ordinary

hope

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US / həʊp /

UK / hop /

A1
  • noun
  • When you wish something will happen; what you wish
  • verb
  • To expect and want something to happen

screen

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US / skri:n /

UK / skrin /

A2
  • noun
  • Wire net in a door or window to keep insects out
  • Displays in a theater on which movies are shown
  • Flat surface on a computer or TV showing images
  • verb
  • To hide or block something from being seen
  • To examine to find something, e.g. best candidate

chemo

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US / ˈki:məʊ /

UK / ˈki:moʊ /

A1
  • noun
  • Chemotherapy.

beyond

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US / bɪ'jɒnd /

UK / biˈɑnd, bɪˈjɑnd /

A2
  • adverb
  • On or to the farther side
  • In addition to
  • preposition
  • Later in time than
  • Out of the limits of

name

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US / neɪm /

UK / nem /

A1
  • noun
  • What something or someone is called
  • verb
  • To state what someone is called, e.g. John

familiar

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US / fəˈmɪliə(r) /

UK / fəˈmɪljɚ /

A2
  • adjecitve
  • Well-known or easily recognized

lot

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US / lɒt /

UK / lɑt /

A1
  • noun
  • What happens to a person in life from chance; fate
  • A group of people seen together
  • Item for sale at an auction
  • Small area of land used for a purpose e.g. parking

enzyme

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US / ˈenzaɪm /

UK / ˈɛnzaɪm /

B2
  • noun
  • A protein made by cells

surgery

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US / 'sɜ:dʒərɪ /

UK / ˈsɚdʒəri /

B1
  • noun
  • A doctor's office; health clinic
  • Medical operation involving cutting into body

completely

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US / kəmˈpli:tli /

UK / kəmˈpliːtli /

A1
  • adverb
  • In every way or as much as possible

visual

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US / 'vɪʒʊəl /

UK / ˈvɪʒuəl /

A2
  • adjecitve
  • Of or relating to vision
  • noun
  • Pictures/images used to help audience understand
  • Subtitles section
  • Thanks to Brilliant for supporting this SciShow video.
  • As a SciShow viewer, you can keep building your STEM skills with a 30-day free trial and 20% off an annual premium subscription at Brilliant.org slash SciShow.
  • Chemotherapy sucks.
  • By all accounts, it's basically poison.
  • It interferes with stuff in your own cells in the hopes that it will kill the cancer before it kills you.
  • While it works, and it definitely works, doctors generally aren't fond of putting patients through its gauntlet of side effects.
  • And they're actually making steady progress towards not doing that.
  • So here's a look at why we use chemo, some of the new options we can use instead, and how cancer treatment is getting better and smarter all the time.
  • To
  • Be absolutely clear, chemotherapy works.
  • That's why we use it so much.
  • At its most basic, chemotherapy, or chemo for short, is just using drugs to treat cancer.
  • Between 2013 and 2020, about one in five cancerous tumors in England — that is, more than half a million of us suckers — got treated with some form of chemotherapy.
  • One thing that's important to keep in mind is that chemo comes in many shapes and sizes.
  • There are hundreds of different cancer drugs out there, and patients will get one or a combination of different drugs depending on their circumstances.
  • Sometimes the idea is to make the cancer go away completely, while other times the chemo helps to make other treatments, like surgery, more effective.
  • And sometimes the goal is to simply manage symptoms when a cure isn't possible.
  • But cures do happen.
  • Newly diagnosed Hodgkin lymphoma, testicular cancer, and acute lymphocytic leukemia can all be treated with chemotherapy, with the expectation that in most patients, the cancer goes away for good.
  • If you want an example that I am intimately familiar with, one common drug is called doxorubicin, which is sometimes combined with three other drugs with similarly difficult-to-pronounce names, into a cocktail called ABVD.
  • Without going too deep into it, doxorubicin is good at killing dividing cells.
  • Because normally, the nucleus is a tangled mess of DNA, and it uses an enzyme called topoisomerase as like a molecular detangling spray.
  • The cell needs to detangle its DNA in order to shrink down those neat little chromosomes and divide.
  • Which it can't do without its detangling spray, which doxorubicin blocks.
  • So that's why doxorubicin targets mostly cancer cells, but also can affect other cells that like to divide.
  • This is a common problem with chemo drugs.
  • We want to target the cancer cells.
  • Because cancer cells, on a molecular level, look very similar to the rest of you.
  • One thing almost all cancers have in common is that they grow and divide quickly.
  • So a lot of chemo drugs target various growth and division mechanisms.
  • Unfortunately, that means that they can do a fair amount of collateral damage, especially to cells that have to replicate a lot for their normal jobs, like growing hair, replacing the stomach lining,
  • Or creating immune cells.
  • So while I can tell you from personal experience that chemotherapy is miserable, it also has done amazing things for me personally, and I'm extremely grateful for all of the different drugs in ABVD.
  • But if we can do better, we like doing better.
  • There are at least two important avenues of research for better, less regular cell death-inducing treatments— targeted and personalized therapies.
  • Right now, most chemo drugs go in your arm or into your stomach, and then everywhere in your body.
  • Which is how they get to your stomach lining and hair follicles, etc.
  • But targeted therapies are designed to more specifically go after the cancer, leaving the non-cancerous cells alone.
  • Some of these are so-called small-molecule drugs that target different parts of a tumor's growth cycle.
  • The term refers to small molecules that you would recognize as similar to traditional drugs like aspirin or penicillin.
  • By interfering with molecular processes that only cancer cells have, they can spare a patient some of the harmful side effects of regular chemotherapy.
  • One of the earliest success stories in this space is a drug called imatinib, which is used for some leukemias.
  • These leukemias have a ridiculously specific mutation, known as BCR-ABL.
  • It happens when two different chromosomes get stuck together in one exact place, sending levels of a certain cellular growth signal into the stratosphere.
  • And that mutation is only in the cancer, and not in the patient's healthy cells.
  • Imatinib shuts that growth signal back down.
  • This method of stopping messages that are specific to a cancer is promising.
  • In fact, a 2018 review estimated about 150 drugs in the same vein as imatinib were in clinical trials, plus countless others that work in other ways.
  • But good small-molecule drugs are hard to make because you need to know a lot about the molecular processes of cancer that you are trying to treat.
  • And then, once you've got something that works for one cancer, there's no guarantee that it will work for even a slightly different disease.
  • Luckily, biology gives us an even better tool for targeting a specific thing.
  • Monoclonal antibodies are another major category of targeted therapy.
  • You may have noticed that a lot of newer cancer drugs have this fancy MAB suffix, like trastuzumab and pembrolizumab and rituximab.
  • These are all monoclonal antibodies.
  • They come to us courtesy of our own immune system.
  • They are those Y-shaped molecules that normally stick to viruses and other invaders.
  • But with a little science, we can convince them to stick to pretty much anything we'd like.
  • The monoclonal bit on the antibody just means all the ones given in a batch are the same and stick to the same thing.
  • In general, monoclonal antibodies do one of three things in cancer treatment.
  • They block cancer cells from growing, or they flag the cells to the immune system as baddies, or they deliver harmful chemicals into the cell.
  • Trastuzumab, for example, attaches to a protein found on some cancers called HER2.
  • When cancers have these proteins, they have a lot of them.
  • And they help the cancer grow and divide.
  • So by blocking them, trastuzumab stops this growth.
  • On the other hand, pembrolizumab is designed to attach to proteins on your immune cells and supercharge them to better identify and eliminate cancer cells.
  • Since this strategy recruits your immune system, it's also known as immunotherapy.
  • Now, another big area of research right now is in personalized therapy.
  • That's because no two cancers are exactly alike, and no two people have the exact same genetic background.
  • If you have a mutated version of the genes called BRCA1 or BRCA2, you are significantly more likely to develop breast cancer in your life.
  • It's now way easier and cheaper than it ever was before to test early on to find out if you're at risk because of your genetics.
  • Then, you can do something about it, either by just being more aware and then screening more often, or by choosing preemptive therapy.
  • More than that, knowing if you have these genes can also impact the best treatment for you if you do develop cancer.
  • For example, a big cancer drug trial published in the New England Journal of Medicine in 2021 found that cancers with BRCA1 or BRCA2 mutations are more susceptible to a type of drug called a PARP inhibitor.
  • And that's not all we can do to individualize treatment.
  • In fact, we don't even need to move beyond breast cancer for another example.
  • Some breast cancers have receptors for estrogen, and some don't.
  • Those with estrogen receptors respond to drugs that block them, like tamoxifen.
  • But those drugs won't work if your cancer doesn't have those receptors to begin with.
  • The same thing happens with receptors for progesterone, and also for HER2.
  • We have drugs to target any of the three.
  • A triple-negative breast cancer doesn't have any of those three receptors, and tends to be the hardest to treat.
  • On the flip side, though, we can do tests to find that out, and that can help doctors develop the patient's treatment plan.
  • Forewarned is forearmed.
  • If we can better understand, at a molecular level, not only the cancer, but the person it's growing in, we can use exactly the right drug in exactly the right place.
  • Chemotherapy is not going anywhere in the next 5, 10, or 20 years.
  • In fact, some targeted therapies just deliver the exact same old chemo drugs right to the tumor, like a little side effect-avoiding Uber driver.
  • But we're developing more, better arrows to have in our quiver to keep people not only alive, but feeling better.
  • And that is something to feel very good about.
  • Chemotherapy is always going to be a balance, but it's a system we currently have in place and understand pretty well.
  • And making new systems work can be a challenge, whether they're systems to fight cancer or solve mathematical problems.
  • That's why Brilliant has made a course to help make systems of equations a little more approachable.
  • Brilliant is an online learning platform with thousands of lessons in science, computer science, and math.
  • And this particular Brilliant course walks you through everything from linear systems to systems with quadratics.
  • With Brilliant, you'll learn in a new way.
  • This interactive course uses visual models and interactive graphing to show you how systems work, not just tell you about them.
  • And you can try it out at Brilliant.org slash SciShow, or in the link in the description down below.
  • That link also gives you a free 30-day trial and 20% off an annual Premium Brilliant subscription.
  • Thanks to Brilliant for supporting this SciShow video.
  • Transcribed by https://otter.ai