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Depression Treatment Resistance: Can Botox Be the Answer?

Video vocabulary

swallow

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US / 'swɒləʊ /

UK / ˈswɑː.loʊ /

A2
  • noun
  • Small northern bird with downward-pointing wings
  • Making food or drink go down to the stomach
  • verb
  • To believe (something that is not true)
  • To make food go from your mouth to your stomach
  • To cover or hide something

doctor

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US / ˈdɒktə(r) /

UK / ˈdɑːktɚ /

A1
  • noun
  • Person paid to help people become or stay healthy
  • Person awarded the highest university degree
  • verb
  • To treat someone's illness
  • To change something in order to trick someone

familiar

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US / fəˈmɪliə(r) /

UK / fəˈmɪljɚ /

A2
  • adjecitve
  • Well-known or easily recognized

keep

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US / ki:p /

UK / kip /

A1
  • noun
  • Large, strong tower in the middle of a castle
  • Money spent on you so you can live in a place
  • verb
  • To continue doing something; not to stop
  • To stop balls going in a goal in sports
  • To not give back or return something
  • (Of food) to not spoil or not rot
  • To take possession of something to own, e.g. a pet
  • To have and continue to hold something
  • To do something that you have promised or agreed
  • To stay in a certain place or condition
  • To maintain the rules

serotonin

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US / ˌserəˈtəʊnɪn /

UK / ˌserəˈtoʊnɪn /

A1
  • noun
  • Compound that is in blood

typically

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US / ˈtɪpɪkli /

UK / ˈtɪpɪklɪ /

B1
  • adverb
  • In a normal or usual way

antidepressant

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US / ˌæntidɪˈpresnt /

UK / ˌæntidɪˈprɛsənt, ˌæntaɪ- /

C2
  • noun
  • Medicine used to treat depression

double

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US / 'dʌbl /

UK / ˈdʌbəl /

A2
  • adjecitve
  • Concerning or intended for use by two people
  • Two times the amount or degree; twice
  • Made of two parts that are the same, similar
  • noun
  • Person that is exactly like someone else
  • verb
  • To be used for two functions at the same time
  • To make or become twice as much

far

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US / fɑ:(r) /

UK / fɑr /

A1
  • adjecitve
  • A long way away
  • Being a long way away
  • adverb
  • To a large degree or extent

reduce

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US / rɪ'dju:s /

UK / rɪˈdus, -ˈdjus /

A2
  • verb
  • To try to decrease, e.g. your weight if overweight
  • To boil a liquid until it has decreased in amount
  • To make something smaller in size, amount, level

and

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US / ənd /

UK / ənd, ən,ænd /

A1
  • conjunction
  • Used to refer to two or more things
  • Plus; in addition; on top of that
  • Used to introduce an action that follows another

base

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US / beɪs /

UK / bes /

A2
  • noun
  • Place military personnel live, train, and operate
  • Bottom part of an object that touches a surface
  • Unit of counting, e.g. 10 for counting
  • Most important idea or ingredient to add others
  • Origin or start from which something came
  • Main place where an organization or a person works
  • verb
  • To use as the starting point or origin for
  • To have as the main location for (company, etc.)

lot

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US / lɒt /

UK / lɑt /

A1
  • noun
  • What happens to a person in life from chance; fate
  • A group of people seen together
  • Item for sale at an auction
  • Small area of land used for a purpose e.g. parking

paralyse

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US / ˈpærəlaɪz /

UK / ˈpærəˌlaɪz /

B1
  • verb
  • To be unable to move from loss of muscle function
  • To cause to be powerless and unable to function

affect

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US / ə'fekt /

UK / əˈfɛkt /

A2
  • verb
  • To cause a change in something else

only

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US / ˈəunli /

UK / ˈonli /

A1
  • adverb
  • Just one; just that amount or thing; not more than
  • Not very important or serious
  • Just that type of thing, person
  • Short time ago; not before a certain time
  • conjunction
  • Except; but

rare

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US / reə(r) /

UK / rɛr /

A2
  • adjecitve
  • (Of meat) cooked, but still red and juicy
  • Unusual or out of the ordinary; not common

release

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US / rɪ'li:s /

UK / rɪ'li:s /

A2
  • noun
  • Act of freeing someone from a duty or burden
  • Introduction of a new product, film, book, etc.
  • Relief from sadness, suffering or trouble
  • Act of freeing from a jail, cage, prison, etc.
  • verb
  • To free someone from a responsibility or burden
  • To allow a film, music etc. to be sold/distributed
  • To allow to leave a jail, cage, etc.; let out
  • To let go of something you are holding

most

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US / məʊst /

UK / most /

A1
  • adverb
  • Very; extremely
  • Greatest possible degree
  • pronoun
  • Nearly all of something

foamy

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US / ˈfəumi /

UK / ˈfomi /

B2
  • adjecitve
  • Having a mass of tiny bubbles

out

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US / aʊt /

UK / aʊt /

A1
  • adverb
  • No longer stylish (e.g. fashion)
  • Away from home, business, or the usual place
  • In a direction/movement away from inside or center
  • noun
  • Act when a batter cannot continue playing
  • verb
  • To tell people a secret

from

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US / frəm /

UK / frʌm, frɑm,frəm /

A1
  • preposition
  • Starting at a particular place, time or level

form

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US / fɔ:m /

UK / fɔrm /

A1
  • noun
  • Sports team or person's current winning record
  • Document you complete when making an application
  • Visible shape or style; type; kind
  • verb
  • To organize something such as a club or group
  • To develop; to come into a shape or substance
  • To make something into a particular shape

real

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US / rɪəl /

UK / ˈriəl, ril /

A1
  • adjecitve
  • Actually existing or happening, not imagined
  • Being important or special

mental

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US / ˈmentl /

UK / ˈmɛntl /

A2
  • adjecitve
  • Concerning the mind

depressed

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US / dɪˈprest /

UK / dɪˈprɛst /

B2
  • adjecitve
  • Feeling sad or miserable
  • verb
  • To make someone feel sad or miserable
  • To push something down

inject

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US / ɪn'dʒekt /

UK / ɪnˈdʒɛkt /

B1
  • verb
  • To add or put in more (money, energy etc.)
  • To motivate or put energy into something
  • To put medicine into someone with a syringe

help

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US / help /

UK / hɛlp /

A1
  • noun
  • Something given to enable a person to do something
  • Assistance given to someone in need
  • Someone who makes something easier or possible
  • verb
  • To act to enable a person to do something; assist
  • To make something better or less difficult

any

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US / 'enɪ /

UK / ˈɛni /

A1
  • adjecitve
  • One, or some, no matter which
  • pronoun
  • One (thing) of many; some

beast

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US / bi:st /

UK / bist /

B1
  • noun
  • Ugly or terrifying animal

treat

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US / tri:t /

UK / trit /

A1
  • noun
  • Something you buy for others as a surprise present
  • something that tastes good and that is not eaten often
  • verb
  • To pay for the food or enjoyment of someone else
  • To use medical methods to try to cure an illness
  • To act in a certain way toward someone

outside

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US / ˌaʊtˈsaɪd /

UK / aʊtˈsaɪd, ˈaʊtˌsaɪd /

A2
  • adverb
  • Beyond the limits or edges of some place, thing
  • noun
  • Area around or near something, such as a building
  • preposition
  • Beyond the limits or edges of some place, thing

make

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US / meɪk /

UK / mek /

A1
  • noun
  • Product made by a particular company; brand
  • verb
  • To arrange or prepare something e.g. dinner
  • To get to (a place) on time
  • To gain the status of (teacher, lawyer, etc.)
  • To create something by putting things together
  • To earn a certain amount of money at a job
  • To cause or force a person to do something
  • To cause something to happen or be formed

body

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US / ˈbɒd.i /

UK / ˈbɑdi /

A1
  • noun
  • An object distinct from other objects
  • A group of people involved in an activity together
  • Main part of something
  • A person's physical self

average

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US / 'ævərɪdʒ /

UK / ˈævərɪdʒ, ˈævrɪdʒ /

A2
  • adjecitve
  • Typical or normal; usual; ordinary
  • noun
  • Total of numbers divided by the number of items
  • verb
  • To add numbers then divide by the number of items

you

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US / jʊ /

UK / ju /

A1
  • pronoun
  • Person someone is speaking or writing to
  • Person or people in general

kind

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US / kaɪnd /

UK / kaɪnd /

A1
  • adjecitve
  • In a caring and helpful manner
  • friendly and considerate
  • noun
  • One type of thing

how

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US / haʊ /

UK / haʊ /

A1
  • adjecitve
  • To what degree? in what amount?
  • adverb
  • (Used to explain the way to do something)
  • exclamation
  • For what purpose or reason?
  • (Used to ask someone or something's condition)

depression

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US / dɪ'preʃn /

UK / dɪˈprɛʃən /

B2
  • noun
  • Medical condition of a lack of vitality
  • Period of unemployment and low economic activity

cosmetic

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US / kɒz'metɪk /

UK / kɑzˈmɛtɪk /

B2
  • adjecitve
  • Serving a decorative rather than a useful purpose

also

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US / 'ɔ:lsəʊ /

UK / ˈɔlso /

A1
  • adverb
  • In addition; too; in a similar way

sensitivity

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US / ˌsensə'tɪvətɪ /

UK / ˌsɛnsɪˈtɪvɪti /

A2
  • noun
  • Quality of being easily hurt emotionally

half

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US / hɑ:f /

UK / hæf, hɑf /

A1
  • adjecitve
  • Not complete
  • adverb
  • Partly; somewhat
  • noun
  • One of two equal periods of game time in a sport
  • The part you get when one is divided into two;

chemical

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US / ˈkemɪkl /

UK / ˈkɛmɪkəl /

A2
  • adjecitve
  • Made of various elements
  • noun
  • Basic substance produced by mixing elements

three

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US / θri: /

UK / θri /

A1
  • number
  • Number 3

able

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US / 'eɪbl /

UK / ˈebəl /

A2
  • adjecitve
  • Skilled; good at something
  • Having the ability to do something

open

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US / 'əʊpən /

UK / ˈopən /

A1
  • adjecitve
  • Available for use; accessible
  • Not being hidden; available for others to see
  • Being available for customers to enter or use
  • Allowing everyone to use or take part in
  • Not secret anymore
  • Not closed or shut
  • Willing to accept new ideas and thoughts
  • noun
  • Name for a tennis or golf competition
  • verb
  • To make accessible or able to be used, e.g. road
  • To start the activities or services of a business
  • To make a space or hole appear in something
  • To move or change so that it is no longer closed
  • To start something, e.g. a new business

one

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US / wʌn /

UK / wʌn /

A1
  • pronoun
  • You; we; people in general; someone
  • The thing or person previously referred to
  • adjecitve
  • Used to refer to people generally
  • Being a strong example of (something mentioned)
  • number
  • Number 1

protocol

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US / 'prəʊtəkɒl /

UK / ˈprotəˌkɔl, -ˌkol, -ˌkɑl /

B1
  • noun
  • Written agreement between countries
  • Set of rules computers use to exchange data
  • Set of rules regarding correct procedure

other

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US / 'ʌðə(r) /

UK / ˈʌðər /

A1
  • adjecitve
  • A thing different from that mentioned
  • determiner
  • (Something) else; not the first (one)
  • pronoun
  • Being the one and only thing of that category

leak

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US / li:k /

UK / lik /

B1
  • noun
  • Act of (gas, liquid) escaping through a small hole
  • Information released that wasn't supposed to be
  • verb
  • (Of a tire) to have air, liquid escaping; (Of air)
  • To make secret information public
  • (Liquid) to go out of/get in through crack/opening

into

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US / 'ɪntə /

UK / ˈɪntu /

A1
  • preposition
  • Moving or going inside something
  • In the same direction as; in the direction of
  • So as to become; taking the state of

interfere

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US / ˌɪntə'fɪə(r) /

UK / ˌɪntɚˈfɪr /

B1
  • verb
  • To get involved in something not your business

entire

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US / ɪn'taɪə(r) /

UK / ɛnˈtaɪr /

A2
  • adjecitve
  • Complete or full; with no part left out; whole

bulge

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US / bʌldʒ /

UK / bʌldʒ /

B2
  • noun
  • Rounded full or fat lump on the surface of a thing
  • Rapid increase in size
  • verb
  • To curve outward from the surface, as when full

academic

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US / ˌækə'demɪk /

UK / ˌækəˈdɛmɪk /

B1
  • adjecitve
  • Concerning education, schools, universities, etc.
  • Unimportant or irrelevant; trivial
  • noun
  • Educator teaching at a college or university
  • other
  • Concerning education, schools, universities, etc.

although

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US / ɔ:lˈðəu /

UK / ɔlˈðo /

A1
  • conjunction
  • Despite the fact that; however

this

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US / ðɪs /

UK / ðɪs /

A1
  • adjecitve
  • Used to indicate something already been discussed
  • Used to indicate something happening around now
  • adverb
  • An indication by a physical motion or gesture
  • A specific amount of
  • determiner
  • Person, thing, or idea near you
  • pronoun
  • Person, thing that has already been discussed

may

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US / meɪ /

UK / me /

A1
  • noun
  • 5th month of the year
  • other
  • Used to express a desire
  • Expresses permission, possibility or probability
  • Used to show that a thing could be true

arm

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US / ɑ:m /

UK / ɑrm /

A1
  • noun
  • Part of your body from your shoulder to your hand
  • A branch of another object e.g. company
  • The side part of a chair where your arms go
  • The influence or power an authority has
  • verb
  • To activate a weapon or bomb for use
  • To give a gun or other weapon to a person or group

the

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US / ðə /

UK / ðə /

A1
  • article
  • Used to refer to something already mentioned
  • Used to show there is only one of something
  • determiner
  • Used to describe all of a family

researcher

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US / rɪ'sɜ:tʃə(r) /

UK / rɪˈsətʃɚ /

A2
  • noun
  • Someone who works to find new facts and ideas

might

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US / maɪt /

UK / maɪt /

A1
  • other
  • Used to politely request an action
  • Used to express that something could happen
  • Power, strength, force or influence

easily

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US / ˈi:zəli /

UK / ˈizəli /

A1
  • adverb
  • Clearly; without doubt; certainly
  • Without difficulty

research

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US / rɪ'sɜ:tʃ /

UK / rɪˈsɚtʃ, ˈriˌsɚtʃ /

A2
  • noun
  • Study done to discover new ideas and facts
  • Work done to find or discover knowledge
  • verb
  • To study in order to discover new ideas and facts

good

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US / ɡʊd /

UK / ɡʊd /

A1
  • adjecitve
  • Proper, appropriate or right
  • (Of an amount) enough; plenty
  • Excellent; high quality
  • Acting well or properly; of moral character
  • In a positive or happy emotional state
  • noun
  • Advantage or benefit

give

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US / ɡɪv /

UK / ɡɪv /

A1
  • noun
  • Degree of flexibility in something, a material
  • verb
  • To hand over or present something to someone
  • To cause someone to have or experience something

but

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US / bət /

UK / bʌt,bət /

A1
  • conjunction
  • Used before you say something different, opposite

trial

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US / ˈtraɪəl /

UK / ˈtraɪəl, traɪl /

A2
  • adjecitve
  • Being made or done as a test or experiment
  • noun
  • Hearing and judgment of a case in court
  • Act or process of testing or experimenting
  • verb
  • To be made or done as a test or experiment

limitation

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US / ˌlɪmɪˈteɪʃn /

UK / ˌlɪmɪˈteʃən /

B1
  • noun
  • Act of controlling or reducing the size of

nerve

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US / nə:v /

UK / nɚv /

A2
  • noun
  • Fibers in the body that enable feeling, movement
  • Courage to do something that is difficult or risky

experience

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US / ɪk'spɪərɪəns /

UK / ɪkˈspɪriəns /

A1
  • noun
  • Thing a person has done or that happened to them
  • An event at which you learned something
  • Knowledge gained by living life, doing new things
  • verb
  • To gain knowledge by doing things

bladder

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US / ˈblædə(r) /

UK / ˈblædɚ /

B1
  • noun
  • Soft bag which holds liquid or air
  • Part of the body that holds urine

yet

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US / jet /

UK / jɛt /

A1
  • adverb
  • At a later time (used after ‘not’)
  • (Used to emphasize that thing is, will be greater)
  • Eventually; at a future time
  • Until now; up to the present
  • conjunction
  • Adding to what has been said, often as a contrast

video

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US / 'vɪdɪəʊ /

UK / ˈvɪdiˌo /

A2
  • adjecitve
  • Of a moving film, with sound
  • noun
  • Recording capturing action with sound
  • verb
  • To make a moving film of, with sound

want

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US / wɔnt /

UK / wɑnt, wɔnt /

A1
  • noun
  • Something you desire or wish for
  • State or condition of poverty
  • verb
  • To desire or wish for something; hope for a thing

neuron

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US / ˈnʊərˌɔn, ˈnjʊər- /

UK / ˈnʊrˌɑn, ˈnjʊr- /

B2
  • noun
  • A nerve cell

expect

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US / ɪk'spekt /

UK / ɪkˈspɛkt /

A1
  • verb
  • To believe something is probably going to happen

acetylcholine

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US / ˌæsɪtɪl'kɒli:n /

UK / ˌæsətɪl'koʊli:n /

A1
  • other
  • A neurotransmitter that is a derivative of choline; released at the ends of nerve fibers in the soma

would

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US / wʊd /

UK / wʊd /

A1
  • other
  • Used to indicate something imagined
  • Used to ask or request something politely
  • Verb used to indicate possibility, request etc.
  • Used to indicate a preference
  • Used to indicate a reaction
  • Indicates something that occurred repeatedly
  • Used to indicate willingness or ability to do

palm

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US / pɑ:m /

UK / pɑ:m /

B1
  • noun
  • Inner area of a person's hand
  • Tropical tree with large leaves only at its top
  • verb
  • To hide something in your hand
  • To push someone way with your hand

neurotoxin

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US / ˌnjuərəuˈtɔksin /

UK / ˈnʊroˌtɑksɪn, ˈnjʊr- /

A1
  • noun
  • Any toxin that affects neural tissues

neck

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US / nek /

UK / nɛk /

A2
  • noun
  • Part of the body joining the head and the body
  • Opening of a piece of clothing for your head
  • verb
  • (Lovers) to play affectionately; kissing

facial

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US / 'feɪʃl /

UK / ˈfeʃəl /

B2
  • adjecitve
  • Concerning or on the face
  • noun
  • Treatment to improve condition of the skin of face

tough

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US / tʌf /

UK / tʌf /

A2
  • adjecitve
  • (Of food) difficult to chew or bite through
  • Very difficult to do or deal with
  • Having strict standards
  • Being firm and not easily bent or broken
  • Being strong physically or mentally
  • Being difficult to persuade
  • Capable of violence

experimental

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US / ɪkˌsperɪˈmentl /

UK / ɪkˌspɛrəˈmɛntl /

A2
  • adjecitve
  • Using techniques that are different or untried

can

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US / kæn /

UK / kən,kæn /

A1
  • noun
  • A metal container for storing food
  • other
  • Able to; have the skill to; have the time to
  • verb
  • To have permission to
  • To be possible to do
  • To preserve food by sealing it in a metal container

botulism

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US / ˈbɒtʃəlɪzəm /

UK / ˈbɑːtʃəlɪzəm /

A1
  • noun
  • Food poisoning from ingesting botulin; not infectious; affects the CNS; can be fatal if not treated

neurologist

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US / njʊəˈrɒlədʒɪst /

UK / nʊˈrɑ:lədʒɪst /

B2
  • noun
  • Doctor specializing in the nervous system

mood

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US / mu:d /

UK / mud /

A1
  • noun
  • Emotion or a state of mind; how you feel

explanation

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US / ˌekspləˈneɪʃn /

UK / ˌɛkspləˈneʃən /

A2
  • noun
  • Details or reasons given to make something clear

fda

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US / ˌef diː ˈeɪ /

UK / ˌef diː ˈeɪ /

A1
  • abbreviation
  • FDA is an acronym

clostridium

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US / klɒs'trɪdɪəm /

UK / klɒs'trɪdɪrm /

A1
  • other
  • Spindle-shaped bacterial cell especially one swollen at the center by an endospore

become

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US / bɪ'kʌm /

UK / bɪˈkʌm /

A1
  • verb
  • To begin to be; grow to be; develop into
  • To be suitable for a particular job or role

not

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US / nɒt /

UK / nɑt /

A1
  • adverb
  • Word indicating the negative
  • (Used to form the negative of verbs)

maybe

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US / ˈmeɪbi /

UK / ˈmebi /

A1
  • adverb
  • Possibly but not certainly; perhaps

food

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US / fu:d /

UK / fud /

A1
  • noun
  • What people and animals eat to live
  • Things taken in by plants to maintain life
  • A particular style or type of cooking, e.g. Asian

development

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US / dɪ'veləpmənt /

UK / dɪˈvɛləpmənt /

A2
  • noun
  • Act or process of growing bigger or more advanced
  • A new event related to a previous event

effect

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US / ɪ'fekt /

UK / ɪˈfɛkt /

A1
  • noun
  • An advantage, benefit
  • Change brought about by a cause; result

establish

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US / ɪˈstæblɪʃ /

UK / ɪˈstæblɪʃ /

A2
  • verb
  • To set or create something to last for a long time
  • To use facts, evidence to show truth or clarity

description

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US / dɪˈskrɪpʃn /

UK / dɪˈskrɪpʃən /

A2
  • noun
  • Explanation of what something is like, looks like

mark

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US / mɑ:k /

UK / mɑrk /

A2
  • noun
  • Person's name
  • A dirty spot or line on something
  • Grade or score given for homework
  • Line or symbol made when writing
  • Particular point on a scale of measurement
  • Grade, such as a student receives in school
  • Stain or spot on something
  • Sign or symbol of a quality of feeling
  • Written sign or symbol
  • verb
  • To put a dirty spot or line on something
  • To give a grade for homework
  • To indicate something with a sign or symbol
  • To make or leave a visible sign of (path, etc.)
  • (Animals) to go to the toilet to show your area
  • To write or draw a line on something

manage

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US / ˈmænɪdʒ /

UK / ˈmænɪdʒ /

A1
  • verb
  • To survive hardships and difficulties; to cope
  • To run or operate a business by directing others

with

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US / wɪð /

UK / wɪð, wɪθ /

A1
  • preposition
  • As an employee of a certain company
  • Against something or someone
  • By using something as a means
  • Due to; because of
  • Including
  • Possessing as a feature
  • Related to
  • (Of the manner/attitude by which you do something)
  • Used to express that people or things are together

muscle

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US / 'mʌsl /

UK / ˈmʌsəl /

A2
  • noun
  • Physical power
  • Body tissue that moves parts of the body
  • verb
  • To use or muscles of force to get what you want

instance

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US / 'ɪnstəns /

UK / ˈɪnstəns /

A2
  • noun
  • An example of something; case
  • verb
  • To give as an example of something else

neurotropic

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US / ˌnjʊərəˈtrɒpɪk /

UK / ˌnjʊrəˈtrɑːpɪk /

A1
  • other
  • (Of a virus, toxin, or chemical) Tending to attack or affect the nervous system preferentially

eyelid

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US / ˈaɪlɪd /

UK / ˈaɪˌlɪd /

B2
  • noun
  • The skin that covers the eyes when you close them

dictate

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US / dɪk'teɪt /

UK / ˈdɪkˌtet /

B1
  • verb
  • To speak while someone writes down your words
  • To make a thing necessary
  • To order that something should happen

suffice

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US / səˈfaɪs /

UK / səˈfaɪs /

B2
  • verb
  • To be enough to do something

relatively

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US / ˈrelətɪvli /

UK / ˈrɛlətɪvlɪ /

A2
  • adverb
  • In a manner comparing something to something else

see

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US / si: /

UK / si /

A1
  • verb
  • To go on a date with someone
  • To predict whether something is, or will be true
  • To understand what someone says
  • To use your eyes to look at something
  • To visit a place often for sightseeing or pleasure
  • To visit or meet with someone
  • To find out by waiting or looking
  • To watch (a game, movie or TV show)

world

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US / wɜ:ld /

UK / wɜrld /

A1
  • noun
  • All the humans, events, activities on the earth
  • Political division due to some kind of similarity

properly

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US / ˈprɔpəlɪ /

UK / ˈprɑːpərli /

A2
  • adverb
  • In an appropriate or correct manner

mouth

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US / maʊθ /

UK / maʊθ /

A1
  • noun
  • Hole in the face used for eating and talking
  • Opening of a container such as a bottle
  • Area where a river enters a large body of water
  • verb
  • To say words without speaking

month

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US / mʌnθ /

UK / mʌnθ /

A1
  • noun
  • One of 12 28-31 day periods in the year

away

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US / ə'weɪ /

UK / əˈwe /

A1
  • adjecitve
  • Not present
  • adverb
  • Disappear completely
  • Doing something with a lot of energy
  • Not here; far from here; in a different direction
  • To a different area, location

blur

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US / blɜ:(r) /

UK / blɚ /

B2
  • verb
  • To make something unclear or out of focus
  • To dull the distinction between things

weakness

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US / ˈwi:knəs /

UK / ˈwiknɪs /

A2
  • noun
  • Fault or bad quality preventing success
  • Liking for something that you are a bit ashamed of

know

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US / nəʊ /

UK / noʊ /

A1
  • verb
  • To be familiar with a person or place, thing
  • To feel sure or be convinced about something
  • To discover or be aware of something
  • To be able to distinguish
  • To have knowledge of things

could

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US / kəd /

UK / kʊd /

A1
  • other
  • Past form of 'can' to mean have ability
  • Used to ask for something politely, or to offer

behind

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US / bɪˈhaɪnd /

UK / bɪˈhaɪnd /

A1
  • adjecitve
  • Concerning a later or slower time than expected
  • Being in a losing position in a sporting event
  • Being in the past; old fashioned
  • adverb
  • Remaining
  • noun
  • The part of the body that one sits on
  • preposition
  • At or toward the back of someone or something
  • Supporting or helping someone

next

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US / nekst /

UK / nɛkst /

A1
  • adverb
  • The one that follows another in time or order
  • At a time or place directly after the present one
  • noun
  • The one that follows after
  • adjecitve
  • Immediately after the previous one
  • First occurrence after the present one

hand

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US / hænd /

UK / hænd /

A1
  • noun
  • Cards given to a player in a card game
  • Piece of a clock that points to the time
  • Someone who performs physical tasks or work
  • Body part at the end of a person's arm
  • Help for someone performing a particular action
  • Condition of having power or influence
  • Member of the crew of a ship
  • verb
  • To give something to someone personally

clear

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US / klɪə(r) /

UK / klɪr /

A1
  • adjecitve
  • Empty; without anything in it or on it
  • Being certain and without doubt
  • Being without any streaks, spots, or cracks
  • Easy to understand; well-explained; obvious
  • adverb
  • Completely; entirely; through the whole of
  • Away from; free from
  • verb
  • To recover from or remove a problem
  • To get rid of the entire contents of
  • To give permission for something to happen
  • To make a place or surface empty by removing
  • To prove that someone is not guilty or to blame

without

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US / wɪˈðaʊt /

UK / wɪðˈaʊt, wɪθ- /

A1
  • preposition
  • Not with; not having

substance

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US / 'sʌbstəns /

UK / ˈsʌbstəns /

A2
  • noun
  • Essence of; most basic or central qualities
  • Particular type of material
  • Having material form; existing
  • Quality of truth, importance, or meaningfulness

overactive

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US / ˌəʊvər'æktɪv /

UK / ˌoʊvər'æktɪv /

C2
  • adjecitve
  • More active than normal, other people

last

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US / lɑ:st /

UK / læst /

A1
  • adjecitve
  • Most recent; the latest
  • The one before
  • adverb
  • Final; with nothing following; after all others
  • Most recent; the latest
  • determiner
  • The one at the end
  • verb
  • To remain or continue for a certain period of time

cover

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US / 'kʌvə(r) /

UK / ˈkʌvɚ /

A1
  • noun
  • A different version of another song
  • Bed sheets; blankets
  • (Police or military) protection from attack
  • Amount of money to be paid in an insurance claim
  • Thing you put over something to close or hide it
  • Front and back part of a book or magazine
  • Shelter built to protect from the natural elements
  • verb
  • To record a different version of another song
  • To include as part of its area
  • To put something over something to hide it
  • To discuss a subject in a talk or meeting
  • To form a layer over something so it is hidden
  • To have sufficient funds to pay for something
  • To include something within an agreed limit
  • To report news on TV, radio or in a newspaper
  • (Police or military) to protect from attack
  • To travel a certain distance in a given time
  • To wrap something with something, such as a cloth

have

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US / həv /

UK / hæv /

A1
  • verb
  • To drink, smoke, eat or use something
  • To experience the effects of something
  • To organize an event, or join in an activity
  • To own, possess, or hold something
  • To cause to happen or produce a particular effect

botox

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US / ˈbəʊtɒks /

UK / ˈboʊtɑːks /

A1
  • noun

almost

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US / 'ɔ:lməʊst /

UK / ˈɔlˌmost, ɔlˈmost /

A1
  • adverb
  • Only a little less than, nearly, not quite

tired

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US / ˈtaɪəd /

UK / ˈtaɪərd /

B1
  • adjecitve
  • Without energy so you want to rest or fall asleep
  • verb
  • To lose, cause to lose energy so you want to rest

notice

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US / 'nəʊtɪs /

UK / ˈnotɪs /

A1
  • noun
  • Time by when you must leave, e.g. if you are fired
  • Paper with an announcement, e.g. pinned to a board
  • verb
  • To become aware by sight, touch, or hearing

increase

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US / ɪn'kri:s /

UK / ɪnˈkris /

A1
  • noun
  • Fact of increasing; amount something grows by
  • verb
  • To make or become larger in size or amount

emotion

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US / iˈməuʃən /

UK / ɪˈmoʃən /

A2
  • noun
  • A feeling such as sadness, anger or love

probably

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US / ˈprɒbəbli /

UK / ˈprɑbəbli /

A1
  • adverb
  • That is likely to happen or be true

million

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US / ˈmɪljən /

UK / ˈmɪljən /

A1
  • number
  • 1,000,000

third

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US / θɜ:d /

UK / θɜ:rd /

A1
  • adjecitve
  • 3rd: Number after second

develop

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US / dɪ'veləp /

UK / dɪˈvɛləp /

A1
  • verb
  • To explain something in steps and in detail
  • To create or think of something
  • To grow bigger, more complex, or more advanced
  • To make a photograph from film

consult

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US / kənˈsʌlt /

UK / kənˈsʌlt /

A2
  • verb
  • To ask the advice, opinion of a (paid) specialist
  • To discuss something to make a decision
  • To look at a book or map for information

certain

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US / ˈsə:tn /

UK / ˈsɚtn /

A1
  • adjecitve
  • Definite, fixed
  • Referring to an unspecified amount or quantity
  • Being sure about something; without doubt

wrinkle

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US / 'rɪŋkl /

UK / ˈrɪŋkəl /

B2
  • noun
  • Small folds in the skin, e.g. as a sign of age

will

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US / wɪl /

UK / wɪl /

A1
  • noun
  • Desire or choice of someone
  • Document saying who gets your money when you die
  • Strong desire to do something; determination
  • Desire to do something; strong wish to do
  • other
  • Used with verbs to express the future
  • verb
  • To leave property to someone after your death
  • To use mental effort to make something happen
  • Am (is, are) likely to do
  • To influence someone to do something
  • To make something happen by strongly wanting it

many

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US / 'menɪ /

UK / ˈmɛni /

A1
  • determiner
  • Used to refer a large number of things

use

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US / ju:s /

UK / ju:s /

A1
  • noun
  • Ability to employ something
  • Need to enable it to work
  • Permission to do something with something
  • Act of spending money
  • Operation of a machine for its function
  • verb
  • To have; to eat, drink, consume etc.
  • To need to operate or work
  • To operate a machine, e.g. a computer
  • To treat a person badly
  • To do something with, for a task or purpose

speak

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US / spi:k /

UK / spik /

A1
  • verb
  • To be able to use a certain language
  • To use words to tell information, express thoughts

someone

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US / ˈsʌmwʌn /

UK / ˈsʌmˌwʌn, -wən /

A1
  • pronoun
  • Person who is not known or named

taste

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US / teɪst /

UK / test /

A2
  • noun
  • (Good) sense of style in clothes, art, or manners
  • Flavor in your mouth from food or drink
  • A liking for something; preference
  • Brief experience of something
  • verb
  • To experience something
  • To experience the flavor of food, drink
  • To briefly experience to see if you like something

mild

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US / maɪld /

UK / maɪld /

A2
  • adjecitve
  • Gentle in nature or behavior
  • Being neither too cold nor too hot

consider

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US / kən'sɪdə(r) /

UK / kənˈsɪdər /

A1
  • verb
  • To think carefully about something

sweat

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US / swet /

UK / swɛt /

A2
  • noun
  • An amount of hard work
  • (Of work, job) hard; needing effort
  • Liquid from your skin when you are hot or nervous
  • verb
  • To do an amount of hard work
  • To be worried or anxious about something
  • To produce drops of water from your skin when hot

temporary

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US / ˈtemprəri /

UK / 'tempəreri /

A2
  • adjecitve
  • Continuing for a limited time; not permanent

sometime

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US / ˈsʌmtaɪm /

UK / ˈsʌmˌtaɪm /

A1
  • adjecitve
  • At an unknown time in the future

should

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US / ʃʊd /

UK / ʃʊd /

A1
  • other
  • Used to indicate what is proper or reasonable

respond

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US / rɪ'spɒnd /

UK / rɪˈspɑnd /

A2
  • verb
  • To answer something or someone
  • To have a good reaction to e.g. medical treatment

medical

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US / ˈmedɪkl /

UK / ˈmɛdɪkəl /

A2
  • adjecitve
  • Of or relating to physical health or medicine
  • noun
  • A health check or test

bacterium

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US / bæk'tɪərɪəm /

UK / bækˈtɪriəm /

B2
  • noun
  • The very small creatures that can cause disease

try

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US / traɪ /

UK / traɪ /

A1
  • noun
  • Act of putting the ball over the rugby goal line
  • verb
  • To make an effort, to attempt to do something
  • To examine someone or something in a court of law
  • To test to see if it is good or you like it
  • To make a person go through hardship; test
  • To examine something to see if it works

small

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US / smɔ:l /

UK / smɔl /

A1
  • adjecitve
  • Little in size; not big
  • (Of letters) not written in capital letters
  • Being insignificant or minor
  • (Of a business) with few people or things; local
  • (Of voice) being soft and quiet
  • (Of a child) being young

new

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US / nju: /

UK / nu, nju /

A1
  • adjecitve
  • Not old, recently born, built or made
  • Being or doing something for the first time
  • Not felt, seen or known previously
  • Having been recently bought or obtained

extreme

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US / ɪk'stri:m /

UK / ɪkˈstrim /

B1
  • adjecitve
  • Very great in degree
  • Farthest from a center
  • Very severe; very strong
  • noun
  • Effort that is thought more than is necessary

procedure

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US / prəˈsi:dʒə(r) /

UK / prəˈsidʒɚ /

B1
  • noun
  • A medical operation
  • Usual or standard steps taken to do something

feel

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US / fi:l /

UK / fil /

A1
  • verb
  • To be aware of or experience an emotion, sensation
  • To sense through direct contact; touch

area

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US / 'eərɪə /

UK / ˈɛriə /

A1
  • noun
  • Amount of measured space
  • A specific section or space; part of a region
  • A subject or field of study

happen

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US / 'hæpən /

UK / ˈhæpən /

A1
  • verb
  • To take place or occur

each

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US / i:tʃ /

UK / itʃ /

A1
  • determiner
  • Every one of two or more things
  • pronoun
  • Per one person or thing

cell

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US / sel /

UK / sɛl /

A2
  • noun
  • Smallest unit of living things in biology
  • Group of people - often from a secret organization
  • Prisoner's room in a jail
  • Shortened form of 'cellphone'

similar

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US / ˈsɪmələ(r) /

UK / ˈsɪməlɚ /

A1
  • adjecitve
  • Nearly the same; alike

tell

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US / tel /

UK / tɛl /

A1
  • verb
  • To (strongly) advise a person to do something
  • To be able to guess
  • To say or communicate information to someone
  • To inform, but without speaking; indicate
  • To have a negative effect on someone
  • To order someone to do something; command
  • To recognize something based on certain signs
  • To report something to an authority
  • To explain something or teach someone something

smile

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US / smaɪl /

UK / smaɪl /

A1
  • noun
  • Raising the corners of the mouth showing happiness
  • verb
  • To put up the corners of mouth to show happiness

education

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US / ˌedʒuˈkeɪʃn /

UK / ˌɛdʒəˈkeʃən /

A2
  • noun
  • Academic field studying the practice of teaching
  • Process of giving or receiving teaching

disrupt

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US / dɪsˈrʌpt /

UK / dɪsˈrʌpt /

B2
  • verb
  • To cause a disturbance in an activity in progress

watch

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US / wɒtʃ /

UK / wɑtʃ /

A1
  • noun
  • Period of time someone is responsible for guarding
  • Device you wear on your wrist that shows the time
  • Official warning statement, e.g. of bad weather
  • verb
  • To keep in check, manage, or control something
  • To look at something for entertainment, e.g. TV
  • To guard a place or people; protect child, etc.
  • To look at carefully to work out what is happening
  • To protect and care for someone or something

mean

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US / mi:n /

UK / min /

A1
  • adjecitve
  • Being good at
  • Nasty; unkind
  • Not liking to spend money; cheap; stingy
  • noun
  • Average of a set of numbers
  • verb
  • To express a particular idea or thought
  • To intend to do something in particular
  • To have a particular meaning or value

dial

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US / 'daɪəl /

UK / ˈdaɪəl /

B1
  • noun
  • Face of a clock that shows the time
  • A knob or switch
  • verb
  • To call a person or place on a telephone

enough

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US / ɪˈnʌf /

UK / ɪˈnʌf /

A1
  • adjecitve
  • Sufficient to answer the need
  • adverb
  • To a satisfactory degree
  • pronoun
  • Equal to what is needed; as much as required
  • Adequate number or amount

case

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US / keɪs /

UK / kes /

A1
  • noun
  • Container used to carry things, e.g. clothes
  • Set of facts about a crime
  • Set of facts about an event
  • Example or instance of something
  • verb
  • To find out about a place, as in planning to steal

sensory

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US / ˈsensəri /

UK / ˈsɛnsəri /

B2
  • adjecitve
  • Referring to the physical senses

right

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US / raɪt /

UK / raɪt /

A1
  • adjecitve
  • Correct or true
  • The south side of you looking at the rising sun
  • adverb
  • Exactly in a place or time
  • Being appropriate for a particular event
  • In a straight or direct manner
  • noun
  • Something you are legally or morally allowed to do
  • Ideal of what is just and good
  • Political view based on conservatism
  • verb
  • To fix something previously wrong or unjust
  • To make upright, as a boat that has turned over

despite

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US / dɪˈspaɪt /

UK / dɪˈspaɪt /

A2
  • preposition
  • Without being affected by something; in spite of

essentially

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US / ɪˈsenʃəli /

UK / ɪˈsenʃəli /

A2
  • adverb
  • Basically; (said when stating the basic facts)

what

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US / wɒt /

UK / hwɑt, hwʌt, wɔt, wʌt,hwət, wət /

A1
  • pronoun
  • Thing or things that; the same kind as
  • Used to emphasize something you are about to say
  • adjecitve
  • Used to refer to a particular amount, or number
  • Used to place emphasis on a particular quality
  • adverb
  • To a certain degree
  • determiner
  • Question words used for asking for information
  • exclamation
  • Used to express excitement, shock, or surprise
  • Used to ask people to repeat something they said

that

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US / ðæt /

UK / ðæt, ðət /

A1
  • adjecitve
  • The person or thing being talked about
  • Used to identify something both the speakers know
  • adverb
  • Used to reinforce adjectives and adverbs
  • To such a degree
  • conjunction
  • Used to connect a noun clause
  • Used to introduce an adverbial clause
  • Used to introduce a noun clause
  • determiner
  • Used as a noun to refer to something
  • pronoun
  • Referring an object far away
  • Used to refer to the relative pronoun ‘which’

week

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US / wi:k /

UK / wik /

A1
  • noun
  • Period of seven days from Sunday to Saturday

like

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US / laɪk /

UK / laɪk /

A1
  • adjecitve
  • Being equal in status or kind to something else
  • Similar; the same
  • adverb
  • For example
  • preposition
  • Used as a filler; used to ad emphasis
  • In a way similar to the way something is done
  • Such as; for example
  • verb
  • To want to
  • To find something pleasing; to prefer something

site

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US / saɪt /

UK / saɪt /

A2
  • noun
  • Place that is reserved for a particular activity
  • Location of building work
  • Location of something
  • Place where something of special interest happened
  • Website
  • verb
  • To place something in a particular position, area

people

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US / 'pi:pl /

UK / ˈpipəl /

A1
  • noun
  • Persons sharing culture, country, background, etc.
  • Men, Women, Children

health

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US / helθ /

UK / hɛlθ /

A1
  • noun
  • (Person, company) being in a good condition; well

eye

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US / aɪ /

UK / aɪ /

A1
  • noun
  • The part of the body that you see with
  • The skill to see the good and bad parts of a thing
  • Hole at the end of a needle
  • verb
  • To watch or study something closely

even

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US / 'i:vn /

UK / ˈivən /

A1
  • adjecitve
  • Being equal in influence, power, possibility etc.
  • Being divided equally or fairly
  • (Of teams/contest) with similar chances of success
  • Smooth, level, or regular
  • Can be divided by 2; ending in 2, 4, 6, 8, or 0
  • At a regular, equally steady manner
  • Remaining steady and unchanging
  • adverb
  • (When this is surprising) as well; too
  • (Used to compare two things/stress the difference)
  • verb
  • To make something level; to flatten
  • To make something equal

care

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US / keə(r) /

UK / kɛr /

A1
  • noun
  • Treatment you receive for your health or safety
  • Something that a person worries about
  • verb
  • To feel interest, concern, or worry
  • To look after someone or something

about

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US / ə'baʊt /

UK / əˈbaʊt /

A1
  • adverb
  • To be ready to; going to
  • Nearly; approximately; roughly
  • Near; next to; close to
  • In every direction; in the area of
  • preposition
  • Concerning or of (a topic)

vision

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US / 'vɪʒn /

UK / ˈvɪʒən /

A2
  • noun
  • Ability to see; eyesight
  • Something you see in your imagination or dreams
  • Ability to plan for the future of something

purify

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US / ˈpjʊərɪfaɪ /

UK / ˈpjʊrɪfaɪ /

B2
  • verb
  • To make pure by removing unwanted substances
  • To make someone feel pure by removing guilt

include

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US / ɪnˈklu:d /

UK / ɪnˈklud /

A1
  • verb
  • To make someone, something part of a group

contaminate

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US / kənˈtæmɪneɪt /

UK / kənˈtæməˌnet /

B2
  • verb
  • To make impure by adding a harmful element

block

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US / blɒk /

UK / blɑk /

A2
  • noun
  • Solid piece of material used for building
  • A piece of wood, chocolate etc.
  • Hard piece of wood, stone etc. with straight edges
  • Building made up of offices or apartments
  • Area of a city divided by four streets
  • verb
  • To stop from going forward or making progress

traction

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US / ˈtrækʃn /

UK / ˈtrækʃən /

C1
  • noun
  • Force causing moving thing to stick, e.g. on roads

scalp

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US / skælp /

UK / skælp /

B2
  • noun
  • Part of the human head covered by hair
  • verb
  • To sell e.g. tickets far above the original price

get

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US / ɡet /

UK / ɡɛt /

A1
  • verb
  • To become affected by illness or disease
  • To begin to feel or understand an emotion or idea
  • To send or bring someone or something home, etc.
  • To go somewhere to obtain something
  • To (cause to) do a particular thing
  • To obtain, receive or be given something
  • To currently have
  • To prepare for use
  • To understand something being said or read

action

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US / 'ækʃn /

UK / ˈækʃən /

A2
  • noun
  • Something that a person or thing does
  • verb
  • To act to do something

tracy

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US / ˈtreisi /

UK / ˈtresi /

A1
  • proper noun
  • A commercial and industrial city in north central California, in the San Joaquin Valley; population

take

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US / teɪk /

UK / tek /

A1
  • noun
  • Filming of a single scene for TV or the movies
  • verb
  • To accept something that is offered
  • To use a method of traveling, e.g. a bus or train
  • To use a camera to make (a photo)
  • To pick up something and go away with it
  • To study a subject in school
  • To attempt to pass (an exam)
  • To require a certain amount of time, money, space

crucial

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US / 'kru:ʃl /

UK / ˈkruʃəl /

B1
  • adjecitve
  • Extremely important or necessary

article

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US / 'ɑ:tɪkl /

UK / ˈɑrtɪkəl /

A2
  • noun
  • Word such as 'a', 'an', or 'the' used before nouns
  • Piece of writing about a particular subject
  • Piece of something, e.g. clothing
  • Section of a business contract or law

their

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US / ðɛː /

UK / ðer /

A1
  • determiner
  • Belonging to them

way

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US / weɪ /

UK / we /

A1
  • adverb
  • Used to emphasize the amount of something
  • noun
  • Particular aspect of something being thought about
  • One of various choices that could be made
  • Particular existing condition or state
  • (Often long) distance or length of time
  • How something is done
  • Route to go to a place
  • Small street
  • Usual behavior, emotions or habits of someone

symptom

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US / 'sɪmptəm /

UK / ˈsɪmtəm, ˈsɪmp- /

B1
  • noun
  • Sign that suggests that there is a problem

technique

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US / tekˈni:k /

UK / tɛkˈnik /

A2
  • noun
  • Way of doing by using special knowledge or skill

move

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US / mu:v /

UK / muv /

A1
  • noun
  • Act of moving a playing piece in chess, etc.
  • An action; doing something
  • Step taken to achieve a goal
  • verb
  • To cause someone to have certain emotions
  • To cause something to change to a different place
  • To change where people live or a business operates
  • To take action to do or achieve something

several

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US / ˈsevrəl /

UK / ˈsɛvərəl,ˈsɛvrəl /

A1
  • adjecitve
  • Many of
  • pronoun
  • More than two but not a large amount

expression

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US / ɪk'spreʃn /

UK / ɪkˈsprɛʃən /

A2
  • noun
  • Act of making your thoughts and feelings known
  • Group of words that have a specific meaning

evidence

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US / 'evɪdəns /

UK / ˈɛvɪdəns /

A1
  • noun
  • Factual proof that helps to establish the truth

communication

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US / kəˌmju:nɪ'keɪʃn /

UK / kəˌmjunɪˈkeʃən /

A2
  • noun
  • Talking to people; giving information to people

thank

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US / θæŋk /

UK / θæŋk /

A1
  • verb
  • To tell someone you are grateful to them

pay

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US / peɪ /

UK / pe /

A1
  • noun
  • Money you receive from your job, work, etc.
  • verb
  • To give money for goods or work done
  • To give (attention, respect, etc.) to
  • To be punished or suffer for something you did
  • To make (a visit) to a person or place

look

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US / lʊk /

UK / lʊk /

A1
  • noun
  • Person's beauty or physical attractiveness
  • Particular style of dress, clothes, or appearance
  • The way someone, something appears to be
  • Act of searching for or examining something
  • verb
  • To appear to be; seem

approve

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US / əˈpru:v /

UK / əˈpruv /

A2
  • verb
  • To formally accept something or grant permission
  • To have a positive opinion of someone or something

theory

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US / ˈθiəri /

UK / ˈθiəri, ˈθɪri /

A2
  • noun
  • Ideas or principles that explain facts or events

show

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US / ʃəʊ /

UK / ʃo /

A1
  • noun
  • False display of love, emotion or action
  • An event for displaying or promoting goods
  • Play, opera or theater production
  • Presentation that is broadcast on TV or radio
  • verb
  • To be easily seen or displayed
  • To display your emotions or feelings
  • To let someone see something; display
  • To explain or teach how something is done
  • To lead someone somewhere; point them to something
  • To prove something to be true, correct
  • To reveal or allow something to be seen

result

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US / rɪ'zʌlt /

UK / rɪˈzʌlt /

A2
  • noun
  • Something produced through tests or experiments
  • Final score of a competition, election or game
  • verb
  • To be the outcome of other causes and effects

medicine

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US / ˈmedsn /

UK / ˈmɛdɪsɪn /

A2
  • noun
  • Something used in treating illness or pain
  • Science of preventing, treating, or curing disease

both

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US / bəuθ /

UK / boθ /

A1
  • determiner
  • Used to refer to two things at the same time
  • pronoun
  • Used to refer to two things at the same time

change

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US / tʃeɪndʒ /

UK / tʃendʒ /

A1
  • noun
  • Exchange of one set of clothes for another
  • Money in the form of coins instead of paper
  • Money returned after giving too much
  • Act of making or becoming something else
  • verb
  • To exchange one set of clothes for another
  • To exchange one kind of money for another
  • To replace something with another thing
  • To make or become something else
  • To go from one train, bus, etc. and go to another

they

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US / ðeɪ /

UK / ðe /

A1
  • pronoun
  • Two or more people, animals, or things

toxin

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US / ˈtɒksɪn /

UK / ˈtɑ:ksɪn /

B1
  • noun
  • Any poisonous substance

shoulder

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US / ˈʃəʊldə(r) /

UK / ˈʃoldɚ /

A2
  • noun
  • Part of the body where an arm attaches or joins
  • Meat that comes from an animal's upper front leg
  • Part of a shirt or coat that covers the shoulders
  • verb
  • To carry something around your neck
  • To push something using the top part of your arm
  • To accept a job or responsibility

reference

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US / 'refrəns /

UK / ˈrɛfərəns, ˈrɛfrəns /

A2
  • noun
  • A letter of recommendation, e.g. for a job
  • Note in a book, etc. giving source of information
  • A location on a map
  • verb
  • To cite a piece of research in speech or writing

medication

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US / ˌmedɪˈkeɪʃn /

UK / ˌmɛdɪˈkeʃən /

B2
  • noun
  • Substance to relieve pain or cure sickness

error

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US / ˈerə(r) /

UK / ˈɛrɚ /

A2
  • noun
  • Something that is not correct; a mistake

everything

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US / 'evrɪθɪŋ /

UK / ˈɛvriˌθɪŋ /

A1
  • pronoun
  • All of the things mentioned

feedback

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US / ˈfi:dbæk /

UK / ˈfidˌbæk /

B1
  • noun
  • A response or opinion, about a service, etc.

botulinum

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US / ˌbɒtjʊˈlaɪnəm /

UK / ˌbɑːtʃəˈlɑɪnəm /

A1
  • noun

between

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US / bɪˈtwi:n /

UK / bɪˈtwin /

A1
  • preposition
  • From one person, thing, or place, to another
  • In the space that separates two objects
  • Among two or more people who share something

work

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US / wɜ:k /

UK / wɚk /

A1
  • adjecitve
  • Activity completed in order to make money
  • noun
  • The product of some artistic or literary endeavor
  • Everything created by an author, artist, musician
  • Activity you do in order to make money
  • Place of employment
  • Final product or result of a some labor or effort
  • verb
  • To bring into a specific state of success
  • To be functioning properly, e.g. a car
  • To do your job in your company or workplace
  • To make an effort to do something
  • To operate a machine or device

throw

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US / θrəʊ /

UK / θroʊ /

A1
  • noun
  • Arm movement to make a thing fly through the air
  • Loose cloth or blanket (usually over a chair)
  • Forcibly putting someone on the ground
  • verb
  • To use your arm to make something fly in the air
  • To move part of your body suddenly and forcefully
  • To confuse or upset someone
  • (E.g. judo) to forcibly put someone on the ground
  • To put something somewhere suddenly and roughly

gain

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US / ɡeɪn /

UK / ɡen /

A2
  • noun
  • An increase in something, such as weight
  • verb
  • To increase in something, such as weight
  • To get something wanted, needed or valued

who

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US / hu: /

UK / hu /

A1
  • pronoun
  • Which person
  • Used to introduce information about people

top

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US / tɒp /

UK / tɑp /

A1
  • adjecitve
  • Being good or great; excellent
  • Being the most in degree or quality
  • noun
  • Item of clothing covering shoulders to waist, hips
  • A cover or lid
  • Part (e.g. road) that is the furthest away
  • Highest or upper part or point of something
  • Best or highest status or position
  • Flat upper surface or edge of an object
  • Child's toy that spins on its point
  • Upper section or leaves of fruits and vegetables
  • Winning in a sport or contest
  • verb
  • To be higher or larger than a specific value
  • To arrive at the highest point of something
  • To put a cover or layer or over something
  • To kill; murder
  • To hold the highest position on a list
  • To be more important, successful or better than
  • To beat someone or win at a game

produce

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US / prə'dju:s /

UK / prəˈdus, -ˈdjus, pro- /

A1
  • noun
  • Fresh foods such as fruits and vegetables
  • verb
  • To grow something naturally
  • To make something appear
  • To manufacture something using machines
  • To control the making a movie or television show

though

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US / ðəu /

UK / ðo /

A1
  • adverb
  • Although, despite the fact that

promise

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US / 'prɒmɪs /

UK / ˈprɑmɪs /

A1
  • verb
  • To say you will certainly do something

poisoning

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US / ˈpɔɪəznɪŋ , ˈpɔɪzənɪŋ /

UK / ˈpɔɪzənɪŋ /

A2
  • verb
  • To affect something in a very negative way
  • To hurt or kill with a dangerous substance

hour

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US / 'aʊə(r) /

UK / aʊr /

A1
  • noun
  • 60 minutes
  • Particular time of the day
  • Fixed, regularly occurring time

under

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US / ˈʌndə(r) /

UK / ˈʌndɚ /

A1
  • adjecitve
  • In the same place as another thing, but lower
  • adverb
  • In a lower quantity or price than expected
  • preposition
  • According to the terms of an agreement or law
  • Managed or controlled by the authority of
  • Being of a lesser quality or amount than expected
  • Influenced or affected by something or someone
  • Less or lower in age, amount, size or number

standard

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US / 'stændəd /

UK / ˈstændəd /

A2
  • adjecitve
  • Being the accepted normal level of quality
  • (Of a language) being the most accepted in a place
  • noun
  • Official unit of measuring something
  • Principle of behaving in a moral way

strong

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US / strɒŋ /

UK / strɔŋ /

A1
  • adjecitve
  • (Of tea or beer) dark or thick
  • Having big muscles; physically powerful

positive

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US / ˈpɒzətɪv /

UK / ˈpɑzɪtɪv /

A2
  • adjecitve
  • Showing agreement or support for something
  • Being sure about something; knowing the truth
  • Having the charge produced by electrons
  • Being good or useful
  • Showing that a chemical is present in a test

few

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US / fju: /

UK / fju /

A1
  • pronoun
  • Not many, a small number

bubble

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US / ˈbʌbl /

UK / ˈbʌbəl /

B1
  • noun
  • A small ball of air inside of a liquid
  • verb
  • (Of a liquid) to produce bubbles, as when boiling
  • To show intense emotion, e.g. excitement, anger

difficult

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US / 'dɪfɪkəlt /

UK / ˈdɪfɪˌkʌlt, -kəlt /

A1
  • adjecitve
  • Hard; not easy; you need to work hard to do it

breathing

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US / ˈbri:ðɪŋ /

UK / ˈbriðɪŋ /

A2
  • verb
  • To move air into and out of your lungs
  • To say something very softly
  • To stop moving so one can rest

consume

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US / kən'sju:m /

UK / kənˈsum /

A2
  • verb
  • To eat, drink, buy or use up something
  • To take all your energy; focus the attention

send

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US / send /

UK / sɛnd /

A1
  • verb
  • To cause to behave or respond in a particular way
  • To cause mail or packages to go to another place
  • To move something quickly in a particular way
  • To give information or greetings to someone

distress

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US / dɪ'stres /

UK / dɪˈstrɛs /

B1
  • noun
  • State of great sadness, anxiety or pain
  • Condition of danger or emergency
  • State of lacking money and basic needs
  • Condition of physical illness, pain or suffering
  • verb
  • To cause someone anxiety or sadness
  • To be in financial trouble

amount

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US / ə'maʊnt /

UK / əˈmaʊnt /

A1
  • noun
  • Quantity of something
  • verb
  • To add up to a certain figure

talk

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US / tɔ:k /

UK / tɔk /

A1
  • noun
  • Style of speaking
  • Discussion between two countries
  • Giving information in front of people; lecture
  • Saying things or ideas to someone with words
  • verb
  • To make a formal speech about something
  • To say things or ideas to someone with words

regeneration

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US / rɪˌdʒenə'reɪʃn /

UK / rɪˌdʒɛnəˈreʃən /

B2
  • noun
  • Act of adding more life or energy into

insurance

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US / ɪnˈʃʊərəns /

UK / ɪnˈʃʊrəns /

A2
  • noun
  • Protection against loss/injury/death you pay for

therapy

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US / 'θerəpɪ /

UK / ˈθɛrəpi /

B2
  • noun
  • Treatment to help cure an illness

tolerate

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US / ˈtɒləreɪt /

UK / ˈtɑ:ləreɪt /

B1
  • verb
  • To be able to adjust to changes of various kinds
  • To be able to survive under specific conditions
  • To let people do, say or believe what they wish
  • To be able to drink (e.g. alcohol) without effects

time

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US / taɪm /

UK / taɪm /

A1
  • noun
  • Speed at which music is played; tempo
  • Point as shown on a clock, e.g. 3 p.m
  • Number of hours, minutes needed to do something
  • Occasion when something happens
  • Period or occasion that something occurred
  • Period in history or the past
  • Something measured in minutes, hours, days, etc.
  • How long an event takes; duration
  • verb
  • To check speed at which music is performed
  • To choose a specific moment to do something
  • To measure how long an event takes, e.g. a race
  • To schedule something to occur at a specific moment

for

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US / fə(r) /

UK / fɔr,fə /

A1
  • preposition
  • Used to show the purpose, or need of something

communicate

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US / kə'mju:nɪkeɪt /

UK / kəˈmjunɪˌket /

A2
  • verb
  • To give and exchange information

within

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US / wɪˈðɪn /

UK / wɪðˈɪn, wɪθ- /

A1
  • adverb
  • Inside the limits of an area, time or range
  • preposition
  • From the inside of something

since

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US / sɪns /

UK / sɪns /

A1
  • adverb
  • At a point before the present time
  • conjunction
  • For this reason; because
  • preposition
  • From the time in the past that

dent

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US / dent /

UK / dɛnt /

B2
  • noun
  • Place on a car, etc. where it has been pushed in
  • verb
  • To make a depression on a (metal) surface

relax

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US / rɪˈlæks /

UK / rɪˈlæks /

A1
  • verb
  • To calm or quiet yourself, or stop worrying
  • To release the tightness in muscles
  • To make a rule or law less strict

specialist

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US / 'speʃəlɪst /

UK / ˈspɛʃəlɪst /

B1
  • noun
  • Person who works in one specific area or field

improvement

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US / ɪmˈpru:vmənt /

UK / ɪmˈpruvmənt /

A2
  • noun
  • Addition or change that makes something better
  • Subtitles section
  • Depression is a tough beast.
  • It affects millions of people.
  • We've developed lots of medication treatments and even therapy treatment.
  • But despite this, about a third of people don't respond to these treatments and remain depressed.
  • Today, I'm going to tell you about a relatively new development that's gaining some traction, and that is Botox injections.
  • I'm Dr. Tracey Marks, a psychiatrist, and I make mental health education videos.
  • Botox, or botulinum toxin, is a neurotoxin produced by the bacterium Clostridium botulinum.
  • A neurotoxin is a substance that interferes with the functions of the nerve cells.
  • One of the ways it does this is by disrupting or blocking the communication between neurons.
  • If neurons can't communicate with each other, they don't function properly.
  • Botulinum toxin blocks the nerve cells from releasing acetylcholine, and this action paralyzes the muscles so that it can't move.
  • You're probably familiar with Botox being used for cosmetic procedures to reduce facial wrinkles in the forehead and around the eyes and mouth.
  • It's also used to treat migraine headaches.
  • When it's used for migraines, you get injections in the forehead, scalp, neck, and shoulders.
  • These treatments aren't new.
  • Botox has been used for facial wrinkles since 2002, and for migraines since 2010.
  • The paralyzing effects of these medications are temporary, lasting on average about three months.
  • As time has progressed, there have been other conditions that Botox has helped, like overactive bladder and extreme sweating under your arms and the palms of your hands.
  • As more people have used it, we've seen that many people also have had improvement in their depression symptoms.
  • The theory behind this potential treatment is based on the facial feedback hypothesis.
  • I talked about this in a video I did using the half smile technique to manage difficult emotions.
  • Essentially, the idea is that facial expressions can affect your mood when your facial muscles send positive sensory feedback to your brain that changes your emotional experience.
  • So in this case with Botox, relaxing your facial muscles with the toxin sends positive feedback in a way that improves your depression symptoms.
  • That's one theory, but it's not the entire explanation.
  • Some researchers have seen that the toxin increases serotonin and brain-derived neurotropic factor, which is a chemical that increases nerve regeneration.
  • I have some article references in the description if you wanna read more about it.
  • But suffice it to say that there is strong enough evidence to show that injecting botulinum toxin into the muscles of the forehead and around the eyes has antidepressant effects.
  • So how does this work in the real world outside of academic medicine and research?
  • Although botulinum toxin is FDA approved for certain medical conditions, it's not approved for depression treatment yet.
  • That means you'll have to see a specialist who keeps up with the research to do it and your insurance may not pay for it.
  • The doctors who typically give these kinds of injections are neurologists, dermatologists, and plastic surgeons.
  • So far, it looks like it takes several weeks to see results similar to the antidepressants, and it's not clear how long the improvement lasts.
  • So we don't have an established protocol on how many injections you should get.
  • It will be trial and error, probably dictated by how you feel.
  • There are a few adverse effects from it, things like sensitivity at the injection site, headache, flu-like symptoms, and probably the most distressing would be a mild eyelid drooping, which would be temporary.
  • In rare instances, though, the FDA has noted that Botox might spread to other areas of your body.
  • If that happened, you could get botulism poisoning, which is life-threatening.
  • The symptoms of botulism poisoning include trouble swallowing, muscle weakness, or your muscles become easily tired, drooping of both eyelids, blurred vision or double vision, trouble breathing or speaking.
  • You can see these signs within hours or weeks.
  • If you notice any of these symptoms, it's crucial to reach out to your doctor right away or dial 911.
  • By the way, botulism poisoning is what you can get from contaminated canned foods.
  • You should be suspicious of this if you see a can that's leaking, dented, or bulging, or if you see foamy bubbles when you open the top.
  • In any of these cases, it's best to throw the can away and not even taste the food.
  • You only have to consume a small amount of botulinum toxin to experience the poisoning symptoms.
  • What you get with the Botox injection is a purified form of the botulinum toxin.
  • Maybe sometime in the future, this treatment will move from experimental to standard of care or will be easier to get, have it covered by your insurance, and we'll be able to know what to expect as far as how many injections you'll need.
  • But despite these limitations, it's still promising.
  • And if you are someone who has tried almost everything without good results or have trouble tolerating the standard antidepressant treatments, you should consider consulting a doctor about Botox injections to treat your depression symptoms.
  • Thanks for watching.
  • See you next time.