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Lithium vs. Antipsychotics: The Rise, Fall, and Rise Again of Lithium

Video vocabulary

have

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US / həv /

UK / hæv /

A1
  • verb
  • To drink, smoke, eat or use something
  • To experience the effects of something
  • To organize an event, or join in an activity
  • To own, possess, or hold something
  • To cause to happen or produce a particular effect

creativity

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US / ˌkri:eɪ'tɪvətɪ /

UK / ˌkrieˈtɪvətɪ /

A2
  • noun
  • Ability to imagine new ideas

last

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US / lɑ:st /

UK / læst /

A1
  • adjecitve
  • Most recent; the latest
  • The one before
  • adverb
  • Final; with nothing following; after all others
  • Most recent; the latest
  • determiner
  • The one at the end
  • verb
  • To remain or continue for a certain period of time

miracle

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US / 'mɪrəkl /

UK / ˈmɪrəkəl /

B1
  • noun
  • Amazing, seemingly impossible thing that happened

plan

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US / plæn /

UK / plæn /

A1
  • noun
  • Drawing of how something should be done or made

seep

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US / si:p /

UK / sip /

B2
  • verb
  • To flow slowly through small openings or pores

mechanism

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US / 'mekənɪzəm /

UK / ˈmɛkəˌnɪzəm /

B1
  • noun
  • Part of a machine that performs a certain function
  • System or process for achieving a certain result

substance

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US / 'sʌbstəns /

UK / ˈsʌbstəns /

A2
  • noun
  • Essence of; most basic or central qualities
  • Particular type of material
  • Having material form; existing
  • Quality of truth, importance, or meaningfulness

six

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US / sɪks /

UK / sɪks /

A1
  • number
  • 6

without

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US / wɪˈðaʊt /

UK / wɪðˈaʊt, wɪθ- /

A1
  • preposition
  • Not with; not having

blood

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US / blʌd /

UK / blʌd /

A2
  • adjecitve
  • Related by birth; family
  • noun
  • Red liquid in the bodies of people and animals
  • verb
  • To be initiated into something, e.g. a secret club

blur

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US / blɜ:(r) /

UK / blɚ /

B2
  • verb
  • To make something unclear or out of focus
  • To dull the distinction between things

away

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US / ə'weɪ /

UK / əˈwe /

A1
  • adjecitve
  • Not present
  • adverb
  • Disappear completely
  • Doing something with a lot of energy
  • Not here; far from here; in a different direction
  • To a different area, location

estimate

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US / 'estɪmət /

UK / ˈɛstəˌmet /

A2
  • noun
  • Guess or calculation of cost, size or value
  • verb
  • To guess or calculate the cost, size or value of

concentrate

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US / 'kɒnsntreɪt /

UK / ˈkɑnsənˌtret /

A2
  • verb
  • To cause to be present in large amount or number
  • To pay great attention to a task; focus
  • To remove water from a thing to make it more pure

month

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US / mʌnθ /

UK / mʌnθ /

A1
  • noun
  • One of 12 28-31 day periods in the year

confusion

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US / kən'fju:ʒən /

UK / kənˈfjuʒən /

B1
  • noun
  • Not knowing what to do; state of disorder

end

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US / end /

UK / ɛnd /

A1
  • noun
  • The point where a process or activity stops
  • A point that marks the limit of something; finish
  • Goal or desired result
  • The tip, edge or limit of something
  • verb
  • To be the last part of something

loss

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US / lɒs /

UK / lɔ:s /

A2
  • noun
  • Friend, family, or other loved person's death
  • Decrease or decline in quantity or amount
  • Experience or state of failing to have or keep
  • A situation when you lose a game
  • Process of failing to have or keep something
  • Difficulty or trouble caused by someone's leaving
  • Situation when more money is spent than is earned

mark

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US / mɑ:k /

UK / mɑrk /

A2
  • noun
  • Person's name
  • A dirty spot or line on something
  • Grade or score given for homework
  • Line or symbol made when writing
  • Particular point on a scale of measurement
  • Grade, such as a student receives in school
  • Stain or spot on something
  • Sign or symbol of a quality of feeling
  • Written sign or symbol
  • verb
  • To put a dirty spot or line on something
  • To give a grade for homework
  • To indicate something with a sign or symbol
  • To make or leave a visible sign of (path, etc.)
  • (Animals) to go to the toilet to show your area
  • To write or draw a line on something

manage

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US / ˈmænɪdʒ /

UK / ˈmænɪdʒ /

A1
  • verb
  • To survive hardships and difficulties; to cope
  • To run or operate a business by directing others

remember

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US / rɪ'membə(r) /

UK / rɪˈmɛmbɚ /

A1
  • verb
  • To give someone a gift, e.g. birthday, wedding
  • To hold a thought in your mind to not forget it
  • To bring a previous image or idea to your mind

scene

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US / si:n /

UK / sin /

A2
  • noun
  • Incident where someone behaves angrily, badly
  • View that looks like a picture
  • Place where something particular happened
  • Part of an act in a play

mixed

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US / mɪkst /

UK / mɪkst /

A2
  • verb
  • To combine two or more things to make one
  • To meet and get along with others, e.g. at a party

process

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US / prə'ses /

UK / ˈprɑsˌɛs, ˈproˌsɛs /

A2
  • noun
  • Dealing with official forms in the way required
  • Set of changes that occur slowly and naturally
  • verb
  • To organize and use data in a computer
  • To deal with official forms in the way required
  • To prepare by treating something in a certain way
  • To adopt a set of actions that produce a result
  • To convert by putting something through a machine

with

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US / wɪð /

UK / wɪð, wɪθ /

A1
  • preposition
  • As an employee of a certain company
  • Against something or someone
  • By using something as a means
  • Due to; because of
  • Including
  • Possessing as a feature
  • Related to
  • (Of the manner/attitude by which you do something)
  • Used to express that people or things are together

hand

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US / hænd /

UK / hænd /

A1
  • noun
  • Cards given to a player in a card game
  • Piece of a clock that points to the time
  • Someone who performs physical tasks or work
  • Body part at the end of a person's arm
  • Help for someone performing a particular action
  • Condition of having power or influence
  • Member of the crew of a ship
  • verb
  • To give something to someone personally

next

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US / nekst /

UK / nɛkst /

A1
  • adverb
  • The one that follows another in time or order
  • At a time or place directly after the present one
  • noun
  • The one that follows after
  • adjecitve
  • Immediately after the previous one
  • First occurrence after the present one

problem

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US / ˈprɒbləm /

UK / ˈprɑbləm /

A1
  • adjecitve
  • Causing trouble
  • noun
  • Something difficult to deal with or causes trouble
  • Question to show understanding of a math concept

could

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US / kəd /

UK / kʊd /

A1
  • other
  • Past form of 'can' to mean have ability
  • Used to ask for something politely, or to offer

gold

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US / gəʊld /

UK / goʊld /

A2
  • noun
  • Soft yellow metal that is very valuable
  • Person's name
  • adjecitve
  • Dark yellow color often seen in sunsets

often

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US / ˈɔfən /

UK / ˈɔfən,ˈɑfən,ˈɔftən,ˈɑf- /

A1
  • adverb
  • Many times; frequently; on many occasions

reevaluate

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US / ri:ɪ'væljʊeɪt /

UK / ri:ɪ'væljʊeɪt /

B1
  • verb
  • To judge the value or something again

careful

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US / ˈkeəfl /

UK / ˈkerfl /

A2
  • adjecitve
  • Trying not to make mistakes; working slowly

century

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US / 'sentʃərɪ /

UK / ˈsɛntʃəri /

A1
  • noun
  • Period of 100 years

see

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US / si: /

UK / si /

A1
  • verb
  • To go on a date with someone
  • To predict whether something is, or will be true
  • To understand what someone says
  • To use your eyes to look at something
  • To visit a place often for sightseeing or pleasure
  • To visit or meet with someone
  • To find out by waiting or looking
  • To watch (a game, movie or TV show)

onto

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US / ˈɒntə /

UK / ˈɑnˌtu, -tə, ˈɔn- /

A1
  • preposition
  • Towards a certain direction/into a certain area

low

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US / ləʊ /

UK / lo /

A1
  • adjecitve
  • Having a small quantity, supply, or amount
  • Being unhappy or unpleasant in attitude
  • Not high; being near the ground, or bottom
  • (Of a voice, sound) being soft; quiet
  • noun
  • Situation of not having a lot of something

lithium

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US / ˈlɪθiəm /

UK / ˈlɪθiəm /

A1
  • noun
  • Soft silver-white univalent element of the alkali metal group; the lightest metal known; occurs in s

choice

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US / tʃɔɪs /

UK / tʃɔɪs /

A1
  • adjecitve
  • Of good quality or taste; desirable
  • noun
  • Decision between two or more possibilities

tedious

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US / ˈti:diəs /

UK / ˈtidiəs /

B2
  • adjecitve
  • Being uninteresting and taking a long time; boring

owl

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US / aʊl /

UK / aʊl /

B1
  • noun
  • Bird with large eyes that hunts at night

increase

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US / ɪn'kri:s /

UK / ɪnˈkris /

A1
  • noun
  • Fact of increasing; amount something grows by
  • verb
  • To make or become larger in size or amount

notice

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US / 'nəʊtɪs /

UK / ˈnotɪs /

A1
  • noun
  • Time by when you must leave, e.g. if you are fired
  • Paper with an announcement, e.g. pinned to a board
  • verb
  • To become aware by sight, touch, or hearing

full

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US / fʊl /

UK / fʊl /

A1
  • adjecitve
  • Containing all the parts; complete
  • Containing or holding as much as possible
  • Having had enough food
  • adverb
  • In a direct manner; completely

decade

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US / ˈdekeɪd /

UK / ˈdɛkˌed, dɛˈked /

B1
  • noun
  • Period of 10 years

versus

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US / ˈvə:səs /

UK / ˈvɚsəs, -səz /

A2
  • preposition
  • Used to show that two things are competing

than

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US / ðən /

UK / ðən /

A1
  • conjunction
  • Used to compare two things that are not equal

root

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US / ru:t /

UK / rut, rʊt /

A2
  • noun
  • Emotional connection with a place, history etc.
  • The origin or starting place of something
  • A number that is multiplied by itself
  • Part of plant growing underground, as to get water
  • Part of tooth, hair etc. from which the rest grows
  • Base part of a word to which affixes can be added
  • verb
  • To cause a plant to develop or grow roots
  • (Animals) to search for e.g. food in earth
  • To stop someone moving, as through fear

revolutionize

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US / ˌrevə'lu:ʃənaɪz /

UK / revəˈluːʃəˌnaɪz /

B1
  • verb
  • To completely change so that it is much better

revisit

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US / ˌri:ˈvɪzɪt /

UK / riˈvɪzɪt /

B1
  • verb
  • To talk or think about something again
  • To visit some place or someone again

one

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US / wʌn /

UK / wʌn /

A1
  • pronoun
  • You; we; people in general; someone
  • The thing or person previously referred to
  • adjecitve
  • Used to refer to people generally
  • Being a strong example of (something mentioned)
  • number
  • Number 1

hydrate

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US / 'haɪdreɪt /

UK / ˈhaɪˌdret /

C2
  • verb
  • To give or add water to something or someone

other

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US / 'ʌðə(r) /

UK / ˈʌðər /

A1
  • adjecitve
  • A thing different from that mentioned
  • determiner
  • (Something) else; not the first (one)
  • pronoun
  • Being the one and only thing of that category

noticeable

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US / ˈnəʊtɪsəbl /

UK / ˈnoʊtɪsəbl /

B1
  • adjecitve
  • Being easy or likely to be sensed or noticed

john

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US / dʒɔn /

UK / dʒɑn /

A1
  • noun
  • A toilet.
  • A prostitute's client.
  • proper noun
  • (1165–1216), son of Henry II and Eleanor of Aquitaine; king of England 1199–1216; known as John Lack
  • The name of six kings of Portugal.

lead

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US / li:d /

UK / lid /

A1
  • adjecitve
  • Being the main part in movies or plays
  • noun
  • Wire for electricity, computer, etc.; cable
  • Information that could help to solve a crime
  • Main part in a play or movie
  • Heavy, gray metal element
  • Rope used to tie something to stop it escaping
  • Act of being at the front in a race or game
  • verb
  • To show the way or guide others
  • To be at the front of a race or game
  • To travel in front of; go in advance of others

into

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US / 'ɪntə /

UK / ˈɪntu /

A1
  • preposition
  • Moving or going inside something
  • In the same direction as; in the direction of
  • So as to become; taking the state of

interfere

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US / ˌɪntə'fɪə(r) /

UK / ˌɪntɚˈfɪr /

B1
  • verb
  • To get involved in something not your business

australian

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US / ɒˈstreɪliən /

UK / ɔˈstreljən /

A1
  • adjecitve
  • Concerning the culture and people of Australia
  • noun
  • People from Australia

clearing

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US / ˈklɪərɪŋ /

UK / ˈklɪrɪŋ /

A1
  • noun
  • An area in a forest without trees
  • verb
  • To recover from or remove a problem
  • To get rid of the entire contents of
  • To give permission for something to happen
  • To make a place or surface empty by removing
  • To prove that someone is not guilty or to blame

sake

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US / seɪk /

UK / sek /

A2
  • noun
  • Japanese rice wine
  • Interest or benefit of someone or something

quench

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US / kwentʃ /

UK / kwɛntʃ /

C1
  • verb
  • To put out a fire
  • To satisfy a desire (e.g. thirst by drinking)

less

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US / les /

UK / lɛs /

A1
  • adjecitve
  • Smaller in amount or degree
  • adverb
  • To a smaller degree
  • noun
  • A smaller amount
  • preposition
  • With the subtraction of

although

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US / ɔ:lˈðəu /

UK / ɔlˈðo /

A1
  • conjunction
  • Despite the fact that; however

you

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US / jʊ /

UK / ju /

A1
  • pronoun
  • Person someone is speaking or writing to
  • Person or people in general

year

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US / jə: /

UK / jɪr /

A1
  • noun
  • Unit of time equal to 12 months or 365 or 366 days
  • Used to refer to the age of a person

thyroid

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US / ˈθaɪrɔɪd /

UK / ˈθaɪˌrɔɪd /

A1
  • adjecitve
  • Of thyroid gland or cartilage in neck or throat

how

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US / haʊ /

UK / haʊ /

A1
  • adjecitve
  • To what degree? in what amount?
  • adverb
  • (Used to explain the way to do something)
  • exclamation
  • For what purpose or reason?
  • (Used to ask someone or something's condition)

hormone

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US / 'hɔ:məʊn /

UK / ˈhɔrˌmon /

B2
  • noun
  • Chemical produced by the body to control functions

extinguish

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US / ɪk'stɪŋɡwɪʃ /

UK / ɪkˈstɪŋɡwɪʃ /

B1
  • verb
  • To make something stop burning
  • To make something end or die

depression

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US / dɪ'preʃn /

UK / dɪˈprɛʃən /

B2
  • noun
  • Medical condition of a lack of vitality
  • Period of unemployment and low economic activity

also

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US / 'ɔ:lsəʊ /

UK / ˈɔlso /

A1
  • adverb
  • In addition; too; in a similar way

colleague

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US / 'kɒli:ɡ /

UK / ˈkɑlˌiɡ /

A2
  • noun
  • Person you work or cooperate with

bleed

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US / bli:d /

UK / blid /

A2
  • verb
  • To allow a liquid or gas to escape
  • To drain something such as water from a source
  • To flow out of something
  • (Of a wound, cut knee, etc.) to flow with blood
  • To take money from someone a little at a time

treat

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US / tri:t /

UK / trit /

A1
  • noun
  • Something you buy for others as a surprise present
  • something that tastes good and that is not eaten often
  • verb
  • To pay for the food or enjoyment of someone else
  • To use medical methods to try to cure an illness
  • To act in a certain way toward someone

shoelace

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US / ˈʃu:leɪs /

UK / ˈʃuˌles /

C2
  • noun
  • String used for fastening shoes

make

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US / meɪk /

UK / mek /

A1
  • noun
  • Product made by a particular company; brand
  • verb
  • To arrange or prepare something e.g. dinner
  • To get to (a place) on time
  • To gain the status of (teacher, lawyer, etc.)
  • To create something by putting things together
  • To earn a certain amount of money at a job
  • To cause or force a person to do something
  • To cause something to happen or be formed

average

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US / 'ævərɪdʒ /

UK / ˈævərɪdʒ, ˈævrɪdʒ /

A2
  • adjecitve
  • Typical or normal; usual; ordinary
  • noun
  • Total of numbers divided by the number of items
  • verb
  • To add numbers then divide by the number of items

body

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US / ˈbɒd.i /

UK / ˈbɑdi /

A1
  • noun
  • An object distinct from other objects
  • A group of people involved in an activity together
  • Main part of something
  • A person's physical self

bank

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US / bæŋk /

UK / bæŋk /

A1
  • noun
  • A financial institution that keeps or lends money
  • The side of a river
  • A row of things in lines (e.g. computers)
  • verb
  • To put or keep your money in a bank
  • To turn a plane when flying; (of a plane) to turn

three

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US / θri: /

UK / θri /

A1
  • number
  • Number 3

transport

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US / ˈtrænspɔ:t /

UK / ˈtrænspɔ:rt /

A2
  • noun
  • Very strong uncontrollable emotion, e.g. delight
  • Vehicle used to take soldiers to other places
  • verb
  • To carry things from one place to another
  • To cause to feel you are in a previous time

thirsty

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US / 'θɜ:stɪ /

UK / ˈθɚsti /

B1
  • adjecitve
  • Having a powerful desire or need for something
  • Needing to drink something

able

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US / 'eɪbl /

UK / ˈebəl /

A2
  • adjecitve
  • Skilled; good at something
  • Having the ability to do something

this

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US / ðɪs /

UK / ðɪs /

A1
  • adjecitve
  • Used to indicate something already been discussed
  • Used to indicate something happening around now
  • adverb
  • An indication by a physical motion or gesture
  • A specific amount of
  • determiner
  • Person, thing, or idea near you
  • pronoun
  • Person, thing that has already been discussed

may

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US / meɪ /

UK / me /

A1
  • noun
  • 5th month of the year
  • other
  • Used to express a desire
  • Expresses permission, possibility or probability
  • Used to show that a thing could be true

discuss

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US / dɪˈskʌs /

UK / dɪˈskʌs /

A1
  • verb
  • To talk about seriously or in great detail

flip

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US / flɪp /

UK / flɪp /

B2
  • noun
  • Act of turning your body in the air; somersault
  • Movement of something from one position to another
  • verb
  • To turn your body in the air, as in gymnastics
  • To move into a different position quickly
  • To move a button or switch to turn on or off

awake

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US / əˈweɪk /

UK / əˈwek /

A2
  • adjecitve
  • Not asleep; up; alert
  • verb
  • To make aware of (a certain feeling or memory)
  • To wake from sleep; wake someone from sleep

wane

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US / weɪn /

UK / wen /

B2
  • verb
  • To become smaller, weaker or less

state

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US / steɪt /

UK / stet /

A1
  • adjecitve
  • Concerning region within a country
  • noun
  • Region within a country, with its own government
  • Situation or condition something is in
  • verb
  • To say; declare as fact

level

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US / 'levl /

UK / ˈlɛvəl /

A2
  • adjecitve
  • (Sports) equal to another
  • Being steady and determined (e.g. a voice)
  • noun
  • Specific height of something
  • Amount of ability you have compared to others
  • Floor or deck within a building
  • Tool used to determine if something is lying flat
  • verb
  • To aim a gun at someone
  • To destroy a building; flatten an area completely
  • To make things flat or even
  • To make a score equal to another, in sports

genetic

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US / dʒəˈnetɪk /

UK / dʒəˈnɛtɪk /

B1
  • adjecitve
  • Of, relating to, or controlled by genes

crave

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US / kreɪv /

UK / krev /

B2
  • verb
  • To have a very strong desire for something

half

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US / hɑ:f /

UK / hæf, hɑf /

A1
  • adjecitve
  • Not complete
  • adverb
  • Partly; somewhat
  • noun
  • One of two equal periods of game time in a sport
  • The part you get when one is divided into two;

effective

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US / ɪˈfektɪv /

UK / ɪˈfɛktɪv /

A1
  • adjecitve
  • Working efficiently to produce a desired result

essential

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US / ɪ'senʃl /

UK / ɪˈsɛnʃəl /

A2
  • adjecitve
  • Extremely or most important and necessary

chemical

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US / ˈkemɪkl /

UK / ˈkɛmɪkəl /

A2
  • adjecitve
  • Made of various elements
  • noun
  • Basic substance produced by mixing elements

circadian

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US / sɜ:ˈkeɪdiən /

UK / sɜ:rˈkeɪdiən /

A1
  • noun
  • Concerning biological processes occurring at -hour intervals

vomit

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US / ˈvɒmɪt /

UK / ˈvɑ:mɪt /

B2
  • noun
  • Food coming back up from stomach, due to illness
  • verb
  • To bring (blood, etc.) up and out of mouth

urine

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US / ˈjʊərɪn /

UK / ˈjʊrən /

C1
  • noun
  • Yellow liquid waste from the body

the

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US / ðə /

UK / ðə /

A1
  • article
  • Used to refer to something already mentioned
  • Used to show there is only one of something
  • determiner
  • Used to describe all of a family

rocket

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US / 'rɒkɪt /

UK / ˈrɑkɪt /

B1
  • noun
  • Powerful engine that releases hot gases
  • Dark green, hot-tasting salad leaf
  • Weapon shaped like a long tube carrying bombs
  • Vehicle transporting people or things into space
  • verb
  • To travel, increase, or rise very quickly

researcher

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US / rɪ'sɜ:tʃə(r) /

UK / rɪˈsətʃɚ /

A2
  • noun
  • Someone who works to find new facts and ideas

rate

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US / reɪt /

UK / ret /

A1
  • noun
  • Current price or cost of something
  • Speed or frequency of events over time
  • verb
  • To assess something or consider its qualities

little

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US / 'lɪtl /

UK / ˈlɪtl /

A1
  • adjecitve
  • Being short in length of time
  • Not great in size, amount, or degree; small
  • Being very young or younger than others
  • adverb
  • By an amount or degree that is not very much
  • Not often; rarely
  • noun
  • A person's name

newly

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US / ˈnu:li:, ˈnju:- /

UK / ˈnuli, ˈnju- /

A2
  • adverb
  • Very recently; just done or made

let

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US / let /

UK / lɛt /

A1
  • verb
  • To allow someone to do something
  • Introducing a suggestion to do something together
  • To rent a house, etc. to others

downstream

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US / ˌdaʊn'stri:m /

UK / ˈdaʊnˌstrim /

C1
  • adverb
  • In the direction of a stream's current

big

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US / bɪɡ /

UK / bɪɡ /

A1
  • adjecitve
  • Popular
  • Serious
  • Large

true

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US / tru: /

UK / tru: /

A1
  • adjecitve
  • Agreeing with the facts; not false; real or actual

shiny

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US / ˈʃaɪni /

UK / ˈʃaɪni /

A2
  • adjecitve
  • Reflecting a lot of light; bright and smooth
  • Bright because of producing light

popular

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US / ˈpɒpjələ(r) /

UK / ˈpɑ:pjələ(r) /

A1
  • adjecitve
  • Liked or enjoyed by many people

mild

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US / maɪld /

UK / maɪld /

A2
  • adjecitve
  • Gentle in nature or behavior
  • Being neither too cold nor too hot

consider

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US / kən'sɪdə(r) /

UK / kənˈsɪdər /

A1
  • verb
  • To think carefully about something

sweat

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US / swet /

UK / swɛt /

A2
  • noun
  • An amount of hard work
  • (Of work, job) hard; needing effort
  • Liquid from your skin when you are hot or nervous
  • verb
  • To do an amount of hard work
  • To be worried or anxious about something
  • To produce drops of water from your skin when hot

should

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US / ʃʊd /

UK / ʃʊd /

A1
  • other
  • Used to indicate what is proper or reasonable

shift

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US / ʃɪft /

UK / ʃɪft /

A2
  • adjecitve
  • (Of work) starting at a certain time, as at night
  • noun
  • A change in a persons plans, opinions or beliefs
  • Period of work starting at a certain time
  • verb
  • To change in position or direction
  • To move something from one place to another

medical

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US / ˈmedɪkl /

UK / ˈmɛdɪkəl /

A2
  • adjecitve
  • Of or relating to physical health or medicine
  • noun
  • A health check or test

ketamine

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US / ˈketəmiːn /

UK / ˈketəmiːn /

A1
  • noun
  • General anesthetic and tranquilizer (not a barbiturate) that is administered intravenously or intram

balance

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US / ˈbæləns /

UK / ˈbæləns /

A2
  • noun
  • Instrument for weighing things
  • Being stable; having equal weight on both sides
  • Money remaining after paying costs
  • verb
  • To be steady by having equal weight on both sides
  • To make two or more things equal

age

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US / eɪdʒ /

UK / edʒ /

A1
  • verb
  • To keep food, wine for a long time to improve it
  • To get older
  • noun
  • Period of time in history
  • Number of years a person or thing has lived

third

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US / θɜ:d /

UK / θɜ:rd /

A1
  • adjecitve
  • 3rd: Number after second

switch

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US / swɪtʃ /

UK / swɪtʃ /

A2
  • noun
  • A change or shift from one method to another
  • Thing you move to turn electrical items on or off
  • Thin flexible piece of wood or stick
  • verb
  • To exchange or replace something for another thing

gene

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US / dʒi:n /

UK / dʒin /

B1
  • noun
  • Part of cell controlling development of a thing

develop

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US / dɪ'veləp /

UK / dɪˈvɛləp /

A1
  • verb
  • To explain something in steps and in detail
  • To create or think of something
  • To grow bigger, more complex, or more advanced
  • To make a photograph from film

day

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US / deɪ /

UK / de /

A1
  • noun
  • A period of 24 hours beginning at midnight
  • The period of time when it is light outside
  • Person's name

associate

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US / ə'səʊʃɪeɪt /

UK / əˈsoʊʃiˌeɪt /

B1
  • adjecitve
  • Part of a job title indicating a junior position
  • noun
  • Partner in professional work, e.g. in law
  • verb
  • To spend time with other people; mix with
  • To form a connection in your mind between things

wait

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US / weɪt /

UK / wet /

A1
  • verb
  • To delay or not do something until later
  • To spend time until an expected thing happens
  • To remain in a place until a thing happens

toxic

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US / ˈtɒksɪk /

UK / ˈtɑksɪk /

B2
  • adjecitve
  • Poisonous; harmful
  • (Of relationships) harmful; causing conflict

safe

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US / seɪf /

UK / sef /

A2
  • noun
  • Metal box with a lock to keep valuable things in
  • adjecitve
  • Highly likely
  • Being out of danger

once

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US / wʌns /

UK / wʌns /

A1
  • adverb
  • One time; one instance
  • At a time in the past
  • conjunction
  • When; as soon as

matter

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US / 'mætə(r) /

UK / ˈmætɚ /

A1
  • noun
  • Material all things are made of that fills space
  • Problem or reason for concern
  • verb
  • To be of great importance; to count

million

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US / ˈmɪljən /

UK / ˈmɪljən /

A1
  • number
  • 1,000,000

four

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US / fɔ:(r) /

UK / fɔr, for /

A1
  • number
  • 4

diabete

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US / /

UK / /

A1

divide

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US / dɪ'vaɪd /

UK / dɪˈvaɪd /

A2
  • verb
  • To split numbers by another number, e.g. 6 / 2 = 3
  • To separate something into equal pieces

bedtime

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US / ˈbedtaɪm /

UK / ˈbɛdˌtaɪm /

C1
  • noun
  • Time you go to bed

sodium

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US / 'səʊdɪəm /

UK / ˈsodiəm /

B2
  • noun
  • A soft, white chemical element

use

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US / ju:s /

UK / ju:s /

A1
  • noun
  • Ability to employ something
  • Need to enable it to work
  • Permission to do something with something
  • Act of spending money
  • Operation of a machine for its function
  • verb
  • To have; to eat, drink, consume etc.
  • To need to operate or work
  • To operate a machine, e.g. a computer
  • To treat a person badly
  • To do something with, for a task or purpose

speak

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US / spi:k /

UK / spik /

A1
  • verb
  • To be able to use a certain language
  • To use words to tell information, express thoughts

rough

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US / rʌf /

UK / rʌf /

A2
  • adjecitve
  • Causing or involving violence, force, and harm
  • (Of situations) tough; difficult to get through
  • Being imprecise, inexact, and not detailed
  • Not gentle or not soft
  • Having an uneven or not smooth surface
  • Raw and natural
  • (Of sea weather etc.) not calm with strong winds
  • Involving or causing sudden, forceful movements
  • adverb
  • In a manner that is difficult, or violent
  • noun
  • Violent, loud, and unpleasant person
  • Incomplete drawing or draft done lacking detail
  • verb
  • To make something less smooth

entry

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US / ˈentri /

UK / ˈɛntri /

A1
  • noun
  • Act of entering a room, building, party
  • Act of starting a career
  • Person or thing included in a competition or race
  • Piece of information entered into a computer
  • Place where one enters a building, stadium etc.
  • Piece of information in a database, dictionary etc.

actually

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US / ˈæktʃuəli /

UK / ˈæktʃuəli /

A1
  • adverb
  • Used to add new (often different) information

soda

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US / ˈsəʊdə /

UK / ˈsoʊdə /

B2
  • noun
  • Sweet bubbly flavored drink

small

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US / smɔ:l /

UK / smɔl /

A1
  • adjecitve
  • Little in size; not big
  • (Of letters) not written in capital letters
  • Being insignificant or minor
  • (Of a business) with few people or things; local
  • (Of voice) being soft and quiet
  • (Of a child) being young

production

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US / prəˈdʌkʃn /

UK / prəˈdʌkʃən, pro- /

A2
  • noun
  • Process of producing or growing food naturally
  • Process of making something on a large scale
  • Process of making a movie or TV show

new

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US / nju: /

UK / nu, nju /

A1
  • adjecitve
  • Not old, recently born, built or made
  • Being or doing something for the first time
  • Not felt, seen or known previously
  • Having been recently bought or obtained

nausea

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US / ˈnɔ:ziə /

UK / ˈnɔziə, -ʒə, -siə, -ʃə /

B2
  • noun
  • Feeling of sickness so that you feel like vomiting

here

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US / hɪə(r) /

UK / hɪr /

A1
  • adverb
  • In this place; at this location, position or time

cade

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US / ˈkædi /

UK / ˈkædi /

A1

clock

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US / klɒk /

UK / klɑ:k /

A1
  • noun
  • A device that shows the time
  • verb
  • To measure the time something takes

will

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US / wɪl /

UK / wɪl /

A1
  • noun
  • Desire or choice of someone
  • Document saying who gets your money when you die
  • Strong desire to do something; determination
  • Desire to do something; strong wish to do
  • other
  • Used with verbs to express the future
  • verb
  • To leave property to someone after your death
  • To use mental effort to make something happen
  • Am (is, are) likely to do
  • To influence someone to do something
  • To make something happen by strongly wanting it

metabolize

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US / mə'tæbəlaɪz /

UK / mə'tæbəlaɪz /

C2
  • verb
  • (Of the body) to convert food into energy

episode

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US / 'epɪsəʊd /

UK / ˈɛpɪˌsod /

B1
  • noun
  • One separate event in a series of events
  • Show which is part of a larger story

drug

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US / drʌɡ /

UK / drʌɡ /

A2
  • noun
  • Illegal substance taken for effect on the mind
  • Chemical used as a medicine
  • verb
  • To give drugs to someone to make them sleep

fluid

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US / 'flu:ɪd /

UK / ˈfluɪd /

B2
  • adjecitve
  • A material that can easily flow, e.g. water
  • Able to move smoothly or gracefully
  • Changing often and without warning
  • noun
  • Liquid that flows smoothly, such as water

diet

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US / 'daɪət /

UK / ˈdaɪɪt /

A2
  • noun
  • Plan of eating to reduce weight or improve health
  • other
  • The usual food and drink consumed by an organism (person or animal)
  • verb
  • To eat special or less food, as to lose weight

after

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US / 'ɑ:ftə(r) /

UK / ˈæftɚ /

A1
  • adverb
  • Later than another time, or behind something
  • conjunction
  • Following something before
  • preposition
  • When an event happened or time has passed

too

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US / tu: /

UK / tu /

A1
  • adverb
  • In addition, also; with emphasis
  • Say that something is more than you want

side

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US / saɪd /

UK / saɪd /

A1
  • adjecitve
  • In addition to the central or most important thing
  • Next to, or very close to, the right or left of
  • noun
  • Position or opinion that is opposite to another
  • Right or left part of a person's body
  • Feature of someone's personality
  • Straight edge of an object
  • One of two or more groups fighting each other
  • verb
  • To decide to agree with one point, not the other

reason

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US / 'ri:zn /

UK / ˈrizən /

A1
  • noun
  • Ability to think about facts and form a judgment
  • Explanation for why something occurred or was done
  • verb
  • To think and make conclusions in a logical manner

feel

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US / fi:l /

UK / fil /

A1
  • verb
  • To be aware of or experience an emotion, sensation
  • To sense through direct contact; touch

talk

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US / tɔ:k /

UK / tɔk /

A1
  • noun
  • Style of speaking
  • Discussion between two countries
  • Giving information in front of people; lecture
  • Saying things or ideas to someone with words
  • verb
  • To make a formal speech about something
  • To say things or ideas to someone with words

instability

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US / ˌɪnstəˈbɪləti /

UK / ˌɪnstəˈbɪlɪti /

B1
  • noun
  • Condition of being changeable

range

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US / reɪndʒ /

UK / rendʒ /

A2
  • noun
  • Cooking stove with multiple burners
  • Given distance from a point; how far plane can fly
  • Large grassy area where cattle wander and feed
  • Group or chain of mountains
  • Set of things with something in common
  • Limits within which something extends or varies
  • A set of products, e.g. so that people can choose
  • verb
  • To cover an area from one point to another
  • To extend to or vary within given limits
  • To put things in a row or in line
  • To wander or explore

just

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US / dʒʌst /

UK / dʒʌst /

A1
  • adjecitve
  • Proper or appropriate; as is deserved
  • Doing or being what is right or fair
  • Legally correct; having enough evidence
  • adverb
  • Almost; nearly
  • Exactly at the time of
  • Exactly (the same as, like)

line

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US / laɪn /

UK / laɪn /

A1
  • noun
  • Border that divides two places or regions
  • Long crease in the skin, often from age
  • Mark that is long, straight and very thin
  • Row of words, letters or numbers that are written
  • Telephone connection
  • People waiting one behind the other; queue
  • Long thin wire, e.g. for electrical signal
  • verb
  • To put material along the inside of something

gland

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US / ɡlænd /

UK / ɡlænd /

B2
  • noun
  • Organ that produces substances for the body to use

why

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US / waɪ /

UK / hwaɪ, waɪ /

A1
  • adverb
  • Question word to ask for a reason
  • exclamation
  • (Used to express surprise or approval)

tolerate

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US / ˈtɒləreɪt /

UK / ˈtɑ:ləreɪt /

B1
  • verb
  • To be able to adjust to changes of various kinds
  • To be able to survive under specific conditions
  • To let people do, say or believe what they wish
  • To be able to drink (e.g. alcohol) without effects

time

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US / taɪm /

UK / taɪm /

A1
  • noun
  • Speed at which music is played; tempo
  • Point as shown on a clock, e.g. 3 p.m
  • Number of hours, minutes needed to do something
  • Occasion when something happens
  • Period or occasion that something occurred
  • Period in history or the past
  • Something measured in minutes, hours, days, etc.
  • How long an event takes; duration
  • verb
  • To check speed at which music is performed
  • To choose a specific moment to do something
  • To measure how long an event takes, e.g. a race
  • To schedule something to occur at a specific moment

short

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US / ʃɔ:t /

UK / ʃɔrt /

A1
  • adverb
  • Less than what is needed
  • Suddenly stopping what you are saying or doing
  • verb
  • (Of electric circuit) to spark because faulty
  • adjecitve
  • Measuring a small distance
  • Happening for a small amount of time
  • Unfriendly or rude

for

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US / fə(r) /

UK / fɔr,fə /

A1
  • preposition
  • Used to show the purpose, or need of something

frequently

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US / ˈfri:kwəntli /

UK / ˈfrikwəntlɪ /

A2
  • adverb
  • Often; regularly

compound

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US / 'kɒmpaʊnd /

UK / kɑmˈpaUnd /

B1
  • adjecitve
  • (Of a term) created by combining two or more words
  • noun
  • Series of buildings that are walled or fenced off
  • Chemical made up of several others
  • Closed walled area, as in a prison
  • Something formed by combining elements/parts
  • Term created by using two or more words together
  • verb
  • To pay interest on a loan including the interest
  • To make something from various parts or components
  • To make a mistake or problem worse

analogy

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US / əˈnælədʒi /

UK / əˈnælədʒi /

B1
  • noun
  • Comparison of things based on their similarity

underappreciated

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US / ˌʌndərə'pri:ʃɪeɪtɪd /

UK / ˌʌndərə'pri:ʃɪeɪtɪd /

A1
  • adjecitve

usage

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US / ˈju:sɪdʒ /

UK / ˈjusɪdʒ, -zɪdʒ /

B2
  • noun
  • Amount something is used
  • Way something is actually used

window

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US / ˈwɪndəʊ /

UK / ˈwɪndoʊ /

A1
  • noun
  • Opening in a wall or door to let in light
  • Opening in a wall through which people do business

system

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US / 'sɪstəm /

UK / ˈsɪstəm /

A1
  • adjecitve
  • Working in an organized, logical way
  • noun
  • Set of organized, planned ideas that work together

standard

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US / 'stændəd /

UK / ˈstændəd /

A2
  • adjecitve
  • Being the accepted normal level of quality
  • (Of a language) being the most accepted in a place
  • noun
  • Official unit of measuring something
  • Principle of behaving in a moral way

sugary

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US / ˈʃʊgəri /

UK / ˈʃʊɡəri /

B1
  • adjecitve
  • Too sweet; insincere
  • Containing or having a taste like sugar

strong

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US / strɒŋ /

UK / strɔŋ /

A1
  • adjecitve
  • (Of tea or beer) dark or thick
  • Having big muscles; physically powerful

shrinkage

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US / ˈʃrɪŋkɪdʒ /

UK / ˈʃrɪŋkɪdʒ /

B1
  • noun
  • Fact of shrinking or becoming less or smaller

reconsider

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US / ˌri:kənˈsɪdə(r) /

UK / ˌrikənˈsɪdɚ /

B1
  • verb
  • To think whether to change an earlier decision

much

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US / mʌtʃ /

UK / mʌtʃ /

A1
  • adjecitve
  • Very; to a high level or degree
  • adverb
  • A lot; large amount; a high degree of
  • Nearly; basically
  • On many occasions; often
  • noun
  • A large amount; a great quantity

fact

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US / fækt /

UK / fækt /

A1
  • noun
  • Something that is known or proved to be true

few

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US / fju: /

UK / fju /

A1
  • pronoun
  • Not many, a small number

cold

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US / kəʊld /

UK / kold /

A1
  • adjecitve
  • Having a very low temperature
  • Being unfriendly or lacking emotion
  • noun
  • Illness of sneezing, coughing, and a sore throat

spouse

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US / spaʊs /

UK / spaʊs, spaʊz /

B2
  • noun
  • Someone's husband or wife

split

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US / splɪt /

UK / splɪt /

A2
  • adjecitve
  • No longer married or in a relationship
  • (Injured) by cutting it open, as in someone's lip
  • (Of a decision) when people cannot decide a winner
  • noun
  • Difference of opinion in a group causing a break
  • Separation or a break in something
  • verb
  • To become divided or broken along a straight line
  • To cause a cut in (lip, etc.)
  • To have difference of opinion in a group
  • To separate into two or more pieces
  • To divide something in an even or fair way

promise

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US / 'prɒmɪs /

UK / ˈprɑmɪs /

A1
  • verb
  • To say you will certainly do something

regularly

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US / ˈregjələli /

UK / ˈregjələrli /

B1
  • adverb
  • At the usual time each day, week, or month

generation

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US / ˌdʒenəˈreɪʃn /

UK / ˌdʒɛnəˈreʃən /

A2
  • noun
  • Act or process of producing or causing something
  • People born and living at about the same time

diarrhoea

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US / ˌdaɪə'rɪə /

UK / ˌdaɪə'ri:ə /

C1
  • noun
  • Frequent and watery bowel movements

cognitive

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US / ˈkɒgnətɪv /

UK / ˈkɑɡnɪtɪv /

C1
  • adjecitve
  • The process of knowing and remembering

stable

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US / 'steɪbl /

UK / ˈstebəl /

A2
  • adjecitve
  • In a position where something does not fall over
  • Having a chemical state that is not easily changed
  • Reacting in an even way; having good mental health
  • In good condition, and not likely to deteriorate
  • noun
  • Group of racing horses that belong to one owner
  • verb
  • To put horses in a stable

period

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US / ˈpɪəriəd /

UK / ˈpɪriəd /

A1
  • noun
  • Set amount of time during which events take place
  • A way to emphasize what you will say
  • A full stop (.), marking the end of a sentence
  • A menstrual cycle
  • A set time for a class to be held

replace

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US / rɪ'pleɪs /

UK / rɪˈples /

A2
  • verb
  • To use instead of something else
  • To return an item to its original location

kidney

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US / 'kɪdnɪ /

UK / ˈkɪdni /

B2
  • noun
  • Body organ that cleans blood, producing urine

never

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US / 'nevə(r) /

UK / ˈnɛvɚ /

A1
  • adverb
  • Not ever; not at any time

joseph

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US / ˈdʒəuzif /

UK / ˈdʒozəf, -səf /

A1
  • noun
  • (New Testament) Husband of Mary and (in Christian belief)
  • other
  • Leader of the Nez Perce in their retreat from United States troops

manic

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US / 'mænɪk /

UK / ˈmænɪk /

C1
  • adjecitve
  • Very excited in an almost uncontrollable way

citrate

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US / 'sɪtreɪt /

UK / 'sɪtreɪt /

C2
  • noun
  • Salt or ester of citric acid

well

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US / wel /

UK / wɛl /

A1
  • adjecitve
  • Being in a fortunate, good condition or state
  • Healthy and in good condition
  • adverb
  • In an acceptable, proper, or successful manner
  • In a complete, total, or full manner
  • A great and considerable degree
  • In a successful way, in a good or satisfactory way
  • exclamation
  • Used to begin or continue a particular statement
  • Used to show you want to start saying something
  • Used to express that you are waiting for a reply
  • You say this to change the topic of a conversation
  • Used to indicate you are making a final remark
  • noun
  • Long deep hole in the ground to get water
  • verb
  • To cause your eyes to fill with tears

within

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US / wɪˈðɪn /

UK / wɪðˈɪn, wɪθ- /

A1
  • adverb
  • Inside the limits of an area, time or range
  • preposition
  • From the inside of something

test

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US / test /

UK / test /

A1
  • noun
  • A medical examination
  • Action to establish the truth or nature of
  • Examination; questions to measure knowledge
  • verb
  • To be given a medical examination
  • To try to establish the truth or nature of
  • To ask a series of questions to measure knowledge

start

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US / stɑ:t /

UK / stɑrt /

A1
  • noun
  • First time or place that a thing exists; beginning
  • First opportunity to achieve something, e.g. a job
  • Sudden action or movement because you are scared
  • other
  • Beginning of something in place or time
  • verb
  • To do, be or happen for the first time; begin
  • To turn something on

since

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US / sɪns /

UK / sɪns /

A1
  • adverb
  • At a point before the present time
  • conjunction
  • For this reason; because
  • preposition
  • From the time in the past that

specifically

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US / spəˈsɪfɪkli /

UK / spəˈsɪfɪkli /

A2
  • adverb
  • As regards a particular thing; closely related to
  • In particular

source

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US / sɔ:s /

UK / sɔrs, sors /

A2
  • adjecitve
  • Produces or provides what is wanted or needed
  • noun
  • Piece of information; a person giving information
  • Place from which something necessary comes
  • verb
  • To get, e.g. a raw material, from somewhere

milliequivalent

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US / /

UK / /

A1

die

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US / daɪ /

UK / daɪ /

A1
  • noun
  • Cube with dots numbering 1-6 on it used in games
  • verb
  • To cease to function or work
  • (Of a thing) to stop being used or done
  • (Of a person) to stop living

carb

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US / kɑːb /

UK / kɑːrb /

A1
  • noun
  • Short form of carbohydrate

struggle

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US / 'strʌɡl /

UK / ˈstrʌɡəl /

A2
  • noun
  • Strong efforts made to do something difficult
  • verb
  • To try very hard to do something difficult

nudge

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US / nʌdʒ /

UK / nʌdʒ /

B2
  • verb
  • To touch or push something gently

news

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US / nju:z /

UK / nu:z /

A1
  • noun
  • Broadcast on radio or TV about recent events
  • Information about recent events

difficult

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US / 'dɪfɪkəlt /

UK / ˈdɪfɪˌkʌlt, -kəlt /

A1
  • adjecitve
  • Hard; not easy; you need to work hard to do it

correct

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US / kə'rekt /

UK / kəˈrɛkt /

A2
  • adjecitve
  • Being suitable and appropriate for an occasion
  • True or accurate
  • verb
  • To fix a problem
  • To write marks on a piece of work to show mistakes
  • To punish in order to improve

check

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US / tʃek /

UK / tʃɛk /

A1
  • adjecitve
  • Decorated with squares made up of lines
  • noun
  • Paper showing how much you owe at a restaurant
  • Printed piece of paper you sign to pay for things
  • A mark on a form, equivalent to 'yes'; tick
  • Mark used to show that something is correct
  • Procedure to prevent errors or control something
  • verb
  • To confirm the details of something are correct
  • To leave your things with staff who look after it
  • To examine something to see if something is wrong
  • To examine in order to prevent errors/a problem

water

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US / 'wɔ:tə(r) /

UK / ˈwɔtɚ, ˈwɑtɚ /

A1
  • noun
  • Clear liquid that forms the seas, rivers and rain
  • Large area such as an ocean or sea
  • verb
  • (Of the eyes) to produce tears
  • (Mouth) to become wet at the thought of nice food
  • To pour liquids onto a plant to keep it alive

per

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US / pə(r) /

UK / pɚ /

A2
  • preposition
  • In the manner directed or suggested
  • For each; during each

pepsi

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US / ˈpɛpsi /

UK / ˈpɛpsi /

A1
  • other
  • Pepsi Cola is a trademarked cola

soon

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US / su:n /

UK / sun /

A1
  • adverb
  • At a time not long from now

milligram

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US / ˈmɪligræm /

UK / ˈmɪlɪˌɡræm /

B2
  • noun
  • One thousandth (1/1000) of a gram

overall

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US / ˌəʊvər'ɔ:l /

UK / ˈovɚˌrɔl /

A2
  • adjecitve
  • Viewed as a whole; in general, not as details

eight

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US / eɪt /

UK / et /

A1
  • number
  • 8

chromosome

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US / ˈkrəʊməsəʊm /

UK / ˈkroʊməsoʊm /

C2
  • noun
  • Cell structures that carry the genetic material

begin

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US / bɪ'ɡɪn /

UK / ˈbeɡɪn /

A1
  • verb
  • To do the first part of an action; to start

value

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US / 'vælju: /

UK / ˈvælju /

A1
  • noun
  • Importance you attach to something
  • Some information expressed as a number
  • Stated price of something; worth
  • verb
  • To place a high importance on something
  • To say how much money something is worth

normalize

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US / ˈnɔ:məlaɪz /

UK / ˈnɔ:rməlaɪz /

B2
  • verb
  • To make something normal or regular

least

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US / li:st /

UK / list /

A1
  • adverb
  • In the smallest or lowest way
  • noun
  • Something that is of the lowest or smallest degree

week

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US / wi:k /

UK / wik /

A1
  • noun
  • Period of seven days from Sunday to Saturday

what

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US / wɒt /

UK / hwɑt, hwʌt, wɔt, wʌt,hwət, wət /

A1
  • pronoun
  • Thing or things that; the same kind as
  • Used to emphasize something you are about to say
  • adjecitve
  • Used to refer to a particular amount, or number
  • Used to place emphasis on a particular quality
  • adverb
  • To a certain degree
  • determiner
  • Question words used for asking for information
  • exclamation
  • Used to express excitement, shock, or surprise
  • Used to ask people to repeat something they said

that

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US / ðæt /

UK / ðæt, ðət /

A1
  • adjecitve
  • The person or thing being talked about
  • Used to identify something both the speakers know
  • adverb
  • Used to reinforce adjectives and adverbs
  • To such a degree
  • conjunction
  • Used to connect a noun clause
  • Used to introduce an adverbial clause
  • Used to introduce a noun clause
  • determiner
  • Used as a noun to refer to something
  • pronoun
  • Referring an object far away
  • Used to refer to the relative pronoun ‘which’

people

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US / 'pi:pl /

UK / ˈpipəl /

A1
  • noun
  • Persons sharing culture, country, background, etc.
  • Men, Women, Children

like

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US / laɪk /

UK / laɪk /

A1
  • adjecitve
  • Being equal in status or kind to something else
  • Similar; the same
  • adverb
  • For example
  • preposition
  • Used as a filler; used to ad emphasis
  • In a way similar to the way something is done
  • Such as; for example
  • verb
  • To want to
  • To find something pleasing; to prefer something

health

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US / helθ /

UK / hɛlθ /

A1
  • noun
  • (Person, company) being in a good condition; well

different

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US / ˈdɪfrənt /

UK / ˈdɪfrənt /

A1
  • adjecitve
  • Not of the same kind; unlike other things

even

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US / 'i:vn /

UK / ˈivən /

A1
  • adjecitve
  • Being equal in influence, power, possibility etc.
  • Being divided equally or fairly
  • (Of teams/contest) with similar chances of success
  • Smooth, level, or regular
  • Can be divided by 2; ending in 2, 4, 6, 8, or 0
  • At a regular, equally steady manner
  • Remaining steady and unchanging
  • adverb
  • (When this is surprising) as well; too
  • (Used to compare two things/stress the difference)
  • verb
  • To make something level; to flatten
  • To make something equal

again

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US / ə'ɡen /

UK / əˈɡɛn /

A1
  • adverb
  • One more time, once more

about

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US / ə'baʊt /

UK / əˈbaʊt /

A1
  • adverb
  • To be ready to; going to
  • Nearly; approximately; roughly
  • Near; next to; close to
  • In every direction; in the area of
  • preposition
  • Concerning or of (a topic)

pill

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US / pɪl /

UK / pɪl /

A2
  • noun
  • Person who is difficult to deal with
  • Small, round piece of medicine that is swallowed

own

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US / əʊn /

UK / on /

A1
  • adjecitve
  • Belong to oneself
  • determiner
  • Yours, his, hers, etc.; not belonging to another
  • pronoun
  • (Something) belong to myself
  • verb
  • To have something as your property

hypothyroid

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US / ˌhaɪpəʊˈθaɪrɔɪd /

UK / ˌhaɪpoʊˈθaɪrɔɪd /

A1
  • adjecitve

evening

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US / ˈi:vnɪŋ /

UK / ˈivnɪŋ /

A1
  • noun
  • Last part of the day and early part of night
  • A social event in the early part of the night
  • verb
  • To make something level; to flatten
  • To make something equal

cause

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US / kɔ:z /

UK / kɔz /

A2
  • noun
  • Belief, goal or organization that people support
  • Reason for
  • verb
  • To make something happen; create effect or result

prominent

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US / ˈprɒmɪnənt /

UK / ˈprɑmənənt /

B1
  • adjecitve
  • Being important or well known
  • Being easily noticeable
  • Sticking out beyond something

liter

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US / 'li:tə(r) /

UK / ˈlitɚ /

A1
  • noun
  • Metric unit for measuring liquid or gas

each

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US / i:tʃ /

UK / itʃ /

A1
  • determiner
  • Every one of two or more things
  • pronoun
  • Per one person or thing

happen

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US / 'hæpən /

UK / ˈhæpən /

A1
  • verb
  • To take place or occur

alter

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US / ˈɔ:ltə(r) /

UK / ˈɔltɚ /

A2
  • verb
  • To change so (clothing) fits better

cell

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US / sel /

UK / sɛl /

A2
  • noun
  • Smallest unit of living things in biology
  • Group of people - often from a secret organization
  • Prisoner's room in a jail
  • Shortened form of 'cellphone'

watch

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US / wɒtʃ /

UK / wɑtʃ /

A1
  • noun
  • Period of time someone is responsible for guarding
  • Device you wear on your wrist that shows the time
  • Official warning statement, e.g. of bad weather
  • verb
  • To keep in check, manage, or control something
  • To look at something for entertainment, e.g. TV
  • To guard a place or people; protect child, etc.
  • To look at carefully to work out what is happening
  • To protect and care for someone or something

tend

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US / tend /

UK / tɛnd /

A2
  • verb
  • To move or act in a certain manner
  • To take care of
  • To regularly behave in a certain way

mean

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US / mi:n /

UK / min /

A1
  • adjecitve
  • Being good at
  • Nasty; unkind
  • Not liking to spend money; cheap; stingy
  • noun
  • Average of a set of numbers
  • verb
  • To express a particular idea or thought
  • To intend to do something in particular
  • To have a particular meaning or value

require

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US / rɪ'kwaɪə(r) /

UK / rɪˈkwaɪr /

A2
  • verb
  • To demand that someone does something
  • To need to do something, to make it necessary

offer

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US / 'ɒfə(r) /

UK / ˈɔfɚ, ˈɑfɚ /

A1
  • noun
  • Price you say you are willing to pay for something
  • Act of making a thing available to be accepted
  • verb
  • To suggest a price you are willing to pay
  • To give the opportunity to accept something
  • To say you are willing to do something
  • To give or say something as an act of worship

lab

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US / læb /

UK / læb /

B1
  • noun
  • Short for 'laboratory'

enough

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US / ɪˈnʌf /

UK / ɪˈnʌf /

A1
  • adjecitve
  • Sufficient to answer the need
  • adverb
  • To a satisfactory degree
  • pronoun
  • Equal to what is needed; as much as required
  • Adequate number or amount

energy

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US / 'enədʒɪ /

UK / ˈɛnədʒi /

A2
  • noun
  • Physical or mental strength

hassle

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US / ˈhæsl /

UK / ˈhæsəl /

B2
  • noun
  • Unpleasant task or chore harder than it should be
  • verb
  • To cause trouble or annoyance to someone

find

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US / faɪnd /

UK / faɪnd /

A1
  • noun
  • Object discovered by chance
  • Things that have been discovered from searching
  • verb
  • To become aware of something that is happening
  • To discover or meet by chance
  • To decide if someone is guilty of a crime, or not
  • To learn through study, research, or effort
  • To discover something by looking for it

great

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US / ɡreɪt /

UK / ɡret /

A1
  • adjecitve
  • Very large in size
  • Very important
  • Very good; fantastic; wonderful
  • adverb
  • Very good; better than before
  • noun
  • Successful and well-admired person

conclusion

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US / kənˈklu:ʒn /

UK / kənˈkluʒən /

A2
  • noun
  • End of something; finish
  • Judgment or opinion after thinking for a while
  • Opinion or final judgment at end of book, essay

vision

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US / 'vɪʒn /

UK / ˈvɪʒən /

A2
  • noun
  • Ability to see; eyesight
  • Something you see in your imagination or dreams
  • Ability to plan for the future of something

then

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US / ðen /

UK / ðɛn /

A1
  • adverb
  • A time that is not now
  • Following another thing in time or arrangement
  • Following on reasonably from what was just stated
  • At that time, not now

include

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US / ɪnˈklu:d /

UK / ɪnˈklud /

A1
  • verb
  • To make someone, something part of a group

during

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US / ˈdjʊərɪŋ /

UK / ˈdʊrɪŋ, ˈdjʊr- /

A1
  • preposition
  • At some point in the course of an event or thing

fire

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US / 'faɪə(r) /

UK / faɪr /

A1
  • noun
  • Heat and the flame produced when burning
  • Intense energy for or about something
  • verb
  • To apply heat to something to make it hard
  • To make a person leave their job; dismiss
  • To shoot a gun or weapon
  • To launch something into the sky, e.g. a rocket
  • To start working on something e.g. a project

annually

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US / ˈænjuəli /

UK / ˈænjʊəlɪ /

B1
  • adverb
  • Every year; once a year

block

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US / blɒk /

UK / blɑk /

A2
  • noun
  • Solid piece of material used for building
  • A piece of wood, chocolate etc.
  • Hard piece of wood, stone etc. with straight edges
  • Building made up of offices or apartments
  • Area of a city divided by four streets
  • verb
  • To stop from going forward or making progress

stay

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US / steɪ /

UK / ste /

A1
  • noun
  • Legal order to stop or delay an action
  • Strong rope or wire that supports a ship's mast
  • Period of time spent living in or visiting a place
  • verb
  • To keep trying without giving up
  • To remain in the same place and not move away
  • To spend time visiting a place or someone's home

shortening

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US / ˈʃɔ:tnɪŋ /

UK / ˈʃɔrtnɪŋ, ˈʃɔrtnɪŋ /

B1
  • verb
  • To make something, e.g. a skirt, shorter

lastly

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US / ˈlɑ:stli /

UK / ˈlæstli /

A2
  • adverb
  • In conclusion; at the final part of something

dose

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US / dəʊs /

UK / doʊs /

B1
  • noun
  • An amount of medicine to be taken at any one time
  • verb
  • To give a certain amount of something to someone

education

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US / ˌedʒuˈkeɪʃn /

UK / ˌɛdʒəˈkeʃən /

A2
  • noun
  • Academic field studying the practice of teaching
  • Process of giving or receiving teaching

second

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US / 'sekənd /

UK / ˈsɛkənd /

A1
  • adjecitve
  • 2nd; the one following first
  • noun
  • Unit of time; one sixtieth of a minute
  • Short period of time that you wait for someone
  • (Do) soon
  • verb
  • To agree to support a proposal at a meeting

roughly

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US / ˈrʌfli /

UK / ˈrʌflɪ /

B1
  • adverb
  • Approximately; (of numbers) about; around
  • In a manner that is violent or not careful
  • In an inexact, imprecise or violent way
  • In a basic, simple manner

spill

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US / spɪl /

UK / spɪl /

B1
  • noun
  • Accident when someone falls
  • Act of allowing a fluid to escape
  • verb
  • To come out of and spread beyond limits
  • To cause (blood) to flow from body, as by killing
  • To tell secrets or let information escape
  • To cause a liquid to fall out of its container
  • To come out of a holding container

medium

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US / 'mi:dɪəm /

UK / ˈmidiəm /

A2
  • noun
  • Method of expressing ideas or feelings
  • Something available in a middle size or condition
  • Person who claims to communicate with the dead

particularly

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US / pəˈtikjuləli /

UK / pɚˈtɪkjələli, pəˈtɪk- /

A2
  • adverb
  • Specially; more than others

hard

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US / hɑ:d /

UK / hɑː(r)d /

A1
  • adjecitve
  • Difficult to do; difficult to understand
  • (Of facts) not able to be misunderstood; clear
  • (Of alcohol) strong
  • Involving or requiring lots of work, effort, care
  • Being full of pain, trouble, and problems
  • Strong
  • (Of edge) clear; sharp
  • Difficult to bend, break or cut; solid
  • adverb
  • With lots of force, power, or impact

first

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US / fɜ:st /

UK / fɚst /

A1
  • adjecitve
  • 1st; Coming before all others in time or place
  • noun
  • Something that has not happened before
  • Position of the winner of a competition

get

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US / ɡet /

UK / ɡɛt /

A1
  • verb
  • To become affected by illness or disease
  • To begin to feel or understand an emotion or idea
  • To send or bring someone or something home, etc.
  • To go somewhere to obtain something
  • To (cause to) do a particular thing
  • To obtain, receive or be given something
  • To currently have
  • To prepare for use
  • To understand something being said or read

all

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US / ɔ:l /

UK / ɔl /

A1
  • adverb
  • Completely; totally
  • determiner
  • Being every one of something
  • pronoun
  • 100% of something; the complete amount

everyone

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US / ˈevriwʌn /

UK / ˈɛvriˌwʌn /

A1
  • pronoun
  • Every person; everybody

depressive

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US / dɪˈpresɪv /

UK / dɪˈprɛsɪv /

B2
  • adjecitve
  • Suffering a psychological lack of happiness

its

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US / ɪts /

UK / ɪts /

A1
  • adjecitve
  • Referring to or belonging to ‘it’
  • determiner
  • Of something; belonging or related to something
  • other
  • Possessive form of “it”

fast

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US / fɑ:st /

UK / fæst /

A1
  • adjecitve
  • In a way that is difficult to move or change
  • Moving or able to move quickly
  • Showing time that is later than the actual time
  • adverb
  • With a great deal of speed
  • noun
  • Period of time when a person chooses not to eat
  • verb
  • To refuse food for a long time

metabolic

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US / ˌmetə'bɒlɪk /

UK / ˌmetə'bɒlɪk /

B2
  • adjecitve
  • Concerning the body's metabolism

metabolism

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US / məˈtæbəlɪzəm /

UK / mɪˈtæbəˌlɪzəm /

B2
  • noun
  • Chemical processes to convert food to energy

remove

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US / rɪˈmu:v /

UK / rɪˈmuv /

A1
  • verb
  • To get rid of something completely
  • To make someone leave his or her job or position
  • To move, erase or take away from a place
  • To take something off (e.g. clothing)

produce

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US / prə'dju:s /

UK / prəˈdus, -ˈdjus, pro- /

A1
  • noun
  • Fresh foods such as fruits and vegetables
  • verb
  • To grow something naturally
  • To make something appear
  • To manufacture something using machines
  • To control the making a movie or television show

telomeres

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US / /

UK / /

A1
  • other

tiredness

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US / 'taɪədnəs /

UK / ˈtaɪrdnɪs /

B1
  • noun
  • Condition of lacking energy and wanting to rest

who

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US / hu: /

UK / hu /

A1
  • pronoun
  • Which person
  • Used to introduce information about people

account

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US / ə'kaʊnt /

UK / əˈkaʊnt /

A1
  • noun
  • An advantage
  • Arrangement with a bank to keep your money for you
  • An invoice for things bought
  • Arrangement whereby you can use online services
  • A description, often written, of events; report

department

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US / dɪˈpɑ:tmənt /

UK / dɪˈpɑ:rtmənt /

A2
  • noun
  • Division of a larger part or organization

main

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US / meɪn /

UK / men /

A1
  • adjecitve
  • Most important; most often used

pedestal

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US / 'pedɪstl /

UK / ˈpɛdɪstəl /

B2
  • adjecitve
  • Support or base as for a pillar or statue

pretty

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US / 'prɪtɪ /

UK / ˈprɪti /

A1
  • adjecitve
  • Being attractive to the eye in a simple way
  • adverb
  • Very; to a great degree

preventive

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US / prɪˈventɪv /

UK / prɪˈvɛntɪv /

B1
  • adjecitve
  • Done to stop something bad happening

several

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US / ˈsevrəl /

UK / ˈsɛvərəl,ˈsɛvrəl /

A1
  • adjecitve
  • Many of
  • pronoun
  • More than two but not a large amount

tremor

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US / ˈtremə(r) /

UK / ˈtrɛmɚ /

C1
  • noun
  • Trembling/shaking from body weakness, stress, etc.

build

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US / bɪld /

UK / bɪld /

A1
  • noun
  • Your physical shape; physique
  • verb
  • To establish e.g. a reputation, over time
  • To construct a house, office, factory

cap

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US / kæp /

UK / kæp /

B1
  • noun
  • Covering for the end or top of something
  • Small, soft hat often with a front visor or shade
  • An upper limit on the amount of (e.g. budget)
  • verb
  • To cover the top or end of an object
  • To limit the amount of usage of something

harmful

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US / ˈhɑ:mfl /

UK / ˈhɑ:rmfl /

A2
  • adjecitve
  • Likely to cause damage or injury

heavy

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US / 'hevɪ /

UK / ˈhɛvi /

A1
  • adjecitve
  • Greater in amount, degree, or severity than usual
  • Involving serious or strong emotions
  • Having a lot of weight

gain

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US / ɡeɪn /

UK / ɡen /

A2
  • noun
  • An increase in something, such as weight
  • verb
  • To increase in something, such as weight
  • To get something wanted, needed or valued

mineral

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US / 'mɪnərəl /

UK / ˈmɪnərəl /

B1
  • noun
  • Substance naturally formed in the ground

old

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US / əʊld /

UK / old /

A1
  • adjecitve
  • Having existed for a long time, not young or new
  • Age of a person since birth

work

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US / wɜ:k /

UK / wɚk /

A1
  • adjecitve
  • Activity completed in order to make money
  • noun
  • The product of some artistic or literary endeavor
  • Everything created by an author, artist, musician
  • Activity you do in order to make money
  • Place of employment
  • Final product or result of a some labor or effort
  • verb
  • To bring into a specific state of success
  • To be functioning properly, e.g. a car
  • To do your job in your company or workplace
  • To make an effort to do something
  • To operate a machine or device

bit

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US / bɪt /

UK / bɪt /

A1
  • noun
  • Device put in a horse's mouth to control it
  • Small piece of something
  • verb
  • (E.g. of fish) to take bait and be caught

believe

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US / bɪ'li:v /

UK / bɪˈliv /

A1
  • verb
  • To think or accept that something is true
  • To have a particular opinion about something

effectively

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US / ɪˈfektɪvli /

UK / ɪˈfɛktɪvli /

B1
  • adverb
  • In a way that produces the desired result

look

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US / lʊk /

UK / lʊk /

A1
  • noun
  • Person's beauty or physical attractiveness
  • Particular style of dress, clothes, or appearance
  • The way someone, something appears to be
  • Act of searching for or examining something
  • verb
  • To appear to be; seem

regular

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US / ˈregjələ(r) /

UK / ˈrɛɡjəlɚ /

A2
  • adjecitve
  • Having an equal amount of space or time in between
  • Occurring or being done frequently
  • Being normal, usual, or average
  • noun
  • Customers who frequently visit a place
  • Soldier who has a permanent job in the army

thank

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US / θæŋk /

UK / θæŋk /

A1
  • verb
  • To tell someone you are grateful to them

add

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US / æd /

UK / æd /

A1
  • verb
  • To include as well
  • To put two things or numbers together, e.g. 2+2

discover

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US / dɪˈskʌvə(r) /

UK / dɪˈskʌvɚ /

A2
  • verb
  • To find something new that was not known before

shadow

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US / 'ʃædəʊ /

UK / ˈʃædo /

A2
  • noun
  • Person who follows another person to observe them
  • Area of darkness that is caused by blocked light
  • verb
  • To cover something with shade
  • To secretly follow a person

take

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US / teɪk /

UK / tek /

A1
  • noun
  • Filming of a single scene for TV or the movies
  • verb
  • To accept something that is offered
  • To use a method of traveling, e.g. a bus or train
  • To use a camera to make (a photo)
  • To pick up something and go away with it
  • To study a subject in school
  • To attempt to pass (an exam)
  • To require a certain amount of time, money, space

tracy

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US / ˈtreisi /

UK / ˈtresi /

A1
  • proper noun
  • A commercial and industrial city in north central California, in the San Joaquin Valley; population

contender

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US / kənˈtendə(r) /

UK / kənˈtɛndɚ /

B2
  • noun
  • Athlete or team competing (and likely) to win

diagnose

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US / ˈdaɪəgnəʊz /

UK / ˌdaɪəgˈnoʊs /

B1
  • verb
  • To determine the cause of an illness or problem

heart

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US / hɑ:t /

UK / hɑrt /

A1
  • noun
  • A feeling of care for others; compassion
  • Courage, confidence, and emotional strength
  • Be cheerfully encouraging
  • Most essential, important, or central part
  • Referring to a promise or something important
  • State or feelings of affection or deep love
  • Core part of a vegetable, e.g. a lettuce
  • The part of the body that pumps blood
  • Place where emotions are believed to be felt
  • A shape that represents love

due

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US / dju: /

UK / du, dju /

A1
  • adjecitve
  • When something is required or expected
  • Owed to a person as a right
  • noun
  • Something you deserve; something you can expect

move

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US / mu:v /

UK / muv /

A1
  • noun
  • Act of moving a playing piece in chess, etc.
  • An action; doing something
  • Step taken to achieve a goal
  • verb
  • To cause someone to have certain emotions
  • To cause something to change to a different place
  • To change where people live or a business operates
  • To take action to do or achieve something

protective

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US / prəˈtektɪv /

UK / prəˈtɛktɪv /

A2
  • adjecitve
  • Serving to defend against harm or danger

their

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US / ðɛː /

UK / ðer /

A1
  • determiner
  • Belonging to them

symptom

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US / 'sɪmptəm /

UK / ˈsɪmtəm, ˈsɪmp- /

B1
  • noun
  • Sign that suggests that there is a problem

useful

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US / ˈju:sfl /

UK / ˈjusfəl /

A1
  • adjecitve
  • That can help with a particular task

way

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US / weɪ /

UK / we /

A1
  • adverb
  • Used to emphasize the amount of something
  • noun
  • Particular aspect of something being thought about
  • One of various choices that could be made
  • Particular existing condition or state
  • (Often long) distance or length of time
  • How something is done
  • Route to go to a place
  • Small street
  • Usual behavior, emotions or habits of someone

between

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US / bɪˈtwi:n /

UK / bɪˈtwin /

A1
  • preposition
  • From one person, thing, or place, to another
  • In the space that separates two objects
  • Among two or more people who share something

everything

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US / 'evrɪθɪŋ /

UK / ˈɛvriˌθɪŋ /

A1
  • pronoun
  • All of the things mentioned

device

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US / dɪˈvaɪs /

UK / dɪˈvaɪs /

A2
  • noun
  • Object, machine, or equipment for a specific use
  • Method of doing something; a way

gradually

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US / ˈgrædʒuəli /

UK / ˈɡrædʒʊəlɪ /

B1
  • adverb
  • Occurring in a slow manner over a period of time

medication

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US / ˌmedɪˈkeɪʃn /

UK / ˌmɛdɪˈkeʃən /

B2
  • noun
  • Substance to relieve pain or cure sickness

pepsico

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US / ˈpɛpsɪkoʊ /

UK / /

A1

risk

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US / rɪsk /

UK / rɪsk /

A1
  • noun
  • Actions that cause potential problems
  • verb
  • To do something potentially dangerous or foolish

they

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US / ðeɪ /

UK / ðe /

A1
  • pronoun
  • Two or more people, animals, or things

topic

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US / 'tɒpɪk /

UK / ˈtɑpɪk /

A2
  • noun
  • Subject or issue people talk or write about

very

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US / 'verɪ /

UK / ˈvɛri /

A1
  • adjecitve
  • Concerning a large degree or amount
  • adverb
  • A lot; much; many
  • Used to stress or emphasize a noun

sleep

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US / sli:p /

UK / slip /

A1
  • noun
  • Substance in a person's eyes after waking up
  • Period of time during which a person is asleep
  • verb
  • To have enough beds for
  • To rest your body in bed, as at night time

change

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US / tʃeɪndʒ /

UK / tʃendʒ /

A1
  • noun
  • Exchange of one set of clothes for another
  • Money in the form of coins instead of paper
  • Money returned after giving too much
  • Act of making or becoming something else
  • verb
  • To exchange one set of clothes for another
  • To exchange one kind of money for another
  • To replace something with another thing
  • To make or become something else
  • To go from one train, bus, etc. and go to another

bipolar

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US / ˌbaɪˈpəʊlə(r) /

UK / ˌbaɪˈpoʊlər /

B2
  • adjecitve
  • (Disorder) exhibiting extremes of behavior
  • Having two opposite poles

calcium

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US / 'kælsɪəm /

UK / ˈkælsiəm /

C2
  • noun
  • A substance important for making bones and teeth

cup

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US / kʌp /

UK / kʌp /

A1
  • noun
  • Small round container used for drinking
  • Silver trophy teams compete to win
  • Unit of measurement for foods or liquids
  • verb
  • To make the shape of a bowl with your hands

hold

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US / həʊld /

UK / hold /

A1
  • noun
  • Section of a ship or plane used for storing things
  • Influence or power held over someone
  • Place of support for hands or feet when climbing
  • verb
  • To agree to keep something for someone
  • To have the capacity to support/contain something
  • To control an area and protect it from attack
  • To not allow someone to leave a place
  • To cause an event to happen at a place or time
  • To use hands or arms to carry or keep something
  • To have a specific quality or property
  • To keep an image, belief or feeling in your mind
  • To have or own something
  • To wait before being able to talk on the phone
  • To limit the movement of someone in a sport

severe

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US / sɪ'vɪə(r) /

UK / səˈvɪr /

A2
  • adjecitve
  • Very bad; harsh
  • Being very serious or extremely bad
  • (Of clothes, etc.) plain; simple; not decorated

show

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US / ʃəʊ /

UK / ʃo /

A1
  • noun
  • False display of love, emotion or action
  • An event for displaying or promoting goods
  • Play, opera or theater production
  • Presentation that is broadcast on TV or radio
  • verb
  • To be easily seen or displayed
  • To display your emotions or feelings
  • To let someone see something; display
  • To explain or teach how something is done
  • To lead someone somewhere; point them to something
  • To prove something to be true, correct
  • To reveal or allow something to be seen

calorie

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US / 'kælərɪ /

UK / ˈkæləri /

B2
  • noun
  • Unit for measuring the amount of energy in food

capsule

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US / 'kæpsju:l /

UK / ˈkæpsul /

B2
  • adjecitve
  • Modifier a small version, with only key items
  • noun
  • Tube-shaped plastic casing filled with medicine
  • Part of a space craft where people live and work

any

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US / 'enɪ /

UK / ˈɛni /

A1
  • adjecitve
  • One, or some, no matter which
  • pronoun
  • One (thing) of many; some

atypical

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US / ˌeɪˈtɪpɪkl /

UK / eˈtɪpɪkəl /

C1
  • adjecitve
  • Not typical, not usual or normal

come

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US / kʌm /

UK / kʌm /

A1
  • verb
  • To arrive at a place
  • (Of mail) to be delivered
  • To move toward someone; go with someone
  • To reach a certain point or state

company

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US / 'kʌmpənɪ /

UK / ˈkʌmpəni /

A1
  • noun
  • Good feeling from being with someone else
  • A business that sells things or provides services
  • Guests, especially in your home
  • Being with another person rather than alone

help

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US / help /

UK / hɛlp /

A1
  • noun
  • Something given to enable a person to do something
  • Assistance given to someone in need
  • Someone who makes something easier or possible
  • verb
  • To act to enable a person to do something; assist
  • To make something better or less difficult

game

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US / ɡeɪm /

UK / ɡem /

A1
  • noun
  • Activity with rules that people play to have fun
  • Birds and animals people hunt to kill and eat
  • Match between two teams

think

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US / θɪŋk /

UK / θɪŋk /

A1
  • verb
  • To have an idea about something without certainty
  • To have an idea, opinion or belief about something

antidepressant

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US / ˌæntidɪˈpresnt /

UK / ˌæntidɪˈprɛsənt, ˌæntaɪ- /

C2
  • noun
  • Medicine used to treat depression

leave

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US / li:v /

UK / liv /

A1
  • noun
  • Permission to do something
  • Vacation time; time off work
  • verb
  • To go away from; depart
  • To gift property to someone after you die
  • To allow something to continue happening
  • To let something remain unused or available
  • To let something or someone remain somewhere

reduce

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US / rɪ'dju:s /

UK / rɪˈdus, -ˈdjus /

A2
  • verb
  • To try to decrease, e.g. your weight if overweight
  • To boil a liquid until it has decreased in amount
  • To make something smaller in size, amount, level

where

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US / hwɛə /

UK / hwɛr, wɛr /

A1
  • conjunction
  • At or in the place which
  • In whatever place
  • pronoun
  • Word you use to ask the location of something

another

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US / əˈnʌðə(r) /

UK / əˈnʌðɚ /

A1
  • adjecitve
  • One more, but not this
  • determiner
  • One more added
  • pronoun
  • One more (thing)

ease

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US / i:z /

UK / iz /

A2
  • noun
  • State of being comfortable or relaxed
  • verb
  • To make something less difficult, tight, stressed
  • To move slowly and purposely to get in small space

issue

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US / 'ɪʃu: /

UK / ˈɪʃu /

A2
  • noun
  • Important topic discussed, debated or argued over
  • Single edition of a magazine
  • verb
  • To make something available to be used or sold
  • To deliver a statement, etc. in an official manner

hurt

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US / hɜ:t /

UK / hɚt /

A1
  • noun
  • Mental, emotional, or physical pain
  • verb
  • To cause pain, damage or injury

mental

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US / ˈmentl /

UK / ˈmɛntl /

A2
  • adjecitve
  • Concerning the mind

stabilize

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US / 'steɪbəlaɪz /

UK / ˈstebəˌlaɪz /

B1
  • verb
  • To make stable/consistent, with no major changes

psychiatric

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US / ˌsaɪkiˈætrɪk /

UK / ˌsaɪkiˈætrɪk /

B2
  • adjecitve
  • Concerning the treatment of the mind

beyond

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US / bɪ'jɒnd /

UK / biˈɑnd, bɪˈjɑnd /

A2
  • adverb
  • On or to the farther side
  • In addition to
  • preposition
  • Later in time than
  • Out of the limits of

doctor

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US / ˈdɒktə(r) /

UK / ˈdɑːktɚ /

A1
  • noun
  • Person paid to help people become or stay healthy
  • Person awarded the highest university degree
  • verb
  • To treat someone's illness
  • To change something in order to trick someone

lengthen

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US / 'leŋθən /

UK / ˈlɛŋθən, ˈlɛŋk- /

B1
  • verb
  • To make or become longer in time or distance

keep

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US / ki:p /

UK / kip /

A1
  • noun
  • Large, strong tower in the middle of a castle
  • Money spent on you so you can live in a place
  • verb
  • To continue doing something; not to stop
  • To stop balls going in a goal in sports
  • To not give back or return something
  • (Of food) to not spoil or not rot
  • To take possession of something to own, e.g. a pet
  • To have and continue to hold something
  • To do something that you have promised or agreed
  • To stay in a certain place or condition
  • To maintain the rules

monitor

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US / ˈmɒnɪtə(r) /

UK / ˈmɑ:nɪtə(r) /

A2
  • noun
  • A senior student at school
  • Electronic screen on which you can see images
  • verb
  • To observe and keep a record of something

cancer

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US / 'kænsə(r) /

UK / ˈkænsɚ /

B1
  • noun
  • Any growth caused by abnormal cell division

affect

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US / ə'fekt /

UK / əˈfɛkt /

A2
  • verb
  • To cause a change in something else

mania

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US / ˈmeɪniə /

UK / ˈmeniə,ˈmenjə /

B2
  • noun
  • Mental illness marked by high energy or excitement
  • Extreme interest in, or excitement about

illness

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US / ˈɪlnəs /

UK / ˈɪlnɪs /

A2
  • noun
  • Unhealthy condition of the mind or body

release

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US / rɪ'li:s /

UK / rɪ'li:s /

A2
  • noun
  • Act of freeing someone from a duty or burden
  • Introduction of a new product, film, book, etc.
  • Relief from sadness, suffering or trouble
  • Act of freeing from a jail, cage, prison, etc.
  • verb
  • To free someone from a responsibility or burden
  • To allow a film, music etc. to be sold/distributed
  • To allow to leave a jail, cage, etc.; let out
  • To let go of something you are holding

two

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US / tu: /

UK / tu /

A1
  • number
  • 2

and

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US / ənd /

UK / ənd, ən,ænd /

A1
  • conjunction
  • Used to refer to two or more things
  • Plus; in addition; on top of that
  • Used to introduce an action that follows another

back

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US / bæk /

UK / bæk /

A1
  • adjecitve
  • Farthest from the front e.g. in a classroom
  • adverb
  • Have returned to a place you were before
  • noun
  • The part of a chair that the upper body leans upon
  • Location at the rear of something
  • The reverse of side something
  • Area on the rear of your body
  • verb
  • To bet money on something
  • To go backwards in a car
  • To support and encourage someone or some cause

hope

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US / həʊp /

UK / hop /

A1
  • noun
  • When you wish something will happen; what you wish
  • verb
  • To expect and want something to happen

lot

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US / lɒt /

UK / lɑt /

A1
  • noun
  • What happens to a person in life from chance; fate
  • A group of people seen together
  • Item for sale at an auction
  • Small area of land used for a purpose e.g. parking

suicide

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US / 'su:ɪsaɪd /

UK / ˈsuɪˌsaɪd /

B2
  • noun
  • Act of purposely killing yourself
  • Act that ruins a person's career, status etc.

from

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US / frəm /

UK / frʌm, frɑm,frəm /

A1
  • preposition
  • Starting at a particular place, time or level

gauze

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US / gɔ:z /

UK / ɡɔz /

B2
  • noun
  • Thin cloth that can be seen through

out

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US / aʊt /

UK / aʊt /

A1
  • adverb
  • No longer stylish (e.g. fashion)
  • Away from home, business, or the usual place
  • In a direction/movement away from inside or center
  • noun
  • Act when a batter cannot continue playing
  • verb
  • To tell people a secret

over

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US / 'əʊvə(r) /

UK / ˈovɚ /

A1
  • adverb
  • Finished; no longer happening
  • Towards the ground/away from a standing position
  • noun
  • A set of six consecutive balls bowled in cricket
  • other
  • Finished
  • preposition
  • Showing the relation when a thing is above another
  • On or covering something
  • Above or across something
  • More than you need
  • From one side to the other
  • In the direction of; toward

drink

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US / drɪŋk /

UK / drɪŋk /

A1
  • noun
  • A liquid that you put in your mouth
  • verb
  • To put water in your body through your mouth

ingredient

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US / ɪnˈgri:diənt /

UK / ɪnˈɡridiənt /

B1
  • noun
  • Food item used when making a meal or drink
  • Quality necessary to be something to work well

most

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US / məʊst /

UK / most /

A1
  • adverb
  • Very; extremely
  • Greatest possible degree
  • pronoun
  • Nearly all of something

bandage

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US / ˈbændɪdʒ /

UK / ˈbændɪdʒ /

B1
  • noun
  • Cloth or wrapping used to cover a wound
  • verb
  • To cloth or wrapping used to cover a wound

can

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US / kæn /

UK / kən,kæn /

A1
  • noun
  • A metal container for storing food
  • other
  • Able to; have the skill to; have the time to
  • verb
  • To have permission to
  • To be possible to do
  • To preserve food by sealing it in a metal container

effect

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US / ɪ'fekt /

UK / ɪˈfɛkt /

A1
  • noun
  • An advantage, benefit
  • Change brought about by a cause; result

perception

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US / pəˈsepʃn /

UK / pɚˈsɛpʃən /

B1
  • noun
  • Way in which one sees or understands something

wound

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US / waʊnd /

UK / waʊnd /

A2
  • noun
  • Sadness or displeasure caused by a bad memory
  • Physical injury, especially that suffered in war
  • verb
  • To rotate a part of say a watch to make it work
  • To hurt someone emotionally
  • To injure someone in a fight with a knife gun etc.

autopilot

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US / ˈɔ:təʊpaɪlət /

UK / ˈɔ:toʊpaɪlət /

C2
  • noun
  • (For ships, planes) automatic navigational device

reversible

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US / rɪ'vɜ:səbl /

UK / rɪˈvɚsəbəl /

B1
  • adjecitve
  • Able to be reversed
  • (Of clothes) able to be worn inside out

sew

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US / səʊ /

UK / so /

B1
  • verb
  • To make something using a needle and thread

testing

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US / ˈtestɪŋ /

UK / ˈtestɪŋ /

A1
  • verb
  • To be given a medical examination
  • To try to establish the truth or nature of
  • To ask a series of questions to measure knowledge

thin

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US / θɪn /

UK / θɪn /

A1
  • adjecitve
  • Flowing with ease; with a high percentage of water
  • (Of air) having little oxygen
  • Being or growing far apart in small amounts
  • Not thick; not wide in size
  • Having little flesh or fat on the body
  • Being weak or useless
  • verb
  • To make flow more easily by adding water or liquid

usually

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US / ˈju:ʒuəli /

UK / ˈjuːʒuəli /

A1
  • adverb
  • Normally; regularly

video

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US / 'vɪdɪəʊ /

UK / ˈvɪdiˌo /

A2
  • adjecitve
  • Of a moving film, with sound
  • noun
  • Recording capturing action with sound
  • verb
  • To make a moving film of, with sound

want

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US / wɔnt /

UK / wɑnt, wɔnt /

A1
  • noun
  • Something you desire or wish for
  • State or condition of poverty
  • verb
  • To desire or wish for something; hope for a thing

yet

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US / jet /

UK / jɛt /

A1
  • adverb
  • At a later time (used after ‘not’)
  • (Used to emphasize that thing is, will be greater)
  • Eventually; at a future time
  • Until now; up to the present
  • conjunction
  • Adding to what has been said, often as a contrast

weight

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US / weɪt /

UK / wet /

A2
  • noun
  • How heavy something is
  • Metal object to measure how heavy something is
  • Importance, power, and influence person, thing has
  • A source of worry, sadness, or emotional stress

not

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US / nɒt /

UK / nɑt /

A1
  • adverb
  • Word indicating the negative
  • (Used to form the negative of verbs)

our

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US / 'aʊə(r) /

UK / aʊr /

A1
  • determiner
  • Belonging to us

maybe

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US / ˈmeɪbi /

UK / ˈmebi /

A1
  • adverb
  • Possibly but not certainly; perhaps

quite

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US / kwaɪt /

UK / kwaɪt /

A1
  • adverb
  • Not very; fairly
  • Very; In a complete or total manner

compare

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US / kəm'peə(r) /

UK / kəmˈpɛr /

A1
  • verb
  • To consider how similar and different things are

study

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US / 'stʌdɪ /

UK / ˈstʌdi /

A1
  • noun
  • Room that a person studies or reads in
  • Piece of research
  • Topic or subject you research or learn about
  • verb
  • To focus on learning something usually at school

stomach

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US / 'stʌmək /

UK / ˈstʌmək /

A2
  • noun
  • Place in the body where food is processed
  • verb
  • to be able to accept something unpleasant

would

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US / wʊd /

UK / wʊd /

A1
  • other
  • Used to indicate something imagined
  • Used to ask or request something politely
  • Verb used to indicate possibility, request etc.
  • Used to indicate a preference
  • Used to indicate a reaction
  • Indicates something that occurred repeatedly
  • Used to indicate willingness or ability to do

ability

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US / ə'bɪlətɪ /

UK / əˈbɪlɪti /

A2
  • noun
  • The power, resources or skill to do something

but

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US / bət /

UK / bʌt,bət /

A1
  • conjunction
  • Used before you say something different, opposite

especially

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US / ɪˈspeʃəli /

UK / ɛˈspɛʃəli, ɪˈspɛʃ- /

A1
  • adverb
  • More than usual; extremely

give

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US / ɡɪv /

UK / ɡɪv /

A1
  • noun
  • Degree of flexibility in something, a material
  • verb
  • To hand over or present something to someone
  • To cause someone to have or experience something

good

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US / ɡʊd /

UK / ɡʊd /

A1
  • adjecitve
  • Proper, appropriate or right
  • (Of an amount) enough; plenty
  • Excellent; high quality
  • Acting well or properly; of moral character
  • In a positive or happy emotional state
  • noun
  • Advantage or benefit

generally

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US / /

UK / /

A2
  • adverb
  • Usually; as a rule; by, to or for most people

ion

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US / 'aɪən /

UK / ˈaɪən /

B2
  • noun
  • Atoms with either a positive or negative charge

now

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US / naʊ /

UK / naʊ /

A1
  • adverb
  • At the present time or moment
  • Right away or in the next possible moment
  • Used to refer to something that just happened
  • Time between the present and a moment in the past
  • conjunction
  • Resulting from or because of something

organ

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US / 'ɔ:ɡən /

UK / ˈɔrɡən /

B1
  • noun
  • Part of a person's body with a particular function
  • Large institution or body
  • Large wind instrument similar to a piano

measure

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US / ˈmeʒə(r) /

UK / ˈmɛʒɚ /

A1
  • noun
  • Plan to achieve a desired result
  • Tool used to calculate the size of something
  • verb
  • To determine the value or importance of something
  • To calculate size, weight or temperature of

table

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US / ˈteɪbl /

UK / ˈtebəl /

A1
  • noun
  • Diagram that shows data in rows and columns
  • Raised flat surface you sit at to work or eat
  • verb
  • To leave an idea to be discussed at a later date

schedule

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US / ˈʃedju:l /

UK / ˈskedʒu:l /

A2
  • noun
  • A list of events and their times
  • A plan to do something at a certain time
  • verb
  • To plan to do something at a certain time

address

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US / ə'dres /

UK / əˈdrɛs /

A1
  • noun
  • Exact street location of a place
  • A formal speech to a group of people
  • verb
  • To write the place someone lives on a letter
  • To refer to someone or something formally
  • To make a formal speech to a group of people
  • To try to find a solution to; think about

become

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US / bɪ'kʌm /

UK / bɪˈkʌm /

A1
  • verb
  • To begin to be; grow to be; develop into
  • To be suitable for a particular job or role

fda

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US / ˌef diː ˈeɪ /

UK / ˌef diː ˈeɪ /

A1
  • abbreviation
  • FDA is an acronym

hero

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US / ˈhɪərəʊ /

UK / ˈhɪroʊ /

A2
  • noun
  • Person of great courage/strength who saves others
  • Main male character in a book, play or story

mood

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US / mu:d /

UK / mud /

A1
  • noun
  • Emotion or a state of mind; how you feel

slow

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US / sləʊ /

UK / sloʊ /

A1
  • adjecitve
  • Lacking activity, busyness or excitement
  • (Clock) showing time earlier than the actual time
  • Having difficulty understanding simple things
  • Moving or happening without speed; not fast
  • verb
  • To move, with less speed than before
  • To move or go without much speed

content

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US / 'kɒntent /

UK / ˈkɑnˌtɛnt /

A2
  • adjecitve
  • Being happy or satisfied
  • noun
  • Information in something, e.g. book or computer

exert

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US / ɪgˈzɜ:t /

UK / ɪgˈzɜ:rt /

B2
  • verb
  • To make something have an effect on something else

recent

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US / 'ri:snt /

UK / ˈrisənt /

A1
  • adjecitve
  • Happening or beginning not long ago

ship

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US / ʃɪp /

UK / ʃɪp /

A1
  • noun
  • Large boat
  • verb
  • To transport goods by boat, truck or plane
  • Subtitles section
  • A game changer in the late 1940s, lithium revolutionized the treatment of bipolar disorder, offering a beacon of hope for millions of people.
  • Yet, as decades rolled on, this miracle compound was gradually nudged off its pedestal, replaced by newer shiny contenders, the second generation antipsychotics.
  • Why did lithium, once the gold standard, get pushed off into the shadows?
  • Is it time for us to reevaluate the value of this underappreciated hero?
  • That's what I'm talking about today.
  • I'm Dr. Tracey Marks, a psychiatrist, and I make mental health education videos.
  • Lithium has been an essential treatment for bipolar disorder for more than half a century.
  • The mineral lithium was discovered in the late 1800s, but Australian psychiatrist John Cade discovered it as a treatment for bipolar disorder in the late 1940s.
  • It was effective in managing manic and depressive episodes and reducing the risk of suicide.
  • For decades, lithium remained the gold standard in the treatment of bipolar disorder.
  • Then over the years, lithium usage in the United States started to wane with the rise of the second generation antipsychotics.
  • These drugs, including olanzapine, quetiapine, risperidone, and others, came onto the scene in the 1990s.
  • They promised to be better tolerated with less side effects compared to the older antipsychotic medications like Haldol, and psychiatrists started using them more.
  • Why?
  • Several factors.
  • One is the ease of use.
  • Lithium requires monitoring your blood levels.
  • It has a narrow therapeutic window, which means that the range between the dose of the drug that is effective or works to treat your symptoms and the dose that could be harmful or toxic is quite small.
  • So there's a thin line between the dose that can help and the dose that can hurt.
  • This makes dosing and monitoring lithium very important.
  • You can't just take lithium on autopilot and never check to see how much of it is in your blood.
  • The concentration of lithium in your blood that works for most people is between 0.6 and 1.2 milliequivalents per liter.
  • Here's a useful table for lithium levels.
  • 0.1 to 0.4 is a low level for preventative health.
  • And here's a small aside about preventative health.
  • Some people believe a little bit of lithium is good for overall health.
  • In fact, one of the key ingredients in the drink 7-Up, which is now made by PepsiCo, was lithium citrate.
  • The FDA made the company, which was not Pepsi at the time, remove lithium from the drink in 1948.
  • But back to the table.
  • 0.4 to 0.8 is a medium level that treats depression and some mood instability.
  • 0.8 to 1.2 is a high level that treats mania.
  • And then greater than 1.2 is a toxic level.
  • Signs of toxicity are confusion, nausea, and maybe even vomiting, diarrhea, blurred vision, and severe tremor.
  • As a non-toxic side effect, lithium can cause a mild tremor that doesn't interfere with your ability to do things.
  • But the toxicity tremor is more prominent and may make it difficult for you to do things like hold a cup in your hand without spilling the contents.
  • So when you take lithium, you have to be careful about staying hydrated.
  • If you have any big shifts in your fluid balance, like from vomiting or diarrhea or heavy sweating, you have to look out for signs of toxicity.
  • But toxicity issue aside, you do have to get regular blood tests, like every time your dose changes.
  • Then you can move it out to every three months, then every six months, and then annually.
  • For some people, it's hard enough to remember to take a pill every day, but then needing to go to the lab regularly is just too much of a hassle.
  • A second factor that has made lithium become less popular is some of the side effects that affect your organs long-term.
  • The two main organs are your thyroid and your kidney.
  • Lithium can interfere with the production and release of thyroid hormones.
  • If this happens, you can become hypothyroid, which can look like tiredness, depression, weight gain, cold intolerance, and a slow heart rate.
  • Lithium can also cause inflammation of your thyroid gland.
  • A 2023 study by Joseph and colleagues found that a third of people in their study on long-term lithium treatment developed thyroid disorder.
  • In this study, the average time on lithium was eight years.
  • As for your kidney, lithium is metabolized by your kidneys and can interfere with the way your kidneys concentrate urine.
  • You may notice that you have to urinate more frequently.
  • If you take lithium for a long time, usually years, you can develop nephrogenic diabetes insipidus, where the kidneys are no longer able to concentrate urine effectively.
  • This issue is reversible if you stop it soon after you notice these symptoms.
  • Also, the good news is taking lithium all at once at bedtime reduces this problem and is safer on the kidneys.
  • So because of these potential effects on your organs from long-term use, it's important that in addition to blood level testing, you also get regular blood tests to monitor your kidney and your thyroid function.
  • The last reason that I'll discuss on why we shifted away from lithium is the perception that the antipsychotics work faster and better.
  • It is true that lithium takes longer to see an effect.
  • It's generally thought that you need to give it a month, and that's once you get to a dose that's in the therapeutic range.
  • Lithium can cause nausea when you first start, and this is why people will start off with split dosing, like half the dose in the morning and half in the evening.
  • Then once your stomach gets used to it, you can switch to taking it all at night for the sake of your kidneys.
  • Every time you change the dose, you need to get blood work to check your new level.
  • You have to wait a week after you change the dose to get the blood work.
  • Generally, a 300 milligram capsule measures out to about a blood level of 0.25.
  • This is a rough estimate as everyone's metabolism is different.
  • So let's say your doctor starts you out with 600 milligrams of lithium, and then you get blood work.
  • Your level may be roughly around 0.5, which is in the low range and not considered high enough for mania.
  • So then your doctor will add more lithium and have you get your level checked again.
  • So you can see where I'm going here.
  • This can get tedious.
  • And if you're manic and in the process of clearing out your bank account to build a rocket ship or making plans to sleep with your boss's spouse, you don't wanna wait four to six weeks for the lithium to take effect.
  • On the other hand, a good dose of olanzapine, risperidone or aripiprazole is like spraying water on that fire and extinguishing it in a matter of days.
  • Generally speaking, the antipsychotics can exert their effects within days to a week.
  • All of your symptoms may not be gone in that short period, but you can usually see, at least feel a little more stable.
  • Also with the antipsychotics, you don't need to monitor blood levels.
  • So with all this said, why should we reconsider using lithium as the first treatment choice for bipolar disorder?
  • Several reasons.
  • Unlike antipsychotics, lithium actually addresses one of the root causes of bipolar disorder.
  • Recent studies have shown that people with bipolar disorder have increased sodium and calcium in their cells due to altered ion transport mechanism.
  • Lithium actually corrects this by blocking sodium entry into the cells so that the level is normalized.
  • So it corrects the problem at the cell level.
  • Changing how your cells work changes everything they do downstream.
  • So lithium corrects the source and antipsychotics work at the downstream level affecting the chemicals that the cells produce.
  • An analogy would be, if you have a bleeding wound, lithium sews up the wound and the antipsychotics are the gauze and bandaging that keeps the wound from seeping.
  • Lithium is one of the few drugs that is specifically anti-suicidal.
  • Ketamine is the other juggernaut in that department.
  • Lithium also stabilizes your body clock by changing the way your circadian genes work.
  • It works at the genetic level.
  • Your body clock affects a lot of body systems, but the most noticeable are sleep and energy level.
  • People with bipolar disorder are often night owls and if left to their own devices can end up with a flip sleep schedule of sleeping during the day and being awake all night.
  • It can be a struggle to stay on a night sleeping schedule.
  • Lithium's effects go beyond psychiatric.
  • Going back to its effect on cells, lithium has anti-aging properties because of how it affects telomeres.
  • Telomeres are the protective caps on the ends of our chromosomes, somewhat like the plastic tips on shoelaces.
  • Each time a cell divides, the telomeres get a bit shorter and when they get too short, the cell can no longer divide and becomes inactive or dies.
  • The shortening process is associated with aging, cancer and other medical disorders.
  • Researchers have seen that people with bipolar disorder taking lithium had longer telomeres than people with and without bipolar disorder who had not taken lithium.
  • So the conclusion here is that lithium lengthens telomeres.
  • Another thing lithium does is it improves brain health by reducing brain shrinkage.
  • Antidepressants also do this, but lithium does it more.
  • Lastly, although lithium does have side effects that include cognitive slowing and loss of creativity, it does not cause the weight gain and metabolic issues that the antipsychotics do.
  • You can gain weight, but not as much as with the antipsychotics.
  • Since lithium can make you thirsty, you have to be careful not to quench your thirst with sugary drinks or even diet sodas, which can still lead to weight gain.
  • The antipsychotic medications tend to make you crave carbs and not feel full, but with lithium, you can end up drinking your calories.
  • So there's a pretty strong argument for revisiting lithium if you have bipolar disorder and especially if you are newly diagnosed.
  • Lithium is particularly good at keeping episodes away at the beginning of your illness, but lithium isn't good for everyone.
  • It doesn't work as well on people with mixed episodes or substance use disorder.
  • For more on this topic, check out this video on classic versus atypical bipolar disorder, and this other one on managing the metabolic effects of antipsychotic medications.
  • Thanks for watching.
  • See you next time.