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What's missing in medical research? - Greg Foot

Video vocabulary

clot

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US / klɒt /

UK / klɑ:t /

B2
  • noun
  • Mass of blood, etc. that has dried up/become thick
  • verb
  • To make a liquid such as blood turn thick or solid

effective

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US / ɪˈfektɪv /

UK / ɪˈfɛktɪv /

A1
  • adjecitve
  • Working efficiently to produce a desired result

genetic

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US / dʒəˈnetɪk /

UK / dʒəˈnɛtɪk /

B1
  • adjecitve
  • Of, relating to, or controlled by genes

half

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US / hɑ:f /

UK / hæf, hɑf /

A1
  • adjecitve
  • Not complete
  • adverb
  • Partly; somewhat
  • noun
  • One of two equal periods of game time in a sport
  • The part you get when one is divided into two;

instruction

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US / ɪn'strʌkʃn /

UK / ɪnˈstrʌkʃən /

A2
  • noun
  • A command for someone formally to do something
  • Act of teaching or explaining to others
  • Information about how to do or use something

big

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US / bɪɡ /

UK / bɪɡ /

A1
  • adjecitve
  • Popular
  • Serious
  • Large

little

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US / 'lɪtl /

UK / ˈlɪtl /

A1
  • adjecitve
  • Being short in length of time
  • Not great in size, amount, or degree; small
  • Being very young or younger than others
  • adverb
  • By an amount or degree that is not very much
  • Not often; rarely
  • noun
  • A person's name

let

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US / let /

UK / lɛt /

A1
  • verb
  • To allow someone to do something
  • Introducing a suggestion to do something together
  • To rent a house, etc. to others

might

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US / maɪt /

UK / maɪt /

A1
  • other
  • Used to politely request an action
  • Used to express that something could happen
  • Power, strength, force or influence

researcher

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US / rɪ'sɜ:tʃə(r) /

UK / rɪˈsətʃɚ /

A2
  • noun
  • Someone who works to find new facts and ideas

the

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US / ðə /

UK / ðə /

A1
  • article
  • Used to refer to something already mentioned
  • Used to show there is only one of something
  • determiner
  • Used to describe all of a family

vary

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US / ˈveəri /

UK / ˈveri /

A2
  • verb
  • To change something and make it different
  • To be changeable, both up and down

across

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US / əˈkrɔs /

UK / əˈkrɔs,əˈkrɑs /

A1
  • adverb
  • Distance from one side to another
  • (Go) from one side to the other of something

may

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US / meɪ /

UK / me /

A1
  • noun
  • 5th month of the year
  • other
  • Used to express a desire
  • Expresses permission, possibility or probability
  • Used to show that a thing could be true

this

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US / ðɪs /

UK / ðɪs /

A1
  • adjecitve
  • Used to indicate something already been discussed
  • Used to indicate something happening around now
  • adverb
  • An indication by a physical motion or gesture
  • A specific amount of
  • determiner
  • Person, thing, or idea near you
  • pronoun
  • Person, thing that has already been discussed

differently

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US / 'dɪfrəntlɪ /

UK / ˈdɪfərəntlɪ /

A2
  • adverb
  • In another and different manner

solution

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US / səˈlu:ʃn /

UK / səˈluʃən /

A2
  • noun
  • Mix of a liquid and a solid or a gas
  • Way to solve or deal with a problem

also

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US / 'ɔ:lsəʊ /

UK / ˈɔlso /

A1
  • adverb
  • In addition; too; in a similar way

identify

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US / aɪ'dentɪfaɪ /

UK / aɪˈdɛntəˌfaɪ /

B1
  • verb
  • To indicate who or what someone or something is

kind

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US / kaɪnd /

UK / kaɪnd /

A1
  • adjecitve
  • In a caring and helpful manner
  • friendly and considerate
  • noun
  • One type of thing

how

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US / haʊ /

UK / haʊ /

A1
  • adjecitve
  • To what degree? in what amount?
  • adverb
  • (Used to explain the way to do something)
  • exclamation
  • For what purpose or reason?
  • (Used to ask someone or something's condition)

mutation

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US / mju:'teɪʃn /

UK / mjuˈteʃən /

B2
  • noun
  • Change that changes genetic structure

year

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US / jə: /

UK / jɪr /

A1
  • noun
  • Unit of time equal to 12 months or 365 or 366 days
  • Used to refer to the age of a person

you

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US / jʊ /

UK / ju /

A1
  • pronoun
  • Person someone is speaking or writing to
  • Person or people in general

descent

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US / dɪˈsent /

UK / dɪˈsɛnt /

B1
  • noun
  • Movement downward; movement toward something bad
  • The origin of your family; your family before you

into

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US / 'ɪntə /

UK / ˈɪntu /

A1
  • preposition
  • Moving or going inside something
  • In the same direction as; in the direction of
  • So as to become; taking the state of

one

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US / wʌn /

UK / wʌn /

A1
  • pronoun
  • You; we; people in general; someone
  • The thing or person previously referred to
  • adjecitve
  • Used to refer to people generally
  • Being a strong example of (something mentioned)
  • number
  • Number 1

other

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US / 'ʌðə(r) /

UK / ˈʌðər /

A1
  • adjecitve
  • A thing different from that mentioned
  • determiner
  • (Something) else; not the first (one)
  • pronoun
  • Being the one and only thing of that category

settle

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US / 'setl /

UK / ˈsɛtl /

A2
  • noun
  • Type of wooden seat
  • verb
  • To make (a child, etc.) feel calm/ready for sleep
  • To complete or finalize e.g. a contract or debt
  • To end some troubles by reaching an agreement
  • To become accustomed to a new environment
  • (Of liquids) to move to the bottom of a container

than

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US / ðən /

UK / ðən /

A1
  • conjunction
  • Used to compare two things that are not equal

turn

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US / tɜ:n /

UK / tɚn /

A1
  • noun
  • Place where changing of direction happens
  • Your time or chance to perform a duty
  • Your chance to play or do in say a game
  • Unexpected change, as in the weather
  • verb
  • To become (a particular age)
  • To become a different quality, color, etc.
  • To change the direction of something, e.g. a car
  • To move in an opposite direction or position
  • To shape metal with a spinning tool

order

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US / 'ɔ:də(r) /

UK / ˈɔrdɚ /

A1
  • noun
  • Religious or social group, as of nuns
  • Instructions to others to do what you want
  • State in which things are neat and organized
  • What you ask to buy, e.g. food in restaurant
  • Social or political control of an area
  • verb
  • To put things in a sequence, e.g. a, b, c
  • To give instructions to others to do what you want
  • To ask for something you want to buy, e.g. a meal

run

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US / rʌn /

UK / rʌn /

A1
  • noun
  • Journey between two places made by ship or car
  • Series of similar things or successes and failures
  • Act of running; exercise of running
  • verb
  • To depart or travel according to a schedule
  • To cause an animal to move in a certain direction
  • (Of an engine) to be operating
  • To start or use a computer program
  • To flow in a certain direction, like a liquid
  • To manage or operate a business
  • To operate or drive something
  • (Of a road) to go from one place to another
  • To move your legs faster than walking

treat

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US / tri:t /

UK / trit /

A1
  • noun
  • Something you buy for others as a surprise present
  • something that tastes good and that is not eaten often
  • verb
  • To pay for the food or enjoyment of someone else
  • To use medical methods to try to cure an illness
  • To act in a certain way toward someone

absolutely

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US / ˈæbsəlu:tli /

UK / ˈæbsəˌlutli, ˌæbsəˈlutli /

A2
  • adverb
  • Completely; totally; very

expand

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US / ɪk'spænd /

UK / ɪkˈspænd /

A2
  • verb
  • To make something larger in size, number, amount

find

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US / faɪnd /

UK / faɪnd /

A1
  • noun
  • Object discovered by chance
  • Things that have been discovered from searching
  • verb
  • To become aware of something that is happening
  • To discover or meet by chance
  • To decide if someone is guilty of a crime, or not
  • To learn through study, research, or effort
  • To discover something by looking for it

mean

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US / mi:n /

UK / min /

A1
  • adjecitve
  • Being good at
  • Nasty; unkind
  • Not liking to spend money; cheap; stingy
  • noun
  • Average of a set of numbers
  • verb
  • To express a particular idea or thought
  • To intend to do something in particular
  • To have a particular meaning or value

variation

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US / ˌveəriˈeɪʃn /

UK / ˌvɛriˈeʃən, ˈvær- /

A2
  • noun
  • Something almost the same as another but different
  • Music played with a different tune from another

dose

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US / dəʊs /

UK / doʊs /

B1
  • noun
  • An amount of medicine to be taken at any one time
  • verb
  • To give a certain amount of something to someone

nothing

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US / 'nʌθɪŋ /

UK / ˈnʌθɪŋ /

A1
  • noun
  • Item of little or no value, importance, interest
  • Number or value of zero
  • pronoun
  • Not anything, not a single thing

tell

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US / tel /

UK / tɛl /

A1
  • verb
  • To (strongly) advise a person to do something
  • To be able to guess
  • To say or communicate information to someone
  • To inform, but without speaking; indicate
  • To have a negative effect on someone
  • To order someone to do something; command
  • To recognize something based on certain signs
  • To report something to an authority
  • To explain something or teach someone something

tissue

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US / ˈtɪʃu: /

UK / ˈtɪʃu /

A2
  • noun
  • Substance formed by cells of living thing; flesh
  • Kind of thin, light paper used to pack objects
  • Thin soft paper for blowing the nose, etc.

get

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US / ɡet /

UK / ɡɛt /

A1
  • verb
  • To become affected by illness or disease
  • To begin to feel or understand an emotion or idea
  • To send or bring someone or something home, etc.
  • To go somewhere to obtain something
  • To (cause to) do a particular thing
  • To obtain, receive or be given something
  • To currently have
  • To prepare for use
  • To understand something being said or read

hard

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US / hɑ:d /

UK / hɑː(r)d /

A1
  • adjecitve
  • Difficult to do; difficult to understand
  • (Of facts) not able to be misunderstood; clear
  • (Of alcohol) strong
  • Involving or requiring lots of work, effort, care
  • Being full of pain, trouble, and problems
  • Strong
  • (Of edge) clear; sharp
  • Difficult to bend, break or cut; solid
  • adverb
  • With lots of force, power, or impact

include

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US / ɪnˈklu:d /

UK / ɪnˈklud /

A1
  • verb
  • To make someone, something part of a group

search

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US / sɜ:tʃ /

UK / sɜ:rtʃ /

A2
  • noun
  • Examination of person to find something
  • Action to find an answer to a problem
  • Action of trying to find someone or something
  • verb
  • To examine a person's clothing to find something
  • To look for an answer or explanation to a problem
  • To look carefully for someone or something

then

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US / ðen /

UK / ðɛn /

A1
  • adverb
  • A time that is not now
  • Following another thing in time or arrangement
  • Following on reasonably from what was just stated
  • At that time, not now

about

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US / ə'baʊt /

UK / əˈbaʊt /

A1
  • adverb
  • To be ready to; going to
  • Nearly; approximately; roughly
  • Near; next to; close to
  • In every direction; in the area of
  • preposition
  • Concerning or of (a topic)

different

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US / ˈdɪfrənt /

UK / ˈdɪfrənt /

A1
  • adjecitve
  • Not of the same kind; unlike other things

even

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US / 'i:vn /

UK / ˈivən /

A1
  • adjecitve
  • Being equal in influence, power, possibility etc.
  • Being divided equally or fairly
  • (Of teams/contest) with similar chances of success
  • Smooth, level, or regular
  • Can be divided by 2; ending in 2, 4, 6, 8, or 0
  • At a regular, equally steady manner
  • Remaining steady and unchanging
  • adverb
  • (When this is surprising) as well; too
  • (Used to compare two things/stress the difference)
  • verb
  • To make something level; to flatten
  • To make something equal

people

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US / 'pi:pl /

UK / ˈpipəl /

A1
  • noun
  • Persons sharing culture, country, background, etc.
  • Men, Women, Children

that

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US / ðæt /

UK / ðæt, ðət /

A1
  • adjecitve
  • The person or thing being talked about
  • Used to identify something both the speakers know
  • adverb
  • Used to reinforce adjectives and adverbs
  • To such a degree
  • conjunction
  • Used to connect a noun clause
  • Used to introduce an adverbial clause
  • Used to introduce a noun clause
  • determiner
  • Used as a noun to refer to something
  • pronoun
  • Referring an object far away
  • Used to refer to the relative pronoun ‘which’

storey

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US / 'stɔ:rɪ /

UK / ˈstɔri, ˈstori /

B1
  • noun
  • One of many floors or levels in a building

what

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US / wɒt /

UK / hwɑt, hwʌt, wɔt, wʌt,hwət, wət /

A1
  • pronoun
  • Thing or things that; the same kind as
  • Used to emphasize something you are about to say
  • adjecitve
  • Used to refer to a particular amount, or number
  • Used to place emphasis on a particular quality
  • adverb
  • To a certain degree
  • determiner
  • Question words used for asking for information
  • exclamation
  • Used to express excitement, shock, or surprise
  • Used to ask people to repeat something they said

cause

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US / kɔ:z /

UK / kɔz /

A2
  • noun
  • Belief, goal or organization that people support
  • Reason for
  • verb
  • To make something happen; create effect or result

mainly

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US / ˈmeɪnli /

UK / ˈmenli /

A2
  • adverb
  • Mostly; usually; being the largest part

phase

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US / feɪz /

UK / fez /

A2
  • noun
  • Different stages of the moon from new to full
  • Distinct part or step in a process
  • One stage of a process or series of stages
  • verb
  • To make happen in a gradual ordered way

everywhere

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US / ˈevriweə(r) /

UK / ˈevriwer /

A1
  • adverb
  • Every place

empire

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US / ˈempaɪə(r) /

UK / ˈɛmˌpaɪr /

B1
  • noun
  • Group of countries controlled by one government

right

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US / raɪt /

UK / raɪt /

A1
  • adjecitve
  • Correct or true
  • The south side of you looking at the rising sun
  • adverb
  • Exactly in a place or time
  • Being appropriate for a particular event
  • In a straight or direct manner
  • noun
  • Something you are legally or morally allowed to do
  • Ideal of what is just and good
  • Political view based on conservatism
  • verb
  • To fix something previously wrong or unjust
  • To make upright, as a boat that has turned over

she

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US / ʃɪ /

UK / ʃi /

A1
  • pronoun
  • Female person or animal mentioned before
  • (Refers to female person mentioned before)

bias

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US / 'baɪəs /

UK / ˈbaɪəs /

B1
  • noun
  • Preference to believe things even if incorrect
  • verb
  • To unfairly favor one view over another

cell

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US / sel /

UK / sɛl /

A2
  • noun
  • Smallest unit of living things in biology
  • Group of people - often from a secret organization
  • Prisoner's room in a jail
  • Shortened form of 'cellphone'

diversity

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US / daɪ'vɜ:sətɪ /

UK / dɪˈvə:sɪti, daɪ- /

B1
  • noun
  • Having a range of different races, ideas etc.

each

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US / i:tʃ /

UK / itʃ /

A1
  • determiner
  • Every one of two or more things
  • pronoun
  • Per one person or thing

difference

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US / 'dɪfrəns /

UK / ˈdɪfərəns, ˈdɪfrəns /

A1
  • noun
  • A thing or issue that people do not agree about
  • Not of the same kind; unlike other things

biomarker

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US / 'baɪɒmɑ:kər /

UK / 'baɪɒmɑ:kər /

A1
  • noun

news

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US / nju:z /

UK / nu:z /

A1
  • noun
  • Broadcast on radio or TV about recent events
  • Information about recent events

begin

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US / bɪ'ɡɪn /

UK / ˈbeɡɪn /

A1
  • verb
  • To do the first part of an action; to start

notable

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US / ˈnəʊtəbl /

UK / ˈnoʊtəbl /

A2
  • adjecitve
  • Being famous or well-known
  • Deserving notice or mention; important

test

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US / test /

UK / test /

A1
  • noun
  • A medical examination
  • Action to establish the truth or nature of
  • Examination; questions to measure knowledge
  • verb
  • To be given a medical examination
  • To try to establish the truth or nature of
  • To ask a series of questions to measure knowledge

unique

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US / jʊ'ni:k /

UK / juˈnik /

A2
  • adjecitve
  • Unlike other things; being the only one like it

well

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US / wel /

UK / wɛl /

A1
  • adjecitve
  • Being in a fortunate, good condition or state
  • Healthy and in good condition
  • adverb
  • In an acceptable, proper, or successful manner
  • In a complete, total, or full manner
  • A great and considerable degree
  • In a successful way, in a good or satisfactory way
  • exclamation
  • Used to begin or continue a particular statement
  • Used to show you want to start saying something
  • Used to express that you are waiting for a reply
  • You say this to change the topic of a conversation
  • Used to indicate you are making a final remark
  • noun
  • Long deep hole in the ground to get water
  • verb
  • To cause your eyes to fill with tears

volunteer

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US / ˌvɒlən'tɪə(r) /

UK / ˌvɑlənˈtɪr /

B2
  • adjecitve
  • Working willingly without pay to help others
  • noun
  • Person who helps others without being paid
  • verb
  • To work willingly without pay to help others

for

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US / fə(r) /

UK / fɔr,fə /

A1
  • preposition
  • Used to show the purpose, or need of something

through

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US / θru: /

UK / θru /

A2
  • adjecitve
  • having finished using or doing something
  • adverb
  • From the beginning of something until the end
  • preposition
  • Over, in, across an entire thing or place
  • Allowing you to pass between, or to
  • By a particular way or process; by the use of

time

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US / taɪm /

UK / taɪm /

A1
  • noun
  • Speed at which music is played; tempo
  • Point as shown on a clock, e.g. 3 p.m
  • Number of hours, minutes needed to do something
  • Occasion when something happens
  • Period or occasion that something occurred
  • Period in history or the past
  • Something measured in minutes, hours, days, etc.
  • How long an event takes; duration
  • verb
  • To check speed at which music is performed
  • To choose a specific moment to do something
  • To measure how long an event takes, e.g. a race
  • To schedule something to occur at a specific moment

evolve

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US / ɪ'vɒlv /

UK / ɪˈvɑlv /

B1
  • verb
  • To develop certain features
  • To develop or change slowly over time
  • To slowly change or develop into something better

range

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US / reɪndʒ /

UK / rendʒ /

A2
  • noun
  • Cooking stove with multiple burners
  • Given distance from a point; how far plane can fly
  • Large grassy area where cattle wander and feed
  • Group or chain of mountains
  • Set of things with something in common
  • Limits within which something extends or varies
  • A set of products, e.g. so that people can choose
  • verb
  • To cover an area from one point to another
  • To extend to or vary within given limits
  • To put things in a row or in line
  • To wander or explore

light

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US / laɪt /

UK / laɪt /

A1
  • adjecitve
  • Being bright making it easy to see; not dark
  • Being pale and lacking darkness of color
  • Not heavy; weighing only a little
  • adverb
  • Carrying few bags when traveling
  • noun
  • A source of energy that makes a room or area bright
  • Way in which something or someone is understood
  • verb
  • To cause something to burn; put a burning match to
  • To provide a way to see ahead

possibly

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US / ˈpɒsəbli /

UK / ˈpɑ:səbli /

A1
  • adverb
  • May be true or likely, but is uncertain

those

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US / ðəʊz /

UK / ðoz /

A1
  • determiner
  • The people or things we are talking about
  • pronoun
  • The objects far from the speaker

couple

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US / 'kʌpl /

UK / ˈkʌpəl /

A2
  • noun
  • Two people in a romantic relationship
  • Two of something; two people; a pair
  • verb
  • To join something to something else
  • (Two animals) to engage in sexual relations
  • To put two people or things together

something

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US / ˈsʌmθɪŋ /

UK / ˈsʌmθɪŋ /

A1
  • adverb
  • In some degree or measure
  • noun
  • a person or thing of some value or consequence
  • pronoun
  • Thing that is not yet known or named
  • Approximately

leave

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US / li:v /

UK / liv /

A1
  • noun
  • Permission to do something
  • Vacation time; time off work
  • verb
  • To go away from; depart
  • To gift property to someone after you die
  • To allow something to continue happening
  • To let something remain unused or available
  • To let something or someone remain somewhere

where

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US / hwɛə /

UK / hwɛr, wɛr /

A1
  • conjunction
  • At or in the place which
  • In whatever place
  • pronoun
  • Word you use to ask the location of something

ward

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US / wɔ:d /

UK / wɔ:rd /

B1
  • noun
  • Person's name
  • Child legally protected and cared for by a court
  • Section or part of a town or city
  • Separate part or area of a hospital

any

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US / 'enɪ /

UK / ˈɛni /

A1
  • adjecitve
  • One, or some, no matter which
  • pronoun
  • One (thing) of many; some

particular

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US / pəˈtɪkjələ(r) /

UK / pɚˈtɪkjəlɚ, pəˈtɪk- /

B2
  • adjecitve
  • One specific (one)
  • Having firm ideas about what is desirable
  • Being special or more than is typical

relevant

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US / ˈreləvənt /

UK / ˈrɛləvənt /

A2
  • adjecitve
  • Having an effect on an issue; related or current

think

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US / θɪŋk /

UK / θɪŋk /

A1
  • verb
  • To have an idea about something without certainty
  • To have an idea, opinion or belief about something

arise

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US / əˈraɪz /

UK / əˈraɪz /

A2
  • verb
  • To stand up
  • To result or happen due to a particular event

from

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US / frəm /

UK / frʌm, frɑm,frəm /

A1
  • preposition
  • Starting at a particular place, time or level

entirely

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US / ɪnˈtaɪəli /

UK / ɪnˈtaɪərli /

A2
  • adverb
  • Wholly; completely

out

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US / aʊt /

UK / aʊt /

A1
  • adverb
  • No longer stylish (e.g. fashion)
  • Away from home, business, or the usual place
  • In a direction/movement away from inside or center
  • noun
  • Act when a batter cannot continue playing
  • verb
  • To tell people a secret

share

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US / ʃeə(r) /

UK / ʃɛr /

A2
  • noun
  • Part-ownership in a property, business or company
  • Part of a company you own, shown by a certificate
  • verb
  • To divide something between two or more people
  • To allow others to use your things equally
  • To give information, etc. to someone

and

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US / ənd /

UK / ənd, ən,ænd /

A1
  • conjunction
  • Used to refer to two or more things
  • Plus; in addition; on top of that
  • Used to introduce an action that follows another

hope

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US / həʊp /

UK / hop /

A1
  • noun
  • When you wish something will happen; what you wish
  • verb
  • To expect and want something to happen

lot

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US / lɒt /

UK / lɑt /

A1
  • noun
  • What happens to a person in life from chance; fate
  • A group of people seen together
  • Item for sale at an auction
  • Small area of land used for a purpose e.g. parking

drink

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US / drɪŋk /

UK / drɪŋk /

A1
  • noun
  • A liquid that you put in your mouth
  • verb
  • To put water in your body through your mouth

diverse

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US / daɪˈvɜ:s /

UK / dɪˈvɚs, daɪ-, ˈdaɪˌvɚs /

B1
  • adjecitve
  • Being varied or different from each other
  • Very different from each other

early

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US / ˈɜ:li /

UK / ˈɜ:rli /

A1
  • adjecitve
  • Happening or appearing before
  • adverb
  • Coming/happening before others in a time sequence
  • Happening sooner than expected

large

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US / lɑ:dʒ /

UK / lɑ:rdʒ /

A1
  • adjecitve
  • Big; of great size; broad, tall, wide, or fat

most

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US / məʊst /

UK / most /

A1
  • adverb
  • Very; extremely
  • Greatest possible degree
  • pronoun
  • Nearly all of something

cancer

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US / 'kænsə(r) /

UK / ˈkænsɚ /

B1
  • noun
  • Any growth caused by abnormal cell division

completely

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US / kəmˈpli:tli /

UK / kəmˈpliːtli /

A1
  • adverb
  • In every way or as much as possible

milk

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US / mɪlk /

UK / mɪlk /

A1
  • noun
  • White liquid produced by females to feed babies
  • verb
  • To take white liquid from cows etc. to drink
  • To take as much from a person/situation as you can

only

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US / ˈəunli /

UK / ˈonli /

A1
  • adverb
  • Just one; just that amount or thing; not more than
  • Not very important or serious
  • Just that type of thing, person
  • Short time ago; not before a certain time
  • conjunction
  • Except; but

approve

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US / əˈpru:v /

UK / əˈpruv /

A2
  • verb
  • To formally accept something or grant permission
  • To have a positive opinion of someone or something

act

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US / ækt /

UK / ækt /

A1
  • noun
  • What someone did; action; behavior
  • A law or rule passed by a government we must obey
  • One of the parts that a stage play is divided into
  • verb
  • To behave in a certain way
  • To perform on a stage or in a movie

bit

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US / bɪt /

UK / bɪt /

A1
  • noun
  • Device put in a horse's mouth to control it
  • Small piece of something
  • verb
  • (E.g. of fish) to take bait and be caught

general

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US / 'dʒenrəl /

UK / ˈdʒɛnərəl /

A1
  • adjecitve
  • Widespread, normal or usual
  • noun
  • Top ranked officer in the army

human

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US / 'hju:mən /

UK / ˈhjumən /

A1
  • adjecitve
  • Concerning or characteristic of people
  • noun
  • A person; a man, woman or child

look

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US / lʊk /

UK / lʊk /

A1
  • noun
  • Person's beauty or physical attractiveness
  • Particular style of dress, clothes, or appearance
  • The way someone, something appears to be
  • Act of searching for or examining something
  • verb
  • To appear to be; seem

miss

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US / mɪs /

UK / mɪs /

A1
  • noun
  • Action of not hitting something or someone
  • Form of address to unmarried girl or woman
  • verb
  • To be absent
  • To fail to hit something e.g. a ball
  • To do without something
  • To fail to see or sense something
  • To fail to understand someone's message
  • To be too late to ride on something e.g. train
  • To feel you want to see someone who is not there

placebo

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US / plə'si:bəʊ /

UK / pləˈsibo /

B2
  • noun
  • Harmless pill for comparison in trial of new drug

possible

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US / ˈpɒsəbl /

UK / ˈpɑsəbəl /

A1
  • adjecitve
  • Being able or appropriate for a task or purpose
  • Having a chance of happening, or being true

all

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US / ɔ:l /

UK / ɔl /

A1
  • adverb
  • Completely; totally
  • determiner
  • Being every one of something
  • pronoun
  • 100% of something; the complete amount

everyone

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US / ˈevriwʌn /

UK / ˈɛvriˌwʌn /

A1
  • pronoun
  • Every person; everybody

journey

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US / 'dʒɜ:nɪ /

UK / ˈdʒɚni /

A2
  • noun
  • Act of traveling from one place to another; trip
  • verb
  • To travel through a place

produce

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US / prə'dju:s /

UK / prəˈdus, -ˈdjus, pro- /

A1
  • noun
  • Fresh foods such as fruits and vegetables
  • verb
  • To grow something naturally
  • To make something appear
  • To manufacture something using machines
  • To control the making a movie or television show

who

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US / hu: /

UK / hu /

A1
  • pronoun
  • Which person
  • Used to introduce information about people

work

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US / wɜ:k /

UK / wɚk /

A1
  • adjecitve
  • Activity completed in order to make money
  • noun
  • The product of some artistic or literary endeavor
  • Everything created by an author, artist, musician
  • Activity you do in order to make money
  • Place of employment
  • Final product or result of a some labor or effort
  • verb
  • To bring into a specific state of success
  • To be functioning properly, e.g. a car
  • To do your job in your company or workplace
  • To make an effort to do something
  • To operate a machine or device

billion

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US / ˈbɪljən /

UK / ˈbɪljən /

A2
  • noun
  • Number 1,000,000,000

between

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US / bɪˈtwi:n /

UK / bɪˈtwin /

A1
  • preposition
  • From one person, thing, or place, to another
  • In the space that separates two objects
  • Among two or more people who share something

device

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US / dɪˈvaɪs /

UK / dɪˈvaɪs /

A2
  • noun
  • Object, machine, or equipment for a specific use
  • Method of doing something; a way

risk

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US / rɪsk /

UK / rɪsk /

A1
  • noun
  • Actions that cause potential problems
  • verb
  • To do something potentially dangerous or foolish

they

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US / ðeɪ /

UK / ðe /

A1
  • pronoun
  • Two or more people, animals, or things

ago

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US / əˈgəʊ /

UK / əˈgoʊ /

A1
  • adverb
  • At a specified length of time in the past

move

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US / mu:v /

UK / muv /

A1
  • noun
  • Act of moving a playing piece in chess, etc.
  • An action; doing something
  • Step taken to achieve a goal
  • verb
  • To cause someone to have certain emotions
  • To cause something to change to a different place
  • To change where people live or a business operates
  • To take action to do or achieve something

reflect

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US / rɪ'flekt /

UK / rɪˈflɛkt /

A2
  • verb
  • To indicate or be a sign of something
  • To bounce back light, heat, sound from a surface
  • To show an image in glass, water, a mirror etc.
  • To think of something seriously and carefully

their

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US / ðɛː /

UK / ðer /

A1
  • determiner
  • Belonging to them

way

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US / weɪ /

UK / we /

A1
  • adverb
  • Used to emphasize the amount of something
  • noun
  • Particular aspect of something being thought about
  • One of various choices that could be made
  • Particular existing condition or state
  • (Often long) distance or length of time
  • How something is done
  • Route to go to a place
  • Small street
  • Usual behavior, emotions or habits of someone

breadth

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US / bredθ /

UK / brɛdθ /

B2
  • noun
  • Width; distance from one side to the another

change

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US / tʃeɪndʒ /

UK / tʃendʒ /

A1
  • noun
  • Exchange of one set of clothes for another
  • Money in the form of coins instead of paper
  • Money returned after giving too much
  • Act of making or becoming something else
  • verb
  • To exchange one set of clothes for another
  • To exchange one kind of money for another
  • To replace something with another thing
  • To make or become something else
  • To go from one train, bus, etc. and go to another

medicine

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US / ˈmedsn /

UK / ˈmɛdɪsɪn /

A2
  • noun
  • Something used in treating illness or pain
  • Science of preventing, treating, or curing disease

simple

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US / 'sɪmpl /

UK / ˈsɪmpəl /

A1
  • adjecitve
  • Not hard to understand or do; not complex
  • Having only a few parts; not complex
  • Being ordinary or normal
  • Being plain; without a lot added for style

theory

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US / ˈθiəri /

UK / ˈθiəri, ˈθɪri /

A2
  • noun
  • Ideas or principles that explain facts or events

compare

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US / kəm'peə(r) /

UK / kəmˈpɛr /

A1
  • verb
  • To consider how similar and different things are

involve

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US / ɪn'vɒlv /

UK / ɪnˈvɑlv /

A2
  • verb
  • To have or be included as a part of something

would

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US / wʊd /

UK / wʊd /

A1
  • other
  • Used to indicate something imagined
  • Used to ask or request something politely
  • Verb used to indicate possibility, request etc.
  • Used to indicate a preference
  • Used to indicate a reaction
  • Indicates something that occurred repeatedly
  • Used to indicate willingness or ability to do

book

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US / bʊk /

UK / bʊk /

A1
  • noun
  • Thing made of pages with writing on that you read
  • verb
  • (Police) to officially record someone's crimes
  • To reserve (hotel room, etc.) in advance
  • To produce a red or yellow card to a soccer player

currently

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US / ˈkʌrəntli /

UK / ˈkʌrənt(ə)li /

A2
  • adverb
  • Happening or being in the present time

expect

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US / ɪk'spekt /

UK / ɪkˈspɛkt /

A1
  • verb
  • To believe something is probably going to happen

safety

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US / ˈseɪfti /

UK / ˈsefti /

A1
  • noun
  • Device on a gun to prevent accidental shooting
  • State of being free from harm or danger

want

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US / wɔnt /

UK / wɑnt, wɔnt /

A1
  • noun
  • Something you desire or wish for
  • State or condition of poverty
  • verb
  • To desire or wish for something; hope for a thing

effect

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US / ɪ'fekt /

UK / ɪˈfɛkt /

A1
  • noun
  • An advantage, benefit
  • Change brought about by a cause; result

wide

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US / waɪd /

UK / waɪd /

A1
  • adjecitve
  • Having a great distance from one side to the other
  • adverb
  • Fully; completely

development

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US / dɪ'veləpmənt /

UK / dɪˈvɛləpmənt /

A2
  • noun
  • Act or process of growing bigger or more advanced
  • A new event related to a previous event

incredibly

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US / ɪnˈkredəbli /

UK / ɪnˈkrɛdəblɪ /

A2
  • adverb
  • To a great degree; very; amazingly

maybe

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US / ˈmeɪbi /

UK / ˈmebi /

A1
  • adverb
  • Possibly but not certainly; perhaps

our

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US / 'aʊə(r) /

UK / aʊr /

A1
  • determiner
  • Belonging to us

not

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US / nɒt /

UK / nɑt /

A1
  • adverb
  • Word indicating the negative
  • (Used to form the negative of verbs)

powerful

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US / ˈpauəful /

UK / ˈpaʊəfəl /

A2
  • adjecitve
  • Having control or influence over
  • Having a lot of physical force, energy, strength

quite

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US / kwaɪt /

UK / kwaɪt /

A1
  • adverb
  • Not very; fairly
  • Very; In a complete or total manner

yours

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US / jɔ:z /

UK / jʊrz, jɔrz, jorz /

A1
  • pronoun
  • Something the other person has

disease

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US / dɪˈzi:z /

UK / dɪˈziz /

A2
  • noun
  • Illness that affects a person, animal, or plant

prevent

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US / prɪ'vent /

UK / prɪˈvɛnt /

A2
  • verb
  • To stop something from happening or existing

same

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US / seɪm /

UK / sem /

A1
  • adjecitve
  • Being equal in quality and amount
  • Identical; not different
  • Not changing; constant

tiny

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US / 'taɪnɪ /

UK / ˈtaɪni /

A2
  • adjecitve
  • Very, very small

deal

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US / di:l /

UK / dil /

A1
  • verb
  • To cope with something - usually troubles
  • To give (something bad e.g. news) to
  • To buy and sell illegal drugs
  • To give out (cards, etc.) to; distribute
  • To do business with someone or to sell products

effectiveness

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US / ɪˌfek'tɪvnɪs /

UK / əˈfɛktɪvnɪs /

B2
  • noun
  • Degree of how well something works or is done

trial

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US / ˈtraɪəl /

UK / ˈtraɪəl, traɪl /

A2
  • adjecitve
  • Being made or done as a test or experiment
  • noun
  • Hearing and judgment of a case in court
  • Act or process of testing or experimenting
  • verb
  • To be made or done as a test or experiment

can

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US / kæn /

UK / kən,kæn /

A1
  • noun
  • A metal container for storing food
  • other
  • Able to; have the skill to; have the time to
  • verb
  • To have permission to
  • To be possible to do
  • To preserve food by sealing it in a metal container

record

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US / 'rekɔ:d /

UK / ˈrekərd /

A1
  • noun
  • Highest or most extreme level achieved
  • Round plastic disc on which music has been stored
  • History of a person's past actions or achievements
  • verb
  • To indicate a temperature, speed, etc.; register
  • To write down or say what happened
  • To put music, sounds onto a device to store it

but

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US / bət /

UK / bʌt,bət /

A1
  • conjunction
  • Used before you say something different, opposite

good

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US / ɡʊd /

UK / ɡʊd /

A1
  • adjecitve
  • Proper, appropriate or right
  • (Of an amount) enough; plenty
  • Excellent; high quality
  • Acting well or properly; of moral character
  • In a positive or happy emotional state
  • noun
  • Advantage or benefit

research

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US / rɪ'sɜ:tʃ /

UK / rɪˈsɚtʃ, ˈriˌsɚtʃ /

A2
  • noun
  • Study done to discover new ideas and facts
  • Work done to find or discover knowledge
  • verb
  • To study in order to discover new ideas and facts

blood

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US / blʌd /

UK / blʌd /

A2
  • adjecitve
  • Related by birth; family
  • noun
  • Red liquid in the bodies of people and animals
  • verb
  • To be initiated into something, e.g. a secret club

group

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US / ɡru:p /

UK / ɡrup /

A1
  • noun
  • Two or more musicians who play music together
  • Number of people or things gathered together
  • verb
  • To combine or collect objects or people together

hundred

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US / 'hʌndrəd /

UK / ˈhʌndrɪd /

A1
  • number
  • 100

accord

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US / ə'kɔ:d /

UK / əˈkɔ:rd /

B1
  • noun
  • Agreement or harmony
  • An agreement or treaty between countries
  • verb
  • To be in harmony or agreement; consent
  • To give (someone) the respect due to them

low

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US / ləʊ /

UK / lo /

A1
  • adjecitve
  • Having a small quantity, supply, or amount
  • Being unhappy or unpleasant in attitude
  • Not high; being near the ground, or bottom
  • (Of a voice, sound) being soft; quiet
  • noun
  • Situation of not having a lot of something

see

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US / si: /

UK / si /

A1
  • verb
  • To go on a date with someone
  • To predict whether something is, or will be true
  • To understand what someone says
  • To use your eyes to look at something
  • To visit a place often for sightseeing or pleasure
  • To visit or meet with someone
  • To find out by waiting or looking
  • To watch (a game, movie or TV show)

history

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US / 'hɪstrɪ /

UK / ˈhɪstəri /

A2
  • noun
  • Established pattern or record
  • Study of past events as an academic subject

overlook

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US / ˌəʊvəˈlʊk /

UK / ˌoʊvərˈlʊk /

B1
  • verb
  • To look down on; be able to see from
  • To miss noticing a mistake or problem

have

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US / həv /

UK / hæv /

A1
  • verb
  • To drink, smoke, eat or use something
  • To experience the effects of something
  • To organize an event, or join in an activity
  • To own, possess, or hold something
  • To cause to happen or produce a particular effect

information

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US / ˌɪnfəˈmeɪʃn /

UK / ˌɪnfɚˈmeʃən /

A1
  • noun
  • Collection of facts and details about something

clear

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US / klɪə(r) /

UK / klɪr /

A1
  • adjecitve
  • Empty; without anything in it or on it
  • Being certain and without doubt
  • Being without any streaks, spots, or cracks
  • Easy to understand; well-explained; obvious
  • adverb
  • Completely; entirely; through the whole of
  • Away from; free from
  • verb
  • To recover from or remove a problem
  • To get rid of the entire contents of
  • To give permission for something to happen
  • To make a place or surface empty by removing
  • To prove that someone is not guilty or to blame

next

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US / nekst /

UK / nɛkst /

A1
  • adverb
  • The one that follows another in time or order
  • At a time or place directly after the present one
  • noun
  • The one that follows after
  • adjecitve
  • Immediately after the previous one
  • First occurrence after the present one

raise

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US / reɪz /

UK / rez /

A1
  • noun
  • Increase in a bet above another when playing cards
  • Pay increase
  • verb
  • To increase a bet above another when playing cards
  • To gather donations for a cause or charity
  • To bring up and educate a child to maturity
  • To bring a dead person to life
  • To increase a quantity, size, intensity or price
  • To lift (e.g. your hand) to a higher position
  • To mention a topic /issue for discussion; bring up
  • To increase (salary, etc.)
  • To grow or care for plants or animals

problem

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US / ˈprɒbləm /

UK / ˈprɑbləm /

A1
  • adjecitve
  • Causing trouble
  • noun
  • Something difficult to deal with or causes trouble
  • Question to show understanding of a math concept

scientist

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US / ˈsaɪəntɪst /

UK / ˈsaɪəntɪst /

A2
  • noun
  • Person who is trained in a science

review

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US / rɪˈvju: /

UK / rɪˈvju /

A2
  • noun
  • Examination of soldiers and supplies
  • Opinion, as in a paper, about movie, book, or play
  • Studying again to remind yourself about something
  • verb
  • To carefully look at the quality of something
  • To formally examine something in the military
  • To write an opinion about movie, book, or play
  • To study again to remind yourself about something

worldwide

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US / ˈwɜ:ldwaɪd /

UK / ˈwɚldˈwaɪd /

B1
  • adjecitve
  • Spanning or extending throughout the entire world
  • adverb

recently

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US / ˈri:sntli /

UK / 'risṇtlɪ /

A1
  • adverb
  • Just a while ago; not long ago

spelt

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US / spelt /

UK / spɛlt /

A2
  • verb
  • To be able to write (or say) the letters of a word

with

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US / wɪð /

UK / wɪð, wɪθ /

A1
  • preposition
  • As an employee of a certain company
  • Against something or someone
  • By using something as a means
  • Due to; because of
  • Including
  • Possessing as a feature
  • Related to
  • (Of the manner/attitude by which you do something)
  • Used to express that people or things are together

could

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US / kəd /

UK / kʊd /

A1
  • other
  • Past form of 'can' to mean have ability
  • Used to ask for something politely, or to offer

often

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US / ˈɔfən /

UK / ˈɔfən,ˈɑfən,ˈɔftən,ˈɑf- /

A1
  • adverb
  • Many times; frequently; on many occasions

precise

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US / prɪ'saɪs /

UK / prɪˈsaɪs /

A2
  • adjecitve
  • (Of language details etc.) Very accurate and exact
  • (Of a time, place, quality) exact
  • Being very careful about how you do things

end

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US / end /

UK / ɛnd /

A1
  • noun
  • The point where a process or activity stops
  • A point that marks the limit of something; finish
  • Goal or desired result
  • The tip, edge or limit of something
  • verb
  • To be the last part of something

sample

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US / ˈsɑ:mpl /

UK / ˈsæmpl /

A2
  • noun
  • A small quantity of something used as a taster
  • verb
  • To try (e.g. food, drink), to see if you like it

uncover

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US / ʌn'kʌvə(r) /

UK / ʌnˈkʌvɚ /

B1
  • verb
  • To remove what is on top to show something
  • (Journalist) to discover some news to be reported

actually

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US / ˈæktʃuəli /

UK / ˈæktʃuəli /

A1
  • adverb
  • Used to add new (often different) information

ensure

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US / ɪn'ʃʊə(r) /

UK / ɛnˈʃʊr /

A2
  • verb
  • To make something sure, certain, or safe

speak

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US / spi:k /

UK / spik /

A1
  • verb
  • To be able to use a certain language
  • To use words to tell information, express thoughts

use

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US / ju:s /

UK / ju:s /

A1
  • noun
  • Ability to employ something
  • Need to enable it to work
  • Permission to do something with something
  • Act of spending money
  • Operation of a machine for its function
  • verb
  • To have; to eat, drink, consume etc.
  • To need to operate or work
  • To operate a machine, e.g. a computer
  • To treat a person badly
  • To do something with, for a task or purpose

after

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US / 'ɑ:ftə(r) /

UK / ˈæftɚ /

A1
  • adverb
  • Later than another time, or behind something
  • conjunction
  • Following something before
  • preposition
  • When an event happened or time has passed

appear

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US / ə'pɪə(r) /

UK / əˈpɪr /

A1
  • verb
  • To be seen, become visible; come into sight
  • To seem to be
  • To act in a play, movie, or be mentioned in media

drug

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US / drʌɡ /

UK / drʌɡ /

A2
  • noun
  • Illegal substance taken for effect on the mind
  • Chemical used as a medicine
  • verb
  • To give drugs to someone to make them sleep

many

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US / 'menɪ /

UK / ˈmɛni /

A1
  • determiner
  • Used to refer a large number of things

thousand

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US / ˈθaʊznd /

UK / ˈθaʊzənd /

A1
  • number
  • Number 1,000

will

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US / wɪl /

UK / wɪl /

A1
  • noun
  • Desire or choice of someone
  • Document saying who gets your money when you die
  • Strong desire to do something; determination
  • Desire to do something; strong wish to do
  • other
  • Used with verbs to express the future
  • verb
  • To leave property to someone after your death
  • To use mental effort to make something happen
  • Am (is, are) likely to do
  • To influence someone to do something
  • To make something happen by strongly wanting it

side

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US / saɪd /

UK / saɪd /

A1
  • adjecitve
  • In addition to the central or most important thing
  • Next to, or very close to, the right or left of
  • noun
  • Position or opinion that is opposite to another
  • Right or left part of a person's body
  • Feature of someone's personality
  • Straight edge of an object
  • One of two or more groups fighting each other
  • verb
  • To decide to agree with one point, not the other

here

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US / hɪə(r) /

UK / hɪr /

A1
  • adverb
  • In this place; at this location, position or time

new

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US / nju: /

UK / nu, nju /

A1
  • adjecitve
  • Not old, recently born, built or made
  • Being or doing something for the first time
  • Not felt, seen or known previously
  • Having been recently bought or obtained

small

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US / smɔ:l /

UK / smɔl /

A1
  • adjecitve
  • Little in size; not big
  • (Of letters) not written in capital letters
  • Being insignificant or minor
  • (Of a business) with few people or things; local
  • (Of voice) being soft and quiet
  • (Of a child) being young

try

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US / traɪ /

UK / traɪ /

A1
  • noun
  • Act of putting the ball over the rugby goal line
  • verb
  • To make an effort, to attempt to do something
  • To examine someone or something in a court of law
  • To test to see if it is good or you like it
  • To make a person go through hardship; test
  • To examine something to see if it works

medical

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US / ˈmedɪkl /

UK / ˈmɛdɪkəl /

A2
  • adjecitve
  • Of or relating to physical health or medicine
  • noun
  • A health check or test

science

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US / 'saɪəns /

UK / ˈsaɪəns /

A2
  • noun
  • Study of the physical world, based on facts

sort

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US / sɔ:t /

UK / sɔrt /

A1
  • noun
  • Group or class of similar things or people
  • verb
  • To organize things by putting them into groups
  • To deal with things in an organized way

develop

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US / dɪ'veləp /

UK / dɪˈvɛləp /

A1
  • verb
  • To explain something in steps and in detail
  • To create or think of something
  • To grow bigger, more complex, or more advanced
  • To make a photograph from film

heavily

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US / ˈhevɪli /

UK / hɛvəli /

A2
  • adverb
  • In a slow, loud manner
  • A lot or to a great degree
  • With great effort or force

explain

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US / ɪk'spleɪn /

UK / ɪkˈsplen /

A1
  • verb
  • To make clear or easy to understand by describing

marker

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US / ˈmɑ:kə(r) /

UK / ˈmɑ:rkə(r) /

B1
  • noun
  • Something that is easy to recognize or identify
  • Thick pen used for writing, e.g. on boards

sure

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US / ʃʊə(r) /

UK / ʃʊr /

A1
  • adjecitve
  • Having no doubts about something
  • Have confidence in your own words or actions
  • Firmly established or held; being firm or stable
  • Being correct or true
  • adverb
  • What you say to agree willingly

population

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US / ˌpɒpjuˈleɪʃn /

UK / ˌpɑpjəˈleʃən /

A2
  • noun
  • Number of people who live in a country, area etc.

someone

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US / ˈsʌmwʌn /

UK / ˈsʌmˌwʌn, -wən /

A1
  • pronoun
  • Person who is not known or named

story

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US / 'stɔ:rɪ /

UK / ˈstɔri, ˈstori /

A1
  • noun
  • One of many floors or levels in a building
  • Account or description of how something happened
  • Introduction to Video Content
  • What's missing in medical research? Medical science has a problem—it’s missing something. Something that means that not only is it harder to find the causes of some diseases—and effective ways to treat them—some diseases are getting overlooked entirely. It turns out what it’s missing could be you—but I’ll get to that in a bit.Because first, a story. Or 8 billion stories, to be precise. See, our DNA is our body's instruction manual, sure. But it’s also a history book that records our own, unique genetic story.All our stories begin around 300,000 years ago when humans arose in Africa. Some genetic stories tell of leaving a couple of hundred thousand years later, journeying into Europe, East Asia, or the Americas. Some genetic stories speak of expanding empires. Others the diseases we evolved to ward off, and some the simple act of settling down, raising cattle, and drinking their milk.Each of our genetic stories are different, but maybe not as different as you might expect. We share 99.9% of our DNA with each other. Our stories are 99.9% identical, but that 0.1% difference is incredibly powerful. In that tiny difference between our genetic stories is where we have the potential to develop better treatments for diseases—treatments that work for everyone.But medical science isn’t currently reading all those stories. To explain, let me tell you how researchers work out the causes of diseases, and develop and test the effectiveness and safety of new treatments.To find out the causes of a particular disease, researchers find lots of people who have that condition and comb through their genetic stories. They look for little variations they share—little bits of their DNA stories that are spelt differently. If they find some, they try all sorts of different ways of dealing with the effect of them.The problem is that most medical research relies on data from a small, homogenous group of people. For a long time, medical research has used a mostly white, male sample size. This means that diseases that predominantly affect other races or genders may not get the attention they deserve. And that 0.1% difference in our DNA? It can be significant when it comes to developing effective treatments. By expanding the diversity of the samples used in medical research, we have a better chance of finding those genetic variations that contribute to diseases and developing treatments that work for everyone. This means not only considering different racial and ethnic backgrounds but also gender and other factors.The good news is that efforts are being made to increase diversity in medical research. The All of Us Research Program, for example, aims to gather data from at least one million people to improve health outcomes for all. By including a wide range of individuals, the program hopes to discover new insights into diseases, develop personalized treatments, and ultimately revolutionize medical research.So, what's missing in medical research? You. Your unique genetic story could hold the key to finding better treatments for diseases. By including diverse populations in medical research, we can ensure that no disease or individual is overlooked. It's time to bridge the gap and harness the power of our genetic diversity for the benefit of all.
  • Subtitles section
  • Medical science has a problem— it's missing something.
  • Something that means that not only is it harder to find the causes of some diseases— and effective ways to treat them— some diseases are getting overlooked entirely.
  • It turns out what it's missing could be you— but I'll get to that in a bit.
  • Because first, a story.
  • Or 8 billion stories, to be precise.
  • See, our DNA is our body's instruction manual, sure.
  • But it's also a history book that records our own, unique genetic story.
  • All our stories begin around 300,000 years ago when humans arose in Africa.
  • Some genetic stories tell of leaving a couple of hundred thousand years later, journeying into Europe, East Asia, or the Americas.
  • Some genetic stories speak of expanding empires.
  • Others the diseases we evolved to ward off, and some the simple act of settling down, raising cattle, and drinking their milk.
  • Each of our genetic stories are different, but maybe not as different as you might expect.
  • We share 99.9% of our DNA with each other.
  • Our stories are 99.9% identical, but that 0.1% difference is incredibly powerful.
  • In that tiny difference between our genetic stories is where we have the potential to develop better treatments for diseases— treatments that work for everyone.
  • But medical science isn't currently reading all those stories.
  • To explain let me tell you how researchers work out the causes of diseases, and develop and test the effectiveness and safety of new treatments.
  • To find out the causes of a particular disease, researchers find lots of people who have that condition and comb through their genetic stories.
  • They look for little variations they share— little bits of their DNA stories that are spelt differently.
  • If they find some, then they try all sorts of different ways of dealing with the effect of them.
  • And if that uncovers something that looks promising, they then run a clinical trial to see if it actually is.
  • In phase one, a small group of volunteers try the treatment.
  • Well, often only half of them do, with the other half getting a placebo that does absolutely nothing.
  • If there aren't any notable side effects at the target dose, the treatment is cleared to move on to the next stage of the clinical trial.
  • Phase two, this time with a bigger group of participants who all have the condition the researchers hope the drug will treat.
  • If the drug appears effective, it moves on to phase three, with more participants trying it for even longer.
  • Only after all this is the new treatment then reviewed and— hopefully— approved for use by us, the general population.
  • But there's a problem with it.
  • Here is the ethnicity of lots and lots of people used to recently find the causes of various diseases.
  • And here is how that compares to the ethnic diversity of the world's population.
  • Spot the difference?
  • The genetic stories that researchers are combing through are heavily biased to those of people from European descent.
  • Which means that if you're searching for those disease-causing bits of DNA to target new drugs against, and you're mainly reading the stories of people of European descent, you might completely overlook key bits in the stories of other diverse groups that tell of, say,
  • a changed risk of disease or even shed light on how a disease occurs— for example, scientists may not have found the mutation that causes sickle cell disorder if we'd only looked in the stories of people of European descent.
  • And the thing is, what medical science is missing doesn't end there.
  • When new treatments or medical devices are being tested, they need to be tested on everyone that may use them.
  • If the genetic stories involved don't reflect the breadth of stories in our worldwide library then, again, something might be missed.
  • Take, for example, the medicine Warfarin; used to prevent blood clots.
  • Researchers have found that, to produce the same effect, most people of East Asian descent need a lower dose than some people of European descent, and most people of African ethnicity need a larger dose.
  • Which means the dose that works best for someone may vary according to their ethnicity.
  • It's this kind of important information that can be missed if clinical trials don't include people from across a range of ethnicities.
  • So what's the solution?
  • Well, it's quite simple... in theory.
  • In order to develop treatments that work better for everyone, we need to involve everyone's stories in medical research— in the early stage research, in the drug development process, and right through the clinical trial.
  • The good news is that more and more people are thinking about this.
  • For example, cancer researchers at University College London researching genetic markers for cancer want to analyze tissue samples from a wide range of ethnicities so that the biomarkers of cancer they identify will be relevant for people from as many ethnicities as possible.
  • Bottom line: medical science needs to ensure it's got the best library it can have— the one with the widest collection of genetic stories possible, so that everyone's story can be considered— including yours.
  • That is the only way to ensure everyone, everywhere can get the best medical treatment they possibly can.